Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Malcolm M. Slaughter"'
Publikováno v:
Frontiers in Ophthalmology, Vol 3 (2023)
Retinal sensitivity to a variety of artificial sweeteners was tested by monitoring changes in internal free calcium in isolated retinal neurons using Fluo3. Several ligands, including aspartame and saccharin elevated internal free calcium. The effect
Externí odkaz:
https://doaj.org/article/d4a2918f366f422d92e5641b4198b671
Publikováno v:
Vision Research. 180:80-86
The skate retina provides a native all-rod retina suited for investigating a single type of photoreceptor regarding its properties and signaling to second order cells. Using the aspartate-induced isolated A-wave of the skate eyecup electroretinogram
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc5abbda1f65779bab8a42bd70217972
https://doi.org/10.1016/j.visres.2020.12.005
https://doi.org/10.1016/j.visres.2020.12.005
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129133 (2015)
One general categorization of retinal ganglion cells is to segregate them into tonically or phasically responding neurons, each conveying discrete aspects of the visual scene. Although best identified in the output signals of the retina, this distinc
Externí odkaz:
https://doaj.org/article/cd531785f6f140d6ab5e1d8794c8a8e7
Publikováno v:
Exp Biol Med (Maywood)
Degeneration of photoreceptors is a major cause of blindness. Identifying new methods for the generation of photoreceptors offers valuable options for a cell replacement therapy of blindness. Here, we show that primary adult human retinal pigmented e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed1f15908f54207e603670b2fbccc769
https://pubmed.ncbi.nlm.nih.gov/33070653
https://pubmed.ncbi.nlm.nih.gov/33070653
Publikováno v:
The Journal of Physiology. 596:3709-3724
Starburst amacrine cells release GABA and ACh. This study explores the coordinated function of starburst-mediated cholinergic excitation and GABAergic inhibition to bistratified retinal ganglion cells, predominantly direction-selective ganglion cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91c2fb667ddde6807a733a3b0d9f6c78
https://doi.org/10.1113/jp275073
https://doi.org/10.1113/jp275073
Autor:
Malcolm M. Slaughter, Jay Garaycochea
Publikováno v:
The Journal of Physiology. 594:5543-5554
KEY POINTS GABA is an inhibitory transmitter but can sometimes produce paradoxical excitatory effects through synaptic networks. We found a novel GABA-mediated excitation within a single retinal cell. It involves a chain of events from receptor stimu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b0b3cd705b4a7990336c67de48760c9
https://doi.org/10.1113/jp272374
https://doi.org/10.1113/jp272374
Publikováno v:
The Journal of physiology. 596(16)
KEY POINTS: Starburst amacrine cells release GABA and ACh. This study explores the coordinated function of starburst‐mediated cholinergic excitation and GABAergic inhibition to bistratified retinal ganglion cells, predominantly direction‐selectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::98067ab73cac5a3806671536eb33d1a9
https://pubmed.ncbi.nlm.nih.gov/29758086
https://pubmed.ncbi.nlm.nih.gov/29758086
Publikováno v:
Physiological Reports. 5
Ionotropic receptors are tightly regulated by second messenger systems and are often present along with their metabotropic counterparts on a neuron9s plasma membrane. This leads to the hypothesis that the two receptor subtypes can interact, and indee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7ec6cefbe5f270ea9b7ac797dc78a4a
https://doi.org/10.14814/phy2.13129
https://doi.org/10.14814/phy2.13129
Publikováno v:
Journal of Neurophysiology. 112:193-203
Glutamate release at bipolar to ganglion cell synapses activates NMDA and AMPA/kainic acid (KA) ionotropic glutamate receptors. Their relative strength determines the output signals of the retina. We found that this balance is tightly regulated by pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9339147afdf897ac5a947acb3828ebc
https://doi.org/10.1152/jn.00817.2013
https://doi.org/10.1152/jn.00817.2013
Autor:
Malcolm M. Slaughter, Yunbo Song
Publikováno v:
The Journal of Physiology. 588:4937-4949
GABAergic amacrine cell feedback to bipolar cells in retina has been described, activating both GABAA and GABAC receptors. We explored whether metabotropic GABAB receptors also participate in this feedback pathway. CGP55845, a potent GABAB receptor a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f805c55edfdb3bc68153f1482b0c0aad
https://doi.org/10.1113/jphysiol.2010.194233
https://doi.org/10.1113/jphysiol.2010.194233