Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Malgorzata E. Smas"'
Autor:
Daniel A. Haber, Shyamala Maheswaran, Mehmet Toner, Sridhar Ramaswamy, Matthew R. Smith, Lecia V. Sequist, Chin-Lee Wu, Neil H. Bander, Julie Trautwein, Brian W. Brannigan, Jenna B. Lord, Malgorzata E. Smas, Matthew Ulman, Ben S. Wittner, David T. Ting, Shannon L. Stott, Richard J. Lee, David T. Miyamoto
PDF file - 110K, Supplemental Tables. (S1) Clinical characteristics and CTC data for metastatic prostate cancer patients treated with hormonal therapy. (S2) Time course data for metastatic prostate cancer patients treated with hormonal therapy and an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::898c2949d0aa4baefe653c182ec7a79a
https://doi.org/10.1158/2159-8290.22529109.v1
https://doi.org/10.1158/2159-8290.22529109.v1
Autor:
Daniel A. Haber, Shyamala Maheswaran, Mehmet Toner, Sridhar Ramaswamy, Matthew R. Smith, Lecia V. Sequist, Chin-Lee Wu, Neil H. Bander, Julie Trautwein, Brian W. Brannigan, Jenna B. Lord, Malgorzata E. Smas, Matthew Ulman, Ben S. Wittner, David T. Ting, Shannon L. Stott, Richard J. Lee, David T. Miyamoto
PDF file - 49K, Supplemental Methods for (a) single molecule sequencing and AR transcriptional signature, (b) HB CTC-chip fabrication, (c) HB CTC-chip blood processing, and (d) automated fluorescence microscopy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c334280fe9bed23d02edc461b999acf
https://doi.org/10.1158/2159-8290.22529112
https://doi.org/10.1158/2159-8290.22529112
Autor:
David T. Miyamoto, Shyamala Maheswaran, Jonathan G. Goldin, Richard T. Lee, Philip J. Saylor, Daniel A. Haber, Carol Gurski, Wanling Xie, M. Dror Michaelson, S. Michael Rothenberg, Malgorzata E. Smas, Matthew R. Smith
Publikováno v:
Clinical Cancer Research. 19:3088-3094
Background: Cabozantinib is an oral MET/VEGFR2 inhibitor. A recent phase II study of cabozantinib (100 mg daily) showed improved bone scans in subjects with metastatic castration-resistant prostate cancer (mCRPC), but adverse events (AE) caused frequ
Autor:
Shannon L. Stott, Mehmet Toner, Jenna B. Lord, Matthew R. Smith, Shyamala Maheswaran, Neil H. Bander, Sridhar Ramaswamy, David T. Ting, Julie Trautwein, Richard T. Lee, Daniel A. Haber, Brian W. Brannigan, David T. Miyamoto, Lecia V. Sequist, Matthew J. Ulman, Ben S. Wittner, Malgorzata E. Smas, Chin-Lee Wu
Publikováno v:
Cancer Discovery. 2:995-1003
Androgen deprivation therapy (ADT) is initially effective in treating metastatic prostate cancer, and secondary hormonal therapies are being tested to suppress androgen receptor (AR) reactivation in castration-resistant prostate cancer (CRPC). Despit
Autor:
Brinda Alagesan, Daniel A. Haber, Malgorzata E. Smas, David P. Ryan, Suchismita Paul, Gianmarco Contino, Nabeel Bardeesy, Min Yu, Brian W. Brannigan, Sridhar Ramaswamy, Fatih Ozsolak, Patrice M. Milos, Ben S. Wittner, Jordan C. Ciciliano, Mehmet Toner, David T. Ting, Daniel Winokur, Kristina Xega, Matthew J. Ulman, Anna J. Gilman, Lecia V. Sequist, Shannon L. Stott, Shyamala Maheswaran
Publikováno v:
Nature
Circulating tumour cells (CTCs) shed into blood from primary cancers include putative precursors that initiate distal metastases. Although these cells are extraordinarily rare, they may identify cellular pathways contributing to the blood-borne disse
Autor:
Shannon L. Stott, David T. Miyamoto, Daniel Irimia, Min Yu, Sunitha Nagrath, Dina Tsukrov, Mehmet Toner, Daniel Winokur, Richard T. Lee, Chia-Hsien Hsu, Kurt J. Isselbacher, S. Michael Rothenberg, Malgorzata E. Smas, Simeon Springer, Lecia V. Sequist, Jenna B. Lord, George K. Korir, Daniel A. Haber, Ajay Shah, Shyamala Maheswaran, Belinda A. Waltman, Frederick P. Floyd, Anna J. Gilman
Publikováno v:
Proceedings of the National Academy of Sciences. 107:18392-18397
Rare circulating tumor cells (CTCs) present in the bloodstream of patients with cancer provide a potentially accessible source for detection, characterization, and monitoring of nonhematological cancers. We previously demonstrated the effectiveness o
Autor:
Daniel A. Haber, Aditya Bardia, Maria C. Donaldson, José Baselga, Ben S. Wittner, Jordan C. Ciciliano, Elena F. Brachtel, David T. Ting, Kyle Concannon, Min Yu, Dennis C. Sgroi, Shannon L. Stott, Sridhar Ramaswamy, Lecia V. Sequist, Mehmet Toner, Malgorzata E. Smas, Marissa N. Wells, Ajay Shah, Steven J. Isakoff, Shyamala Maheswaran
Publikováno v:
Science (New York, N.Y.). 339(6119)
Cells in Transit(ion) Epithelial-mesenchymal transition (EMT) is a developmental program that converts adherent epithelial cells to a migratory mesenchymal state. This cell-fate change has been linked to tumor metastasis in preclinical models. To inv
Autor:
Lecia V. Sequist, Shannon L. Stott, Ajay Shah, David T. Ting, José Baselga, Kyle Concannon, Aditya Bardia, Daniel A. Haber, Dennis C. Sgroi, Min Yu, Elena F. Brachtel, Malgorzata E. Smas, Ben S. Wittner, Jordan C. Ciciliano, Mehmet Toner, Sridhar Ramaswamy, Shyamala Maheswaran, Marissa N. Wells, Steven J. Isakoff, Maria C. Donaldson
Publikováno v:
Cancer Research. 73:A75-A75
Epithelial mesenchymal transition (EMT) has been postulated to contribute to the dissemination of cancer cells, but supporting histopathological evidence is limited. We used a microfluidic device to isolate circulating tumor cells (CTCs), combined wi
Autor:
Ajay Shah, Aditya Bardia, Sridhar Ramaswamy, Kyle Concannon, Malgorzata E. Smas, Daniel A. Haber, Ben S. Wittner, Jordan C. Ciciliano, Marissa N. Wells, Min Yu, L.V. Sequist, José Baselga, Shyamala Maheswaran, Mehmet Toner, David T. Ting, Elena F. Brachtel, Dennis C. Sgroi, SJ Isakoff, Shannon L. Stott
Publikováno v:
Cancer Research. 72:P2-01
Epithelial to mesenchymal transition (EMT) has been postulated to contribute to the migration and dissemination of cancer cells, but supporting histopathological evidence is limited. We used a microfluidic device to isolate circulating tumor cells (C
Autor:
Matthew J. Ulman, Brinda Alagesan, Suchismita Paul, Ben S. Wittner, Jordan C. Ciciliano, Malgorzata E. Smas, Shyamala Maheswaran, Sridhar Ramaswamy, Daniel A. Haber, Min Yu, Kristina Xega, Mehmet Toner, Daniel Winokur, David T. Ting, David P. Ryan, Brian W. Brannigan, Gianmarco Contino, Fatih Ozsolak, Nabeel Bardeesy, Shannon L. Stott, Patrice M. Milos, Lecia V. Sequist, Anna J. Gilman
Publikováno v:
Nature. 490:570-570
Corrigendum: RNA sequencing of pancreatic circulating tumour cells implicates WNT signalling in metastasis