Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Malcy Tarin"'
Autor:
Christine Canbezdi, Malcy Tarin, Alexandre Houy, Dorine Bellanger, Tatiana Popova, Marc-Henri Stern, Sergio Roman-Roman, Samar Alsafadi
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 1361-1370 (2021)
The hotspot mutations of SF3B1, the most frequently mutated splicing gene in cancers, contribute to oncogenesis by corrupting the mRNA splicing. Further SF3B1 mutations have been reported in cancers but their consequences remain unclear. Here, we scr
Externí odkaz:
https://doaj.org/article/f607c970912741d794008dc33b121ec4
Autor:
Malcy Tarin, Fariba Némati, Didier Decaudin, Christine Canbezdi, Benjamin Marande, Lisseth Silva, Héloïse Derrien, Aart G. Jochemsen, Sophie Gardrat, Sophie Piperno-Neumann, Manuel Rodrigues, Pascale Mariani, Nathalie Cassoux, Marc-Henri Stern, Sergio Roman-Roman, Samar Alsafadi
Publikováno v:
Cancers; Volume 15; Issue 8; Pages: 2280
Uveal Melanoma (UM) is a rare and malignant intraocular tumor with dismal prognosis. Even if radiation or surgery permit an efficient control of the primary tumor, up to 50% of patients subsequently develop metastases, mainly in the liver. The treatm
Autor:
Didier Decaudin, Estelle Frisch Dit Leitz, Fariba Nemati, Malcy Tarin, Adnan Naguez, Mohamed Zerara, Benjamin Marande, Raquel Vivet-Noguer, Ensar Halilovic, Claire Fabre, Aart Jochemsen, Sergio Roman-Roman, Samar Alsafadi
Publikováno v:
European Journal of Cancer. 184:199
Autor:
Sergio Roman-Roman, Samar Alsafadi, Benjamin Marande, Didier Decaudin, Adnan Naguez, Raquel Vivet-Noguer, Claire Fabre, Mohamed Zerara, Ensar Halilovic, Aart G. Jochemsen, Fariba Nemati, Estelle Frisch Dit Leitz, Malcy Tarin
Publikováno v:
European Journal of Cancer
European Journal of Cancer, Elsevier, 2020, 126, pp.93-103. ⟨10.1016/j.ejca.2019.12.012⟩
European Journal of Cancer, 126, 93-103. ELSEVIER SCI LTD
European Journal of Cancer, Elsevier, 2020, 126, pp.93-103. ⟨10.1016/j.ejca.2019.12.012⟩
European Journal of Cancer, 126, 93-103. ELSEVIER SCI LTD
Introduction: Uveal melanoma (UM) is a rare and malignant intraocular tumour with a dismal prognosis. Despite a good control of the primary tumour by radiation or surgery, up to 50% of patients subsequently develop metastasis for which no efficient t
Autor:
Raquel Vivet-Noguer, Malcy Tarin, Christine Canbezdi, Stephane Dayot, Lisseth Silva, Alexandre Houy, Sylvain Martineau, Virginie Mieulet, Géraldine Gentric, Damarys Loew, Bérangère Lombard, Fariba Nemati, Sophie Richon, Lea Guyonnet, Vincent Servois, Stephan Vagner, Marc-Henri Stern, Sergio Roman-Roman, Samar Alsafadi
Publikováno v:
Cancers; Volume 14; Issue 9; Pages: 2113
SF3B1 mutations are recurrent in cancer and result in aberrant splicing of a previously defined set of genes. Here, we investigated the fate of aberrant transcripts induced by mutant SF3B1 and the related functional consequences. We first demonstrate
Autor:
Raymond Barnhill, Steven van Laere, Peter Vermeulen, Sergio Roman-Roman, Sophie Gardrat, Samar Alsafadi, Malcy Tarin, Gabriel Champenois, André Nicolas, Alexandre Matet, Nathalie Cassoux, Vincent Servois, Manuel Rodrigues, Richard Scolyer, Alexander Lazar, Emanuela Romano, Sophie Piperno-Neumann, Pascale Mariani, Claire Lugassy
Publikováno v:
Laboratory investigation
The replacement and desmoplastic histopathological growth patterns (HGP) were studied in patients with uveal melanoma liver metastases (MUM). L1CAM and laminin vascular network were detected at the advancing front of the high-risk replacement HGP but
Autor:
Michele Cornella, Tatiana Popova, Dorine Bellanger, Joshua J. Waterfall, Michel Wassef, Stéphane Dayot, Erik Lehnert, Malcy Tarin, Alexandre Houy, Marc-Henri Stern, Samar Alsafadi, Sergio Roman-Roman
Publikováno v:
Oncogene
Oncogene, Nature Publishing Group, 2020, ⟨10.1038/s41388-020-01507-5⟩
Oncogene, Nature Publishing Group, 2020, ⟨10.1038/s41388-020-01507-5⟩
Genes involved in 3′-splice site recognition during mRNA splicing constitute an emerging class of oncogenes. SF3B1 is the most frequently mutated splicing factor in cancer, and SF3B1 mutants corrupt branchpoint recognition leading to usage of crypt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfabf97c011776718bf36c794d5c3053
https://hal.sorbonne-universite.fr/hal-02988069/document
https://hal.sorbonne-universite.fr/hal-02988069/document
Publikováno v:
Cancers, Vol 11, Iss 7, p 1019 (2019)
Cancers
Cancers
Uveal Melanoma (UM) is a rare and malignant intraocular tumor with dismal prognosis. Despite the efficient control of the primary tumor by radiation or surgery, up to 50% of patients subsequently develop metastasis, mainly in the liver. Once the tumo