Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Malgorzata Kubicka-Muranyi"'
Publikováno v:
Archives of Toxicology. 69:450-459
The oxidizing capacity of phagocytic cells is suspected to play a major role in the generation of immunogenic drug metabolites, in particular those that cause extrahepatic immunopathological lesions. In the case of the antirheumatic drug gold(I) diso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43a54341356513d1c070013632f97b19
https://doi.org/10.1007/s002040050198
https://doi.org/10.1007/s002040050198
Autor:
Peter Griem, Malgorzata Kubicka-Muranyi, Reinhard Lührmann, Birgit Lübben, Norbert Rottmann, Ernst Gleichmann
Publikováno v:
International Archives of Allergy and Immunology. 108:1-10
HgCl2 treatment of B10.S mice induces IgG autoantibodies to fibrillarin, a component of small nuclear ribonucleoprotein particles, and histone. Here, we demonstrate the activation by HgCl2 of autoreactive T cells specific for these nuclear proteins.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11d0830e258f9d2a3255ecfc6e1dfb53
https://doi.org/10.1159/000237110
https://doi.org/10.1159/000237110
Autor:
Joachim Bister, Olaf Behmer, Ernst Gleichmann, Malgorzata Kubicka-Muranyi, Hanne Klonowski, Markus Uhrberg
Publikováno v:
International Journal of Immunopharmacology. 15:151-161
The adoptive transfer popliteal lymph node assay (PLNA) was used to demonstrate Hg-specific T-cell responses of mice that were continuosly treated with HgCl2 by a regimen known to induce a systemic autoimmune disease in H-2s (rmmurine histocompatabil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d0bcae1812e440713f56ebe1ac3fd15
https://doi.org/10.1016/0192-0561(93)90091-c
https://doi.org/10.1016/0192-0561(93)90091-c
Autor:
Malgorzata Kubicka-Muranyi, Joachim Kremer, Ruud Albers, Reinhard Lührmann, Nanne Bloksma, Norbert Rottmann, Birgit Lübben, Ernst Gleichmann
Publikováno v:
International archives of allergy and immunology. 109(1)
HgCl2 induces a CD4+ T-cell-dependent systemic autoimmune disease in susceptible strains of rats and mice. In rats, autoreactive T cells were shown to be involved, whereas in mice, attention has focussed on the demonstration of 'Hg-specific' T cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::612c792b7c2c7fdf7078d8ea7f18c308
https://pubmed.ncbi.nlm.nih.gov/8527945
https://pubmed.ncbi.nlm.nih.gov/8527945
Autor:
Helga Gleichmann, Nanne Bloksma, Hans-Christian Schuppe, Ernst Gleichmann, Malgorzata Kubicka-Muranyi
Publikováno v:
Critical reviews in toxicology. 25(5)
This article reviews results obtained with popliteal lymph node assays (PLNAs) in rodents and discusses their ability to detect and analyze immunotoxic effects of drugs and other low molecular weight (LMW) chemicals. In its basic form, the PLNA measu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4313f3d188aa278e2196d3edc6c2b031
https://pubmed.ncbi.nlm.nih.gov/8845063
https://pubmed.ncbi.nlm.nih.gov/8845063
Autor:
Reinhard Lührmann, Malgorzata Kubicka-Muranyi, Birgit Lübben, Norbert Rottmann, Ernst Gleichmann
Publikováno v:
Molecular biology reports. 20(2)
Autoantibodies against nucleolar components are a common serological feature of patients suffering from scleroderma, a collagen vascular autoimmune disease. An important target of these autoantibodies is a protein with an apparent molecular weight of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e68547cee35a982463eefebdb6a965b0
https://pubmed.ncbi.nlm.nih.gov/7536297
https://pubmed.ncbi.nlm.nih.gov/7536297
Publikováno v:
Symposium in Immunology I and II ISBN: 9783540564782
Adverse immune reactions to drugs, sometimes termed drug hypersensitivity reactions, account for a considerable proportion of all adverse drug reactions [32]. These reactions pose a difficult problem for the development of new drugs because they are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b37b0cda113dfc665ab44aabef94e03
https://doi.org/10.1007/978-3-642-78087-5_17
https://doi.org/10.1007/978-3-642-78087-5_17
Publikováno v:
Archives of toxicology. 65(8)
We used a modified version of the popliteal lymph node assay in rats to investigate the immunosuppressive potential of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). In 10 months we conducted 3 experimental series. Animals were treated with single s.c.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4df91ae79e53e03174f4a53224c2468
https://pubmed.ncbi.nlm.nih.gov/1747065
https://pubmed.ncbi.nlm.nih.gov/1747065
Publikováno v:
Toxicology Letters. 74:29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::061ae28bf8bd1d4273531f1ef0f24101
https://doi.org/10.1016/0378-4274(94)90281-x
https://doi.org/10.1016/0378-4274(94)90281-x