Zobrazeno 1 - 10
of 431
pro vyhledávání: '"Male germline"'
Publikováno v:
Journal of Functional Biomaterials, Vol 14, Iss 11, p 543 (2023)
Male germline stem cells (mGSCs), also known as spermatogonial stem cells (SSCs), are the fundamental seed cells of male animal reproductive physiology. However, environmental influences, drugs, and harmful substances often pose challenges to SSCs, s
Externí odkaz:
https://doaj.org/article/2996a71c8878479fa037013493933153
Autor:
Takaya Saito, Paul Whatmore, John F. Taylor, Jorge M. O. Fernandes, Anne-Catrin Adam, Douglas R. Tocher, Marit Espe, Kaja H. Skjærven
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-18 (2022)
Abstract Background DNA methylation has an important role in intergenerational inheritance. An increasing number of studies have reported evidence of germline inheritance of DNA methylation induced by nutritional signals in mammals. Vitamins and mine
Externí odkaz:
https://doaj.org/article/c515b966c51347a4add361302f03b90c
Autor:
Hua-Ming Xi, Yi-Jie Ren, Fa Ren, Yu Li, Tian-Yu Feng, Zhi Wang, Ye-Qing Du, Li-Kun Zhang, Jian-Hong Hu
Publikováno v:
Asian Journal of Andrology, Vol 24, Iss 1, Pp 5-14 (2022)
Continuous spermatogenesis depends on the self-renewal and differentiation of spermatogonial stem cells (SSCs). SSCs, the only male reproductive stem cells that transmit genetic material to subsequent generations, possess an inherent self-renewal abi
Externí odkaz:
https://doaj.org/article/b43e63132ef0497aaf5a0dd4725fc653
Akademický článek
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Autor:
Cameron Moshfegh, Sebastian G. Rambow, Seraina A. Domenig, Aldona Pieńkowska-Schelling, Ulrich Bleul, Viola Vogel
Publikováno v:
Stem Cell Research, Vol 61, Iss , Pp 102780- (2022)
Spermatogonial stem cells (SSCs) originate from gonocytes that differentiate from primordial germ cells (PGCs). In the developing mouse testis, expression of the gene LIM homeobox 1 (Lhx1) marks the most undifferentiated SSCs, which has not yet been
Externí odkaz:
https://doaj.org/article/8499e31469014b3c937d6f5e0708984d
Akademický článek
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Autor:
Sara Di Persio, Tobias Tekath, Lara Marie Siebert-Kuss, Jann-Frederik Cremers, Joachim Wistuba, Xiaolin Li, Gerd Meyer zu Hörste, Hannes C.A. Drexler, Margot Julia Wyrwoll, Frank Tüttelmann, Martin Dugas, Sabine Kliesch, Stefan Schlatt, Sandra Laurentino, Nina Neuhaus
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 9, Pp 100395- (2021)
Summary: Despite the high incidence of male infertility, only 30% of infertile men receive a causative diagnosis. To explore the regulatory mechanisms governing human germ cell function in normal and impaired spermatogenesis (crypto), we performed si
Externí odkaz:
https://doaj.org/article/69ff66c3292144e7a730709ca93d00b8
Publikováno v:
Journal of Animal Science and Biotechnology, Vol 10, Iss 1, Pp 1-18 (2019)
Abstract We are entering an exciting epoch in livestock biotechnology during which the fundamental approaches (such as transgenesis, spermatozoa cryopreservation and artificial insemination) will be enhanced based on the modern understanding of the b
Externí odkaz:
https://doaj.org/article/95c26608d25142efa8dca8a15a4c186a
Akademický článek
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Autor:
Andreas Prell, Mustafa Orkun Sen, Ramya Potabattula, Laura Bernhardt, Marcus Dittrich, Thomas Hahn, Martin Schorsch, Federica Zacchini, Grazyna Ewa Ptak, Heiner Niemann, Thomas Haaf
Publikováno v:
Cells, Vol 11, Iss 4, p 731 (2022)
A growing number of sperm methylome analyses have identified genomic loci that are susceptible to paternal age effects in a variety of mammalian species, including human, bovine, and mouse. However, there is little overlap between different data sets
Externí odkaz:
https://doaj.org/article/4367152f1c8348dabe97fabc4af7c547