Zobrazeno 1 - 10
of 329
pro vyhledávání: '"Malcolm J. Moore"'
Autor:
David F. Schaeffer, Daniel J. Renouf, Steven J.M. Jones, Marco A. Marra, Janessa Laskin, Steven Gallinger, Jennifer J. Knox, Faiyaz Notta, Andrew Metcalfe, Cassia Warren, Malcolm J. Moore, Andrew J. Mungall, Richard A. Moore, Grainne M. O'Kane, Michael K.C. Lee, Hui-Li Wong, Laura M. Williamson, Luka Culibrk, Robert E. Denroche, Gun Ho Jang, Steve E. Kalloger, James T. Topham, Joanna M. Karasinska
Heatmap showing median gene expression levels (z-score) of genes involved in various pathways related to cellular metabolism. For each gene, within each of the four metabolic subgroups, expression values were assessed for significant deviation from z
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::255304b0b5735c553afac65d00b14af1
https://doi.org/10.1158/1078-0432.22474190.v1
https://doi.org/10.1158/1078-0432.22474190.v1
Autor:
Scott Kopetz, Stanley R. Hamilton, Hagen F. Kennecke, Paul Waring, Chris J. O'Callaghan, Christos S. Karapetis, Malcolm J. Moore, John R. Zalcberg, Timothy Price, Frank Holtrup, Hannah Quinn, Daniel L. Edelstein, Derek J. Jonker, Dongsheng Tu, Anthony Dowers, Jonathan M. Loree
Supplemental Tables and Figure Caption
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5b2729e1f3b3fb50a9551f5cdff0d70
https://doi.org/10.1158/1078-0432.22478880.v1
https://doi.org/10.1158/1078-0432.22478880.v1
Autor:
Jennifer J. Knox, Steven Gallinger, Malcolm J. Moore, Julie M. Wilson, Faiyaz Notta, David Hedley, Neesha Dhani, Paul M. Krzyzanowski, Lee Timms, Jen Jen Yeh, Richard A. Moffitt, Ashton A. Connor, Spring Holter, Mathieu Lemire, Sangeet Ghai, John M.S. Bartlett, Ilinca M. Lungu, Danielle Pasternack, Faridah Mbabaali, Jessica K. Miller, Robert C. Grant, Shari Moura, Hamzeh Albaba, Grainne M. O'Kane, Amy Zhang, Dianne Chadwick, Sheng-Ben Liang, Bernadette Southwood, Sean Creighton, Anna Dodd, Gun-Ho Jang, Robert E. Denroche, Sandra E. Fischer, Kyaw L. Aung
Purpose: To perform real-time whole genome sequencing (WGS) and RNA sequencing (RNASeq) of advanced pancreatic ductal adenocarcinoma (PDAC) to identify predictive mutational and transcriptional features for better treatment selection.Experimental Des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dbe8fc5dfab94ff81688a693a53d954
https://doi.org/10.1158/1078-0432.c.6524567.v1
https://doi.org/10.1158/1078-0432.c.6524567.v1
Autor:
Scott Kopetz, Stanley R. Hamilton, Hagen F. Kennecke, Paul Waring, Chris J. O'Callaghan, Christos S. Karapetis, Malcolm J. Moore, John R. Zalcberg, Timothy Price, Frank Holtrup, Hannah Quinn, Daniel L. Edelstein, Derek J. Jonker, Dongsheng Tu, Anthony Dowers, Jonathan M. Loree
Supplemental Figure 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::082a795b700a781b2bbf2ea351e1df63
https://doi.org/10.1158/1078-0432.22478883.v1
https://doi.org/10.1158/1078-0432.22478883.v1
Autor:
Malcolm J. Moore, Alice Chen, Lisa Wang, Lillian Lourenco, Mary J. MacKenzie, Kiran Virik, Georg Bjarnason, Christian Kollmannsberger, Steven J. Cohen, Patricia A. Tang
PDF file - 34K, Relationship between the presence of grade 1 or greater hypertension and best response to aflibercept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4ae78505ae2efc14496493f66416890
https://doi.org/10.1158/1078-0432.22447487
https://doi.org/10.1158/1078-0432.22447487
Autor:
Jennifer J. Knox, Steven Gallinger, Malcolm J. Moore, Julie M. Wilson, Faiyaz Notta, David Hedley, Neesha Dhani, Paul M. Krzyzanowski, Lee Timms, Jen Jen Yeh, Richard A. Moffitt, Ashton A. Connor, Spring Holter, Mathieu Lemire, Sangeet Ghai, John M.S. Bartlett, Ilinca M. Lungu, Danielle Pasternack, Faridah Mbabaali, Jessica K. Miller, Robert C. Grant, Shari Moura, Hamzeh Albaba, Grainne M. O'Kane, Amy Zhang, Dianne Chadwick, Sheng-Ben Liang, Bernadette Southwood, Sean Creighton, Anna Dodd, Gun-Ho Jang, Robert E. Denroche, Sandra E. Fischer, Kyaw L. Aung
Supplementary Methods, Tables and Figures Supplementary Table 1: Summary of whole genome sequencing results including performance metrics and time to reporting (N=62). Supplementary Table 2: Summary of GATA6 RNA in situ results and its correlation wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35e10b211fb98f6ea7d8674050f196d6
https://doi.org/10.1158/1078-0432.22460684
https://doi.org/10.1158/1078-0432.22460684
Autor:
Scott Kopetz, Stanley R. Hamilton, Hagen F. Kennecke, Paul Waring, Chris J. O'Callaghan, Christos S. Karapetis, Malcolm J. Moore, John R. Zalcberg, Timothy Price, Frank Holtrup, Hannah Quinn, Daniel L. Edelstein, Derek J. Jonker, Dongsheng Tu, Anthony Dowers, Jonathan M. Loree
Purpose:Expanded RAS/BRAF mutations have not been assessed as predictive for single-agent cetuximab in metastatic colorectal cancer (mCRC), and low mutant allele frequency (MAF) mutations are of unclear significance. We aimed to establish cetuximab e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3493ab03c0ff06263423b1839a575e1e
https://doi.org/10.1158/1078-0432.c.6530073.v1
https://doi.org/10.1158/1078-0432.c.6530073.v1
Autor:
David F. Schaeffer, Daniel J. Renouf, Steven J.M. Jones, Marco A. Marra, Janessa Laskin, Steven Gallinger, Jennifer J. Knox, Faiyaz Notta, Andrew Metcalfe, Cassia Warren, Malcolm J. Moore, Andrew J. Mungall, Richard A. Moore, Grainne M. O'Kane, Michael K.C. Lee, Hui-Li Wong, Laura M. Williamson, Luka Culibrk, Robert E. Denroche, Gun Ho Jang, Steve E. Kalloger, James T. Topham, Joanna M. Karasinska
Supplemental Figures and Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3852df3a24dd1848e9274a2417b877d5
https://doi.org/10.1158/1078-0432.22474184
https://doi.org/10.1158/1078-0432.22474184
Autor:
Malcolm J. Moore, Alice Chen, Lisa Wang, Lillian Lourenco, Mary J. MacKenzie, Kiran Virik, Georg Bjarnason, Christian Kollmannsberger, Steven J. Cohen, Patricia A. Tang
Purpose: Aflibercept is a recombinant fusion protein of the VEGF receptor (VEGFR) 1 and VEGFR2 extracellular domains. We assessed the safety and efficacy of aflibercept in patients with metastatic colorectal cancer (MCRC) who had received at least on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ca2962bc273f825c420b63bed628bde
https://doi.org/10.1158/1078-0432.c.6521087.v1
https://doi.org/10.1158/1078-0432.c.6521087.v1
Autor:
David F. Schaeffer, Daniel J. Renouf, Steven J.M. Jones, Marco A. Marra, Janessa Laskin, Steven Gallinger, Jennifer J. Knox, Faiyaz Notta, Andrew Metcalfe, Cassia Warren, Malcolm J. Moore, Andrew J. Mungall, Richard A. Moore, Grainne M. O'Kane, Michael K.C. Lee, Hui-Li Wong, Laura M. Williamson, Luka Culibrk, Robert E. Denroche, Gun Ho Jang, Steve E. Kalloger, James T. Topham, Joanna M. Karasinska
Purpose:Identification of clinically actionable molecular subtypes of pancreatic ductal adenocarcinoma (PDAC) is key to improving patient outcome. Intertumoral metabolic heterogeneity contributes to cancer survival and the balance between distinct me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::567a86b02b800479c2151570d0cd44c6
https://doi.org/10.1158/1078-0432.c.6528713
https://doi.org/10.1158/1078-0432.c.6528713