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pro vyhledávání: '"Malcolm Pluskal"'
Publikováno v:
The Journal of the Acoustical Society of America. 141:3505-3505
Chromatographic purification of target biomolecules is an important downstream process step in the development of new therapeutic agents, such as antibodies. This step employs chromatographic processes, such as affinity separation utilizing Protein A
Autor:
Malcolm Pluskal, Shelagh Casey, Jonathan N. Kremsky, Steven A. Kates, Heather Perry-O'Keefe, Nanda D. Sinha
Publikováno v:
Tetrahedron Letters. 37:4313-4316
The synthesis of 1-phenylpyrazolin-5-one carboxylate esters of biotin and fluorescein and their specific reactivity with amines under mild conditions to label various synthetic biopolymers such as oligonucleotides, peptides and PNA's is described.