Výsledky vyhledávání - "Malcolm P. France"

Autor: Malcolm P. France, Simon A. Freeman Bain, Brett A. Lidbury

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3d0c5a1c7b6a0e97bee938a8fabd2fed
https://doi.org/10.1016/b978-0-12-813697-3.00010-x

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TNF Regulates Chemokine Induction Essential for Cell Recruitment, Granuloma Formation, and Clearance of Mycobacterial Infection

Autor: Daniel R. Roach, Andrew G. D. Bean, Caroline Demangel, Malcolm P. France, Helen Briscoe, Warwick J. Britton

Publikováno v: The Journal of Immunology. 168:4620-4627

Host immunity to mycobacterial infection is dependent on the activation of T lymphocytes and their recruitment with monocytes to form granulomas. These discrete foci of activated macrophages and lymphocytes provide a microenvironment for containing t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c23cfb64dfd68afa8176a50885fbcb6c
https://doi.org/10.4049/jimmunol.168.9.4620

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Impaired Thrombin Generation in β2-Glycoprotein I Null Mice

Autor: Yonghua Sheng, Stephen W. Reddel, Herbert Herzog, Ying Xia Wang, Tim Brighton, Malcolm P. France, Sarah A. Robertson, Steven A. Krilis

Publikováno v: Europe PubMed Central

Autoimmune antibodies to beta(2)-glycoprotein I (beta2GPI) have been proposed to be clinically relevant because of their strong association with thrombosis, miscarriage, and thrombocytopenia. By using a homologous recombination approach, beta2GPI-nul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c93272606316952429ee614ed41755c4
https://doi.org/10.1074/jbc.m010990200

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Structural Deficiencies in Granuloma Formation in TNF Gene-Targeted Mice Underlie the Heightened Susceptibility to Aerosol Mycobacterium tuberculosis Infection, Which Is Not Compensated for by Lymphotoxin

Autor: Andrew G. D. Bean, Daniel R. Roach, Helen Briscoe, Malcolm P. France, Heinrich Korner, Jonathon D. Sedgwick, Warwick J. Britton

Publikováno v: The Journal of Immunology. 162:3504-3511

TNF and lymphotoxin-α (LTα) may act at various stages of the host response to Mycobacterium tuberculosis. To dissect the effects of TNF independent of LTα, we have used C57BL/6 mice with a disruption of the TNF gene alone (TNF−/−). Twenty-one

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::64dec62d0b30c1cfbde83eb9ce464217
https://doi.org/10.4049/jimmunol.162.6.3504

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Legislation and Oversight of the Conduct of Research Using Animals: A Global Overview

Autor: Kathryn Bayne, Timothy H. Morris, Malcolm P. France

Publikováno v: The UFAW Handbook on the Care and Management of Laboratory and Other Research Animals

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::00a5aea06589513c6eaefafb13b7455d
https://doi.org/10.1002/9781444318777.ch8

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Large volume hepatic freezing: association with significant release of the cytokines interleukin-6 and tumor necrosis factor a in a rat model

Autor: Joachim K. Seifert, Malcolm P. France, Jing Zhao, Elaine J. Bolton, Ian Finlay, Theodor Junginger, David L. Morris

Publikováno v: World journal of surgery. 26(11)

Although cryotherapy of liver tumors is generally considered a safe procedure, a syndrome of coagulopathy and fatal multiorgan failure has been observed in some patients and is called the cryoshock phenomenon. Our aim was to establish an animal model

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a69a4ab5905899509877192e06acac
https://pubmed.ncbi.nlm.nih.gov/12297923

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