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pro vyhledávání: '"Malcolm J. Saxton"'
Autor:
Chuan Liu, Malcolm J. Saxton, Jean-François Focant, Michal Brokl, Juan Escobar-Arnanz, Benjamin Savareear, Chris J. Wright
Publikováno v:
Journal of Chromatography A. :105-115
A simple direct sample collection/dilution and introduction method was developed using quartz wool and Tenax/sulficarb sorbents for thermal desorption and comprehensive two-dimensional gas chromatography (TD-GC × GC) analyses of volatile organic com
Autor:
Birgitte Andersen, Karen A. Bunting, Karl Nicholls, Malcolm J. Saxton, Jason Cameron, Mikael B. Caspersen, Kenneth A. Howard, Matthias Kuhlmann
Publikováno v:
Caspersen, M B, Kuhlmann, M, Nicholls, K, Saxton, M J, Andersen, B, Bunting, K, Cameron, J & Howard, K 2017, ' Albumin-based drug delivery using cysteine 34 chemical conjugates; important considerations and requirements ', Therapeutic Delivery, vol. 8, no. 7 . https://doi.org/10.4155/tde-2017-0038
The long blood circulation time of albumin has been clinically utilized as a half-life extension technology for improved drug performance. The availability of one free thiol for site-selective chemical conjugation offers an alternative approach to cu
Autor:
Mikael B. Caspersen, Antoine Maruani, Eifion Robinson, Karl Nicholls, Malcolm J. Saxton, João P. Nunes, Stephen Caddick, James R. Baker, Vijay Chudasama, Maurício Morais, Mark E. B. Smith
Publikováno v:
Organic & Biomolecular Chemistry
Thiol-stable albumin biologics are enabled by controlled, quantitative hydrolysis of maleimide–albumin conjugates, i.e. with no retro-Michael.
Herein we report the use of bromomaleimides for the construction of stable albumin conjugates via co
Herein we report the use of bromomaleimides for the construction of stable albumin conjugates via co
Autor:
Philip Harvey Morton, Diane Wilkinson, Nina Ternes, Barbara Scheiber-Mojdehkar, Joanna Hay, Christopher John Arthur Finnis, Hans Goldenberg, Robert W. Evans, Malcolm J. Saxton, Neil Dodsworth, Darrell Sleep, Tom Payne, David Tooth
Publikováno v:
Microbial Cell Factories
Microbial Cell Factories, Vol 9, Iss 1, p 87 (2010)
Microbial Cell Factories, Vol 9, Iss 1, p 87 (2010)
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