Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Malcolm Stewart Buchanan"'
Autor:
Malcolm Stewart Buchanan
Publikováno v:
Chemistry Education Research and Practice. 16:552-560
Most Tanzanian Higher Education Institutes do not have the materials and technology to give students a significant practical experience in the sciences. In 2013 Tanzania was rated 159th out of 187 countries for ‘human development’ (United Nations
Publikováno v:
Journal of Chemical Education. 90:1325-1332
The ability of developing countries to provide a sound tertiary chemical education is a key ingredient to the improvement of living standards and economic development within these countries. However, teaching undergraduate experimental chemistry and
Autor:
William N. Charman, Ronald J. Quinn, Rohan A. Davis, Malcolm Stewart Buchanan, Vicky M. Avery, Susan A. Charman, Sandra Duffy, Karen L. White, Katherine T. Andrews, David Brian Camp, Michael D. Edstein, David M. Shackleford
Publikováno v:
Journal of Medicinal Chemistry. 55:5851-5858
A new bispyrroloiminoquinone alkaloid, tsitsikammamine C (1), displayed potent in vitro antimalarial activity with IC(50) values of 13 and 18 nM against chloroquine-sensitive (3D7) and chloroquine-resistant (Dd2) Plasmodium falciparum, respectively.
Autor:
Malcolm Stewart Buchanan
Publikováno v:
Scopus-Elsevier
Advances in science and technology confront us with many of the pressing questions and challenges of today. This article describes the course ‘Science, Faith and Culture’, a new course in the 2012–2013 Academic Year for the Faculty of Natural a
Autor:
Yunjiang Feng, Anthony R. Carroll, Liza Fernandez, Vicky M. Avery, Ronald J. Quinn, Malcolm Stewart Buchanan
Publikováno v:
Organic Letters. 11:329-332
With the aim of finding new natural product antimalarials, the novel indole alkaloids flinderole A-C were found to have selective antimalarial activities with IC(50) values between 0.15-1.42 microM. Flinderole A was isolated from the Australian plant
Autor:
Yunjiang Feng, Thomas Fex, Linda Öster, Anthony R. Carroll, Malcolm Stewart Buchanan, Ronald J. Quinn, Yafeng Xue, Vicky M. Avery, Michael F. Jobling, Johanna Deinum, Rohan A. Davis, Deborah Wessling, John N. A. Hooper
Publikováno v:
Journal of Medicinal Chemistry. 51:3583-3587
Bioassay-guided fractionation of a CH2Cl2/MeOH extract of the sponge Suberea clavata using the serine protease factor XIa to detect antithrombotic activity led to the isolation of the new marine natural products, clavatadines A and B. Clavatadines A
Autor:
Moana Simpson, Ronald J. Quinn, Edward G. Hyde, Malcolm Stewart Buchanan, Annette Edser, Anthony R. Carroll
Publikováno v:
Journal of Natural Products. 67:1291-1294
Three new marine natural products, dysinosins B-D (1-3), were isolated from the sponge Lamellodysidea chlorea and their structures determined by 1D and 2D NMR spectroscopy. These compounds are inhibitors of the blood coagulation cascade serine protea
Autor:
Rohan A. Davis, David Brian Camp, Sandra Duffy, Xinzhou Yang, Vicky M. Avery, Malcolm Stewart Buchanan, Ronald J. Quinn
Publikováno v:
Journal of Natural Products. 73:985-987
A drug discovery program aimed at identifying new antimalarial leads from a prefractionated natural product library has resulted in the identification of a new bromotyrosine alkaloid, psammaplysin G (1), along with the previously isolated compound, p
Autor:
Malcolm Stewart Buchanan, Michael F. Jobling, Anthony R. Carroll, Rohan A. Davis, Vicky M. Avery, John N. A. Hooper, Deborah Wessling, Ronald J. Quinn, Yunjiang Feng
Publikováno v:
Journal of Natural Products. 72:973-975
Three new marine alkaloids, clavatadines C-E (1-3), together with the three known compounds aerophobin 1 (4), purealdin L (5), and aplysinamisine II (6) were isolated from extracts of the sponge Suberea clavata by bioassay-guided fractionation using
Publikováno v:
Magnetic Resonance in Chemistry. 45:359-361
A new chlorotryptamine alkaloid, N-chloromethyl-N,N-dimethyltryptamine, was isolated from a methanol extract of the Chinese shrub Acacia confusa Merr., together with its known hallucinogenic analogues, N-methyltryptamine, N,N-dimethyltryptamine and N