Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Malcolm Walkinshaw"'
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Akademický článek
Multiple chemical scaffolds inhibit a promising Leishmania drug target
Autor: Malcolm Walkinshaw
Publikováno v: IUCrJ, Vol 1, Iss 4, Pp 202-203 (2014)
Externí odkaz: https://doaj.org/article/d94722aa820e42bb9316c993a4b07ae9
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2
Cyclosporins
Autor: HANS FLIRI, GOETZ BAUMANN, ALBERT ENZ, JUERG KALLEN, MARCEL LUYTEN, VINCENT MIKOL, RAO MOVVA, VALERIE QUESNIAUX, MAX SCHREIER, MALCOLM WALKINSHAW, ROLAND WENGER, GERHARD ZENKE, MAURO ZURINI
Publikováno v: Annals of the New York Academy of Sciences. 696:47-53
Cyclosporin A (Sandimmun) achieves immunosuppressive activity by complex formation with cyclophilin and subsequent binding of the binary complex to and inhibiting protein phosphatase 2B (calcineurin). Complexes of nonimmunosuppressive cyclophilin bin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d7f4eeba4416946c848ac6bbe945f441
https://doi.org/10.1111/j.1749-6632.1993.tb17141.x
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3
Absolute Configuration of 2-Substituted 2-Azabicyclo[2.2.1]hept-5-enes
Autor: Esteban Pombo-Villar, Jakob Boelsterli, Maria Magdalena Cid, Julien France, Beat Fuchs, Malcolm Walkinshaw, Hans-Peter Weber
Publikováno v: Helvetica Chimica Acta. 76:1203-1215
The diastereoisomeric 2-substituted 2-azabicyclo[2.2.1]hept-5-enes 2–4 were prepared by aza-Diels-Alder reaction of cyclopentadiene with the corresponding methaniminium ions. Their relative configurations were deduced using 1H, 1H-ROESY experiments
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::80e4625b50eb6734fe52c052932a324c
https://doi.org/10.1002/hlca.19930760307
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4
TWGDAM validation of the AmpFlSTR Profiler Plus and AmpFlSTR COfiler STR multiplex systems using capillary electrophoresis
Autor: Mj, Lafountain, Mb, Schwartz, Pa, Svete, malcolm walkinshaw, Buel E
Publikováno v: Europe PubMed Central
Prior to forensic implementation, a profiling system requires validation following the recommendations presented by the Technical Working Group on DNA Analysis Methods (TWGDAM). In this work two such systems, AmpFlSTR Profiler Plus and AmpFfSTR COfil
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c2221a13d98decfbfe3dbaf69c5bfa4a
https://pubmed.ncbi.nlm.nih.gov/11569564
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7
Cyclosporins. Structure-activity relationships
Autor: Fliri H, Baumann G, Enz A, Kallen J, Luyten M, Mikol V, Movva R, Quesniaux V, Schreier M, malcolm walkinshaw
Publikováno v: Europe PubMed Central
Cyclosporin A (Sandimmun) achieves immunosuppressive activity by complex formation with cyclophilin and subsequent binding of the binary complex to and inhibiting protein phosphatase 2B (calcineurin). Complexes of nonimmunosuppressive cyclophilin bin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::cc84d40ed8c63b5b703f62b0fec249ac
http://europepmc.org/abstract/med/8109856
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8
Characterization of dopamine receptor subtypes by comparative structure-activity relationships: dopaminomimetic activities and solid state conformation of monohydroxy-1,2,3,4,4a,5,10,10a-octahydrobenz[g]quinolines and its implications for a rotamer-based dopamine receptor model
Autor: Mp, Seiler, Markstein R, malcolm walkinshaw, Jj, Boelsterli
Publikováno v: Europe PubMed Central
A series of phenolic (cis)- and (trans)-1,2,3,4,4a,5,10,10a-octahydrobenz[g]quinolines were investigated in the D1 and D2 dopamine (DA) models, DA-sensitive adenylate cyclase and electrically evoked acetylcholine release, respectively, and were compa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d26efb4eed4d5cf265d3368284fc0b55
http://europepmc.org/abstract/med/2566903
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