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pro vyhledávání: '"Malcolm Kates"'
Autor:
Pankaj Pathak, Yotam Blech-Hermoni, Kalpana Subedi, Jessica Mpamugo, Charissa Obeng-Nyarko, Rachel Ohman, Ilda Molloy, Malcolm Kates, Jessica Hale, Stacey Stauffer, Shyam K. Sharan, Ami Mankodi
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Pathak et al. identify LDB3, a striated muscle PDZ-LIM protein, as a signaling adaptor in a major mechanosensor assembly through interactions with filamin C, HSPA8, and PKCα. When LDB3 is mutated, PKCα and TSC2-mTOR mediated homeostasis is impaired
Externí odkaz:
https://doaj.org/article/d4e302a88eb748a8be9622e9386d26e5
Autor:
Yotam Blech-Hermoni, Jessica Hale, Pankaj Pathak, Rachel Ohman, Malcolm Kates, Kalpana Subedi, Stacey Stauffer, Ilda Molloy, Jessica Mpamugo, Charissa Obeng-Nyarko, Shyam K. Sharan, Ami Mankodi
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Communications Biology
Communications Biology
Mechanical stress induced by contractions constantly threatens the integrity of muscle Z-disc, a crucial force-bearing structure in striated muscle. The PDZ-LIM proteins have been proposed to function as adaptors in transducing mechanical signals to
Autor:
Malcolm Kates, Hannah Hayward
Publikováno v:
HPHR Journal. 15
Global public health campaigns have made great strides in the treatment, prevention, and elimination of infectious diseases. Combined efforts of organizations like the World Health Organization (WHO), Rotary International, the United States Centers f