The pharmacokinetics, safety, and tolerability of mirabegron in children and adolescents with neurogenic detrusor overactivity or idiopathic overactive bladder and development of a population pharmacokinetic model-based pediatric dose estimation

Autor: Camilla Tøndel, Paul Passier, Otto Stroosma, Malgorzata Baka-Ostrowska, Søren Rittig, Brigitte Bosman, Birgitta Kjaeer, Stacey Tannenbaum, Johan Vande Walle

Publikováno v: Rittig, S, Baka-Ostrowska, M, Tøndel, C, Walle, J V, Kjaeer, B, Passier, P, Bosman, B, Stroosma, O & Tannenbaum, S 2020, ' The pharmacokinetics, safety, and tolerability of mirabegron in children and adolescents with neurogenic detrusor overactivity or idiopathic overactive bladder and development of a population pharmacokinetic model-based pediatric dose estimation ', Journal of Pediatric Urology, vol. 16, no. 1, pp. 31.e1-31.e10 . https://doi.org/10.1016/j.jpurol.2019.10.009
Journal of Pediatric Urology

Introduction: Mirabegron, a selective β3-adrenoreceptor agonist, is a well-established alternative to antimuscarinics in adults with overactive bladder (OAB) symptoms and is under development for use in pediatric patients. Understanding drug pharmac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::936a5f263f3784a0d3d6b45374b049de
https://pure.au.dk/portal/da/publications/the-pharmacokinetics-safety-and-tolerability-of-mirabegron-in-children-and-adolescents-with-neurogenic-detrusor-overactivity-or-idiopathic-overactive-bladder-and-development-of-a-population-pharmacokinetic-modelbased-pediatric-dose-estimation(ef3ee9a0-9ef8-4f65-bbad-09ad22a6d4bc).html

The risk of neoplasm associated with dysgenetic testes in prepubertal and pubertal/adult patients

Autor: Krzysztof Kula, Jerzy Niedzielski, Jan Karol Wolski, Katarzyna Marchlewska, Elżbieta Oszukowska, Jolanta Słowikowska-Hilczer, Maciej Hilczer, Malgorzata Baka-Ostrowska, Bogdan Kałużewski, Maria Szarras-Czapnik, Eliza Filipiak, Renata Walczak-Jędrzejowska, Lucjusz Jakubowski

Publikováno v: Folia Histochemica et Cytobiologica. 53:218-226

Introduction. In patients with Y-chromosome in the karyotype, partial gonadal dysgenesis and disorders of male reproductive sex organs development are usually resected in childhood because of the high risk of germ cell tumours (GCT). In patients with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17711ffae46903e3f74b90ca5186227c
https://doi.org/10.5603/fhc.a2015.0021

Temporary High Urinary Diversion with Valves Incision in the Same Procedure in Treatment of the Boys with Posterior Urethral Valves – 10 Years After

Autor: Piotr Gastol, Lidia Skobejko-Wlodarska, Malgorzata Baka-Ostrowska

Publikováno v: Journal of Pediatric Urology. 6:S49

Purpose There is a controversy regarding high urinary diversion in boys with posterior urethral valves (puv), because of the fear about bladder and upper urinary tract function after closure of the ureterocutaneostomy. We evaluated patients with puv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d1fec6c1cad58a0cf34ae92e24e7f1fc
https://doi.org/10.1016/j.jpurol.2010.02.079