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of 9
pro vyhledávání: '"Malgorzata E. Quinn"'
Autor:
Malgorzata E. Quinn, Qingnian Goh, Mitsutoshi Kurosaka, Dilani G. Gamage, Michael J. Petrany, Vikram Prasad, Douglas P. Millay
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Cellular fusion is fundamental for skeletal muscle development. Here the authors show that myomerger is expressed in myoblasts, is essential for myoblast fusion in mice, and in co-operation with myomaker confers fusogenic ability to non-fusogenic cel
Externí odkaz:
https://doaj.org/article/f9517f4aa0cf41ccb0945886204443b1
Autor:
Leonid V. Chernomordik, Eugenia Leikina, Anthony Ratinov, Douglas P. Millay, Malgorzata E. Quinn, Dilani G. Gamage
Publikováno v:
Journal of Biological Chemistry. 292:17272-17289
Multinucleated skeletal muscle fibers form through the fusion of myoblasts during development and regeneration. Previous studies identified myomaker (Tmem8c) as a muscle-specific membrane protein essential for fusion. However, the specific function o
Autor:
Yasuyuki Mitani, Yi Li Min, Douglas P. Millay, Malgorzata E. Quinn, Dilani G. Gamage, Rhonda Bassel-Duby, Eric N. Olson
Publikováno v:
Proceedings of the National Academy of Sciences. 113:2116-2121
During skeletal muscle development, myoblasts fuse to form multinucleated myofibers. Myomaker [Transmembrane protein 8c (TMEM8c)] is a muscle-specific protein that is essential for myoblast fusion and sufficient to promote fusion of fibroblasts with
Autor:
Douglas P. Millay, Malgorzata E. Quinn, Dilani G. Gamage, Mitsutoshi Kurosaka, Vikram Prasad, Qingnian Goh, Michael J. Petrany
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Despite the importance of cell fusion for mammalian development and physiology, the factors critical for this process remain to be fully defined, which has severely limited our ability to reconstitute cell fusion. Myomaker (Tmem8c) is a muscle-specif
Autor:
Douglas P. Millay, Malgorzata E. Quinn, Qingnian Goh, Vikram Prasad, Michael J. Petrany, Dilani G. Gamage, Mitsutoshi Kurosaka
Despite the importance of cell fusion for mammalian development and physiology, the factors critical for this process remain to be fully defined1. This lack of knowledge has severely limited our ability to reconstitute cell fusion, which is necessary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12a14c15da955c905707ae330de15f2d
Publikováno v:
Pediatric research
Mutations in Zinc Finger Protein of the Cerebellum 3 (ZIC3) cause X-linked heterotaxy and isolated cardiovascular malformations. Recent data suggest a potential cell-autonomous role for Zic3 in myocardium via regulation of Nppa and Tbx5. We sought to
Publikováno v:
Human Molecular Genetics. 21:1888-1896
Limb anomalies are important birth defects that are incompletely understood genetically and mechanistically. GLI3, a mediator of hedgehog signaling, is a genetic cause of limb malformations including pre- and postaxial polydactyly, Pallister–Hall s
In humans, loss-of-function mutations in ZIC3 cause isolated cardiovascular malformations and X-linked heterotaxy, a disorder with abnormal left-right asymmetry of organs. Zic3 null mice recapitulate the human heterotaxy phenotype but also have early
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc122e7243b11ea55724efc17dd076bf
https://europepmc.org/articles/PMC3633368/
https://europepmc.org/articles/PMC3633368/
Autor:
Thomas M Glaser, Malgorzata E. Quinn, Nadean L. Brown, Amy N. Riesenberg, Joseph A. Brzezinski, Robert B. Hufnagel
Publikováno v:
Molecular and cellular neurosciences. 54
Retinal neurons and glia arise from a common progenitor pool in a temporal order, with retinal ganglion cells (RGCs) appearing first, and Müller glia last. The transcription factors Atoh7/Math5 and Ascl1/Mash1 represent divergent bHLH clades, and ex