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pro vyhledávání: '"Malgorzata Drewniak-Deyrup"'
Autor:
Scott W. Smith, Malgorzata Drewniak-Deyrup, Pascal Druzgala, Nicholas Bodor, James J. Kaminski, David Winwood
Publikováno v:
Pharmaceutical Research. :372-377
The synthesis of an homologous series of new water-soluble derivatives of pilocarpine is described. The new compounds, referred to as soft quaternary salts, are water soluble by virtue of a cationic ammonium head and their lipophilicity can be modula
Publikováno v:
Journal of Heterocyclic Chemistry. 26:829-836
Indole, carbazole, pyrrole, imidazole, benzimidazole, 2-methyl- and 2-phenylbenzimidazole, and 1, 2, 4-triazole have each been converted into their N-(benzotriazol-1-ylmethyl) derivatives. The pyrrole, indole, and carbazole adducts undergo smooth lit