Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Malek A. Zihlif"'
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundHypoxia plays a critical role in the tumor microenvironment by affecting cellular proliferation, metabolism, apoptosis, DNA repair, and chemoresistance. Since hypoxia provokes a distinct shift of microRNA, it is important to illustrate the
Externí odkaz:
https://doaj.org/article/0d6817f0ffd5488086ee847ea5f2482f
Autor:
Justin Z. Amarin, Randa G. Naffa, Haya H. Suradi, Yousof M. Alsaket, Nathir M. Obeidat, Tareq M. Mahafza, Malek A. Zihlif
Publikováno v:
BMC Medical Genetics, Vol 18, Iss 1, Pp 1-6 (2017)
Abstract Background Asthma and allergic rhinitis are respiratory diseases with a significant global burden. Forkhead box O3 (FOXO3) is a gene involved in the etiology of a number of respiratory diseases. The objective of this study is to assess the a
Externí odkaz:
https://doaj.org/article/cbb0b7e8746d4ade854ddd74dc3e1b26
Autor:
Fuad M. Alhawarat, Hana M. Hammad, Majd S. Hijjawi, Ahmad S. Sharab, Duaa A. Abuarqoub, Mohammad A. Al Shhab, Malek A. Zihlif
Publikováno v:
PeerJ, Vol 7, p e5990 (2019)
Background Breast cancer is the most common type of cancer among females. Hypoxia mediates cancer hallmarks and results from reduced oxygen level due to irregularities in tumor vascularization or when the tumor size prevents oxygen diffusion and trig
Externí odkaz:
https://doaj.org/article/9a1e9fd0ac464920bc1c4d0c53d7af98
Autor:
Maysaa M. Saleh, Amjad N. Abuirmeileh, Rabaa M. Al-Rousan, Suha M. Abudoleh, Loay K. Hassouneh, Malek A. Zihlif, Mutasem O. Taha, Reem F. Abutayeh, Hebah Mansour, Bashaer Abu-Irmaileh
Publikováno v:
The Open Medicinal Chemistry Journal. 16
Here, we describe further cytotoxic studies and reverse pharmacophore mapping (pharmacophore profiling) for bis-triazoles MS44-53, which were designed and synthesized previously to stabilize the G-quadruplex nucleic acids capable of being formed at t
Autor:
Mohammad S. Mubarak, Randa G. Naffa, Ehab Q. Al-Momani, Malek A. Zihlif, Eman D. Awad, Suzan Matar, Mustafa M. El-Abadelah
Publikováno v:
Molecules, Vol 17, Iss 1, Pp 227-239 (2011)
A new series of 6-substituted-4-methyl-3-(4-arylpiperazin-1-yl)cinnolines 8–10 were synthesized as potential antifungal agents via intramolecular cyclization of the respective 1-(2-arylhydrazono)-1-(4-arylpiperazin-1-yl)propan-2-ones 5–7, mediate
Externí odkaz:
https://doaj.org/article/320d1fab1d8b4141b0b7e684c3f351e0
Autor:
Mohammad S. Mustafa, Mustafa M. El-Abadelah, Malek A. Zihlif, Randa G. Naffa, Mohammad S. Mubarak
Publikováno v:
Molecules, Vol 16, Iss 5, Pp 4305-4317 (2011)
A series of new N1-(coumarin-7-yl)amidrazones incorporating N-piperazines and related congeners were synthesized by reacting the hydrazonoyl chloride derived from 7-amino-4-methylcoumarin with the appropriate piperazines. The chemical structures of t
Externí odkaz:
https://doaj.org/article/5fa64f320dc34e1ba681ae59f8ccbffe
Autor:
Ismail F. Abaza, Zeyad D. Nassar, Malek Al-Zihlif, Aman A Ishaqat, Hana Hammad, Fatma U. Afifi, Rana Abu-Dahab
Publikováno v:
Natural Products Chemistry & Research.
Elaeagnus angustifolia L. has a long history of use in ethnopharmacology. Only few studies examined the potential activities of the leaves. Furthermore, the leaves’ chemical composition was not fully investigated. In this study, the chemical compos
Autor:
Almeqdad Y, Habashneh, Mustafa M, El-Abadelah, Malek A, Zihlif, Amer, Imraish, Mutasem O, Taha
Publikováno v:
Archiv der Pharmazie. 347(6)
A new series of N1-(flavon-6-yl)amidrazones were synthesized by reacting the hydrazonoyl chloride derived from 6-aminoflavone with the appropriate sec-cyclic amines. The antitumor activities of these compounds were evaluated on breast cancer (MCF-7)
Autor:
AL-MTERIN, Mohammad A.1, ABOALHAIJA, Nour2, ZIHLIF, Malek A.1, AFIFI, Fatma U.3,4 fatueafi@ju.edu.jo
Publikováno v:
Journal of Research in Pharmacy. 2024, Vol. 28 Issue 1, p278-288. 11p.
Publikováno v:
Frontiers in Endocrinology; 2023, p1-16, 16p