Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Malene Watzinger"'
Autor:
Roy Forster, Rafif Dagher, Malene Watzinger, Catherine Thirion-Delalande, Guillaume Chevalier, Frederic Gervais
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 73(1)
Eliglustat is a novel glucosylceramide synthase inhibitor for long-term oral treatment of type 1 Gaucher disease (GD1), an inherited metabolic disorder. The carcinogenic potential of this drug has been evaluated in lifetime carcinogenicity bioassays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d42e7bdb281e7c7e56da0915d450db6
https://pubmed.ncbi.nlm.nih.gov/26232705
https://pubmed.ncbi.nlm.nih.gov/26232705
Publikováno v:
Journal of photochemistry and photobiology. B, Biology. 95(3)
The bifunctional furocoumarin 8-methoxypsoralen (8-MOP) is a well established drug in the photochemotherapy of psoriasis and other skin diseases. In eukaryotic cells, this compound intercalates into DNA and undergoes photocycloaddition with pyrimidin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd9b7276c919a28c39831a4c48b1adb
https://pubmed.ncbi.nlm.nih.gov/19318276
https://pubmed.ncbi.nlm.nih.gov/19318276
Publikováno v:
Environmental and molecular mutagenesis. 49(6)
The chelating agent nitrilotriacetic acid (NTA), classified as an epigenetic rodent carcinogen, was assessed in the in vivo rodent Comet assay on isolated kidney cells. Unexpected potent increases in DNA damage were obtained in both the short (3-6 hr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dcca08f5d43c665389484a10813b1f8
https://pubmed.ncbi.nlm.nih.gov/18449932
https://pubmed.ncbi.nlm.nih.gov/18449932
Publikováno v:
Toxicology Letters. 221:S70
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67f6cc61fa125bf951a2612684cea5c9
https://doi.org/10.1016/j.toxlet.2013.05.050
https://doi.org/10.1016/j.toxlet.2013.05.050