Characteristics of the cytoplasmic halo during fertilisation correlate with the live birth rate after fresh cleaved embryo transfer on day 2 in minimal ovarian stimulation cycles: a retrospective observational study

Autor: Tamotsu Kobayashi, Tadashi Okimura, Kazuo Uchiyama, Kenji Ezoe, Tetsuya Miki, Akiko Yabuuchi, Keiichi Kato

Publikováno v: Reproductive Biology and Endocrinology, Vol 19, Iss 1, Pp 1-10 (2021)
Reproductive Biology and Endocrinology : RB&E

Background Information regarding the influence of cytoplasmic events during fertilisation on the clinical outcome remains limited. The cytoplasmic halo is one of these events. A previous study that used time-lapse technology found an association of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::195f57abc8ce62be87f79a0a6308d69b
https://doaj.org/article/61985a4a82f446baa620f3c4ae3a891f

PRC2 and EHMT1 regulate H3K27me2 and H3K27me3 establishment across the zygote genome

Autor: Yi Hou, Xiaoyu Liu, Honglin Liu, Ying-Chun Ouyang, Qing-Yuan Sun, Zheng-Hui Zhao, Xue-Shan Ma, Xiang-Hong Ou, Wen-Long Lei, Shaorong Gao, Tie-Gang Meng, Zhen-Bo Wang, Xian-Ju Huang, Qing-Ren Meng, Qian Zhou, Heide Schatten

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications

The formation of zygote is the beginning of mammalian life, and dynamic epigenetic modifications are essential for mammalian normal development. H3K27 di-methylation (H3K27me2) and H3K27 tri-methylation (H3K27me3) are marks of facultative heterochrom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfe28d0a6a7dd5b17e4678594191521b
https://doaj.org/article/880e838cf60f4e349e02ecc7127b2eb6

EFFECTS OF DIFFERENT DURATION OF CO-INCUBATION OF GAMETES ON THE DEVELOPMENT OF SHEEP EMBRYOS

Autor: Cedden, F., Hafedh, S., Ushakov, A.

The stage of in vitro fertilization (IVF) is considered as a pivotal term in the embryo production programs in mammals, although the effect of this stage is still underestimated, especially in sheep. In IVF laboratories, oocytes are exposed to sperma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d0c853b2d4451cf4b983b4ed49067eef

Fertilization and Cleavage Axes Differ In Primates Conceived By Conventional (IVF) Versus Intracytoplasmic Sperm Injection (ICSI)

Autor: Carrie Hartnett, Gerald Schatten, Calvin Simerly, Carlos A. Castro, Laura Hewitson, Ethan Jacoby, Diana Takahashi, Christopher S. Navara

Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports

With nearly ten million babies conceived globally, using assisted reproductive technologies, fundamental questions remain; e.g., How do the sperm and egg DNA unite? Does ICSI have consequences that IVF does not? Here, pronuclear and mitotic events in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb4d0a5899d469c00be233f8259dcb80
https://doaj.org/article/936b0f4f351b4142b33f5458069f4be0

HIRA contributes to zygote formation in mice and is implicated in human 1PN zygote phenotype

Autor: Richard A. Anderson, Anna Kopakaki, Chih-Jen Lin, Kj Thong, Susan J Pickering, Rowena Smith

Publikováno v: Smith, R, Pickering, S J, Kopakaki, A, Thong, K, Anderson, R A & Lin, C 2021, ' HIRA contributes to zygote formation in mice and is implicated in human 1PN zygote phenotype ', Reproduction . https://doi.org/10.1530/REP-20-0636
Reproduction (Cambridge, England)

Elucidating the mechanisms underpinning fertilisation is essential to optimising IVF procedures. One of the critical steps involves paternal chromatin reprogramming, in which compacted sperm chromatin packed by protamines is removed by oocyte factors

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e7c8aa8ea2e7af39b49d99c06ee7e42
https://www.pure.ed.ac.uk/ws/files/216490874/_17417899_Reproduction_HIRA_contributes_to_zygote_formation_in_mice_and_is_implicated_in_human_1PN_zygote_phenotype.pdf