Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Malgorzata Bielinska"'
Autor:
Rebecca Cochran, Helka Parviainen, Ann-Kathrin Löbs, Antti Kyrönlahti, Marjut Pihlajoki, David B. Wilson, Anja Schrade, Markku Heikinheimo, Melanie Vetter, Malgorzata Bielinska, Patrick Y. Jay, Justyna Krachulec
Publikováno v:
Endocrinology. 153:2599-2611
In response to gonadectomy certain inbred mouse strains develop sex steroidogenic adrenocortical neoplasms. One of the hallmarks of neoplastic transformation is expression of GATA4, a transcription factor normally present in gonadal but not adrenal s
Publikováno v:
Veterinary Pathology. 46:194-210
Neoplastic adrenocortical lesions are common in humans and several species of domestic animals. Although there are unanswered questions about the origin and evolution of adrenocortical neoplasms, analysis of human tumor specimens and animal models in
Autor:
Markku Heikinheimo, William T. Pu, Jonathan M. Erlich, Susanna Mannisto, David B. Wilson, Patrick Y. Jay, Malgorzata Bielinska
Publikováno v:
Developmental Biology. 301:602-614
Congenital diaphragmatic hernia (CDH) is an often fatal birth defect that is commonly associated with pulmonary hypoplasia and cardiac malformations. Some investigators hypothesize that this constellation of defects results from genetic or environmen
Autor:
Susanna Mannisto, Zsolt Urban, Jonathan M. Erlich, Markku Heikinheimo, Malgorzata Bielinska, Patrick Y. Jay, David B. Wilson
Publikováno v:
Annals of Medicine. 39:261-274
Congenital diaphragmatic hernia (CDH) is a severe birth defect that is accompanied by malformations of the lung, heart, testis, and other organs. Patients with CDH may have any combination of these extradiaphragmatic defects, suggesting that CDH is o
Autor:
Mikko Anttonen, David B. Wilson, Antti Kyrönlahti, Olli Ritvos, Markku Heikinheimo, Malgorzata Bielinska, Helka Parviainen
Publikováno v:
Journal of Molecular Endocrinology. 36:557-568
Part of heterodimeric inhibin, inhibin-α is crucial for mammalian ovarian function. Regulation of inhibin-α expression in granulosa cells is both endocrine, primarily by follicle-stimulating hormone (FSH), and paracrine, primarily by members of the
Autor:
Helka Parviainen, Sanne Kiiveri, Malgorzata Bielinska, Markku Heikinheimo, David B. Wilson, Susanna Mannisto
Publikováno v:
Veterinary Pathology. 43:97-117
Sex steroid-producing adrenocortical adenomas and carcinomas occur frequently in neutered ferrets, but the molecular events underlying tumor development are not well understood. Prepubertal gonadectomy elicits similar tumors in certain inbred or gene
Publikováno v:
Developmental Dynamics. 236:203-213
The transcription factor GATA-4 is expressed in Sertoli cells, steroidogenic Leydig cells, and other testicular somatic cells. Previous studies have established that interaction between GATA-4 and its cofactor FOG-2 is necessary for proper Sry expres
Autor:
Malgorzata Bielinska, Irving Boime, Elena Genova, David B. Wilson, Helka Parviainen, Nafis A. Rahman, Sanne Kiiveri, Markku Heikinheimo, Juhani Leppäluoto
Publikováno v:
Endocrinology. 146:3975-3984
In response to prepubertal gonadectomy certain inbred mouse strains, including DBA/2J, develop sex steroid-producing adrenocortical neoplasms. This phenomenon has been attributed to a lack of gonadal hormones or a compensatory increase in gonadotropi
Publikováno v:
Pediatric Research. 54:542-546
Transcription factors GATA-4 and GATA-6 play critical roles in mammalian yolk sac differentiation and function. Previously, we showed that GATA-4 is a potential marker for malignant yolk sac endoderm in pediatric germ cell tumors. This highly maligna
Autor:
Nafis A. Rahman, Elena Genova, Louis J. Muglia, David B. Wilson, Susan B. Porter-Tinge, Ilpo Huhtaniemi, Sanne Kiiveri, Malgorzata Bielinska, Helka Parviainen, Markku Heikinheimo
Publikováno v:
Endocrinology. 144:4123-4133
Certain inbred strains of mice, including DBA/2J, develop adrenocortical tumors in response to gonadectomy. Spindle-shaped cells with limited steroidogenic capacity, termed A cells, appear in the subcapsular region of the adrenal gland, followed by s