Insulin resistance in people living with HIV is associated with exposure to thymidine analogues and/or didanosine and prior immunodeficiency

Autor: Julie Høgh, Malene Hove-Skovsgaard, Marco Gelpi, Anne Marie Reimer Jensen, Jan Gerstoft, Thomas Benfield, Heidi Storgaard, Susanne Dam Nielsen

Publikováno v: BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-6 (2022)

Abstract Background As people living with HIV (PLWH) are growing older, there is increased incidence of metabolic diseases, including type 2 diabetes mellitus, for which insulin resistance is a key determinant. In this study, we aimed to investigate

Externí odkaz: https://doaj.org/article/fcbf85c90967444eaf90c18d32b47206

Improved induced innate immune response after cART initiation in people with HIV

Autor: Malene Hove-Skovsgaard, Dina Leth Møller, Annemette Hald, Jan Gerstoft, Jens Lundgren, Sisse Rye Ostrowski, Susanne Dam Nielsen

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

IntroductionImpairment of the innate immune function may contribute to the increased risk of bacterial and viral infections in people with HIV (PWH). In this study we aimed to investigate the induced innate immune responses in PWH prior to and after

Externí odkaz: https://doaj.org/article/34b3fd4c8bbd48cba4b6a433425e9d57

Impact of HIV and Type 2 diabetes on Gut Microbiota Diversity, Tryptophan Catabolism and Endothelial Dysfunction

Autor: Hedda Hoel, Malene Hove-Skovsgaard, Johannes R. Hov, Julie Christine Gaardbo, Kristian Holm, Martin Kummen, Knut Rudi, Felix Nwosu, Jørgen Valeur, Marco Gelpi, Ingebjørg Seljeflot, Per Magne Ueland, Jan Gerstoft, Henrik Ullum, Pål Aukrust, Susanne Dam Nielsen, Marius Trøseid

Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)

Abstract HIV infection and type 2 diabetes are associated with altered gut microbiota, chronic inflammation, and increased cardiovascular risk. We aimed to investigate the combined effect of these diseases on gut microbiota composition and related me

Externí odkaz: https://doaj.org/article/eddc42361c83490db0116a19884a4ca5

HIV Infection Is Associated With Type 2 Diabetes Mellitus

Autor: Thomas Benfield, Børge G. Nordestgaard, Julie Høgh, Marco Gelpi, Shoaib Afzal, Jan Gerstoft, Malene Hove-Skovsgaard, Heidi Storgaard, Susanne Dam Nielsen

Publikováno v: Journal of acquired immune deficiency syndromes (1999). 88(4)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9f662184b990de42d9ea3651b080e60
https://pubmed.ncbi.nlm.nih.gov/34520442

CCL1 and IL-2Ra differentiate Tuberculosis disease from latent infection Irrespective of HIV infection in low TB burden countries

Autor: Susanne Dam Nielsen, Kristian Tonby, Candice I. Snyders, Anne Ma Dyrhol-Riise, Synne Jenum, Novel N. Chegou, Malene Hove-Skovsgaard, Hallgeir Tveiten, Bih H. Chendi, Gerhard Walzl

Publikováno v: Chendi, B H, Tveiten, H, Snyders, C, Tonby, K, Jenum, S, Nielsen, S D, Hove-Skovsgaard, M, Walzl, G, Chegou, N N & Dyrhol-Riise, A M 2021, ' CCL1 and IL-2Ra differentiate Tuberculosis disease from latent infection Irrespective of HIV infection in low TB burden countries ', Journal of Infection, vol. 83, no. 4, pp. 433-443 . https://doi.org/10.1016/j.jinf.2021.07.036

Objectives: To evaluate the performance of selected host immunological biomarkers in differentiating tuberculosis (TB) disease from latent TB infection (LTBI) in HIV uninfected and infected individuals enrolled in TB low-burden countries.Design: Part

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83b25724b0e528cbaefc35e5709bc8f2
https://pubmed.ncbi.nlm.nih.gov/34333033