Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Malcolm Howard Wilkinson"'
Autor:
Vanessa J. Kelly, Philip J. Berger, Malcolm R. Davidson, Malcolm Howard Wilkinson, Scott A. Sands, Bradley A. Edwards
Publikováno v:
Journal of Theoretical Biology. 264:657-662
Ventilation–perfusion (V/Q) mismatch is a prominent feature of preterm infants and adults with lung disease. V/Q mismatch is known to cause arterial hypoxemia under steady-state conditions, and has been proposed as the cause of rapid arterial oxyge
Autor:
Philip J. Berger, Scott A. Sands, Malcolm Howard Wilkinson, Peter Camilleri, Gregory Keith Cambrell, Robin James Alfredson, Rebecca Breuer, Elizabeth M. Skuza
Publikováno v:
Journal of Sound and Vibration. 320:559-575
We describe a novel technique for direct measurement of the unloaded driving-point mechanical mobility of a structure. The method uses an electrically-excited inertial motor/actuator attached directly to the structure under test (SUT) to induce sinus
Autor:
John S. Wyatt, Adrian M. Walker, Topun Austin, Judith Meek, Flora Y. Wong, T.S. Leung, Malcolm Howard Wilkinson
Publikováno v:
Pediatrics. 121:e604-e611
OBJECTIVE. The absence of cerebral autoregulation in preterm infants has been associated with adverse outcome, but its bedside assessment in the immature brain is problematic. We used spatially resolved spectroscopy to continuously measure cerebral o
Autor:
Malcolm Howard Wilkinson, Rosemary S.C. Horne, Philip J. Berger, Stephanie Yiallourou, Scott A. Sands, Elizabeth M. Skuza, George C Rennie
Publikováno v:
Monash University
Previous studies of the maturation of periodic breathing cycle duration (PCD) with postnatal age in infants have yielded conflicting results. PCD is reported to fall in term infants over the first 6 mo postnatally, whereas in preterm infants PCD is r
Publikováno v:
The Journal of Physiology. 582:369-378
Arousal and cardio-respiratory responses to respiratory stimuli during sleep are important protective mechanisms that rapidly become depressed in the active sleep state when episodes of hypoxia or asphyxia are repeated: whether responses to repeated
Publikováno v:
Journal of Applied Physiology. 98:2235-2241
We measured the velocity and attenuation of audible sound in the isolated lung of the near-term fetal sheep to test the hypothesis that the acoustic properties of the lung provide a measure of the volume of gas it contains. We introduced pseudorandom
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 164:1019-1024
This study aimed to examine the performance characteristics of four high-frequency oscillatory-type ventilators, using an in vitro model of the intubated neonatal respiratory system. Each ventilator was examined across its operative range of settings
Publikováno v:
The Journal of Physiology. 510:651-659
1. Arousal from sleep is an important protective mechanism that is depressed by repeated episodes of hypoxia. We aimed to determine how rapidly arousal depression occurs during repeated hypoxia and to determine if the depression is sleep state specif
Publikováno v:
Brain Research. 612:299-305
The respiratory pattern generator in fetal and postnatal life activates the phrenic nucleus and diaghragm muscle with phasic bursts of activity. In the fetus, diaphragmatic activity is also characterized by tonic activity patterns of unknown origin.
Autor:
Malcolm R. Davidson, Malcolm Howard Wilkinson, Vanessa J. Kelly, Bradley A. Edwards, Scott A. Sands, Elizabeth M. Skuza, Philip J. Berger
Publikováno v:
American journal of respiratory and critical care medicine. 182(7)
Rationale: Brief recurrent apneas in preterm infants and adults can precipitate rapid and severe arterial O2 desaturation for reasons that remain unclear. Objectives: We tested a mathematically derived hypothesis that when breathing terminates apnea,