Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Malcolm J Hetheridge"'
Autor:
Matthew J. Winter, Yosuke Ono, Jonathan S. Ball, Anna Walentinsson, Erik Michaelsson, Anna Tochwin, Steffen Scholpp, Charles R. Tyler, Steve Rees, Malcolm J Hetheridge, Mohammad Bohlooly-Y
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The clinical heterogeneity of heart failure has challenged our understanding of the underlying genetic mechanisms of this disease. In this respect, large-scale patient DNA sequencing studies have become an invaluable strategy for identifying potentia
Externí odkaz:
https://doaj.org/article/c5241e27f188422cbb46be887827542a
Autor:
Matthew G Baron, Kate S Mintram, Stewart F Owen, Malcolm J Hetheridge, A John Moody, Wendy M Purcell, Simon K Jackson, Awadhesh N Jha
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0168837 (2017)
At high internal doses, pharmaceuticals have the potential for inducing biological/pharmacological effects in fish. One particular concern for the environment is their potential to bioaccumulate and reach pharmacological levels; the study of these im
Externí odkaz:
https://doaj.org/article/c07eb662724a4ce5b583a6df843621e3
Autor:
Piotr Grabowski, Jonathan S. Ball, Joseph Pinion, Andrew D. Randall, Jeremy Metz, Will S. Redfern, Malcolm J. Hetheridge, Marc Goodfellow, Matthew J. Winter, Charles R. Tyler, Karen Tse, Aya Takesono, Anna Tochwin, Maciej Trznadel
Publikováno v:
British Journal of Pharmacology. 178:2671-2689
BACKGROUND AND PURPOSE Functional brain imaging using genetically encoded Ca2+ sensors in larval zebrafish is being developed for studying seizures and epilepsy as a more ethical alternative to rodent models. Despite this, few data have been generate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17f7ff4230befba435c0d0b1c1ff643e
https://doi.org/10.1111/bph.15458
https://doi.org/10.1111/bph.15458
Autor:
Matthew J, Winter, Yosuke, Ono, Jonathan S, Ball, Anna, Walentinsson, Erik, Michaelsson, Anna, Tochwin, Steffen, Scholpp, Charles R, Tyler, Steve, Rees, Malcolm J, Hetheridge, Mohammad, Bohlooly-Y
Publikováno v:
Frontiers in pharmacology. 13
The clinical heterogeneity of heart failure has challenged our understanding of the underlying genetic mechanisms of this disease. In this respect, large-scale patient DNA sequencing studies have become an invaluable strategy for identifying potentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::714cd5c47b669d1e2beb41755d92fc99
https://pubmed.ncbi.nlm.nih.gov/35548346
https://pubmed.ncbi.nlm.nih.gov/35548346
Autor:
Erik Michaëlsson, Anna Tochwin, Mohammad Bohlooly-Y, Charles R. Tyler, Anna Walentinsson, Steve Rees, Matthew J. Winter, Yosuke Ono, Jonathan S. Ball, Steffen Scholpp, Malcolm J. Hetheridge
The clinical heterogeneity of heart failure has challenged our understanding of the underlying genetic mechanisms of this disease. In this respect, large-scale patient DNA sequencing studies have become an invaluable strategy for identifying potentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85fa99e27c96662190aa4d7b94a570ec
https://doi.org/10.1101/2021.09.14.460241
https://doi.org/10.1101/2021.09.14.460241
Autor:
Jeremy Metz, Andrew D. Randall, Peter B. C. Matthews, Dylan Windell, Stewart F. Owen, Jonathan S. Ball, Joe Pinion, Matthew J. Winter, Charles R. Tyler, Julian Moger, Will S. Redfern, Malcolm J. Hetheridge, Jonathan T. Brown
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-5 (2018)
Scientific Reports
Scientific Reports
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4765fc4b09923fbf8fec1c62d74e5262
http://link.springer.com/article/10.1038/s41598-018-32731-5
http://link.springer.com/article/10.1038/s41598-018-32731-5
Autor:
Jonathan S. Ball, Jeremy Metz, Dylan Windell, Julian Moger, Stewart F. Owen, Andrew D. Randall, Joe Pinion, Malcolm J. Hetheridge, Jonathan T. Brown, Will S. Redfern, Charles R. Tyler, Matthew J. Winter, Peter B. C. Matthews
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Scientific Reports
Scientific Reports
Functional neuroimaging, using genetically-encoded Ca2+ sensors in larval zebrafish, offers a powerful combination of high spatiotemporal resolution and higher vertebrate relevance for quantitative neuropharmacological profiling. Here we use zebrafis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfb1291c5f8287478ebc4d383c12607d
http://link.springer.com/article/10.1038/s41598-017-06646-6
http://link.springer.com/article/10.1038/s41598-017-06646-6
Autor:
Awadhesh N. Jha, Wendy M. Purcell, Simon K. Jackson, Stewart F. Owen, Matthew G. Baron, A. John Moody, Malcolm J. Hetheridge, Kate S. Mintram
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 1, p e0168837 (2017)
PLoS ONE, Vol 12, Iss 1, p e0168837 (2017)
At high internal doses, pharmaceuticals have the potential for inducing biological/pharmacological effects in fish. One particular concern for the environment is their potential to bioaccumulate and reach pharmacological levels; the study of these im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37ec2de5fa4caca3df644b6c623861e1
http://europepmc.org/articles/PMC5207725
http://europepmc.org/articles/PMC5207725
The utility of combining an ultrasound probe with conventional electrochemical stripping methodology has been assessed for the mercury free determination of copper within industrial effluent. The introduction of an ultrasound field within the cell du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af23c8c92f547ec1809d3ce8e7542246
https://doi.org/10.1081/al-100107302
https://doi.org/10.1081/al-100107302
Autor:
Francois Balloux, Stewart F. Owen, Malcolm J. Hetheridge, David J. Hosken, Charles R. Tyler, Lisa K. Bickley, Gareth LePage, A. Ross Brown
Publikováno v:
Philosophical Transactions of the Royal Society B: Biological Sciences. 364:3377-3390
Exposure to environmental chemicals can have negative consequences for wildlife and even cause localized population extinctions. Resistance to chemical stress, however, can evolve and the mechanisms include desensitized target sites, reduced chemical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3d8e42dee36abdf044242456b90da7c
https://doi.org/10.1098/rstb.2009.0126
https://doi.org/10.1098/rstb.2009.0126