Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Malcolm D Ogilvie"'
Autor:
Patricia J Sollars, Michael J Weiser, Andrea E Kudwa, Jayne R Bramley, Malcolm D Ogilvie, Robert L Spencer, Robert J Handa, Gary E Pickard
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e111944 (2014)
The suprachiasmatic nucleus (SCN) is a circadian oscillator entrained to the day/night cycle via input from the retina. Serotonin (5-HT) afferents to the SCN modulate retinal signals via activation of 5-HT1B receptors, decreasing responsiveness to li
Externí odkaz:
https://doaj.org/article/76f039b039974d22beac66decdd773c5
Publikováno v:
PLoS ONE, Vol 4, Iss 3, p e4984 (2009)
Retinal ganglion cells that express the photopigment melanopsin are intrinsically photosensitive (ipRGCs) and exhibit robust synaptically driven ON-responses to light, yet they will continue to depolarize in response to light when all synaptic input
Externí odkaz:
https://doaj.org/article/39f4a50d92484d3bb53031d4388d85d6
Publikováno v:
Journal of Biological Rhythms. 21:21-32
The hypothalamic suprachiasmatic nucleus (SCN) is a circadian oscillator that receives glutamatergic afferents from the retina and serotonergic afferents from the midbrain. Activation of presynaptic serotonin 1B (5-HT1B) receptors on retinal terminal
Autor:
Malcolm D. Ogilvie, Cynthia A. Smeraski, Patricia J. Sollars, Lynn W. Enquist, Gary E. Pickard
Publikováno v:
The Journal of Comparative Neurology. 471:298-313
Intraocular injection of the Bartha strain of pseudorabies virus (PRV Bartha) results in transsynaptic infection of the hypothalamic suprachiasmatic nucleus (SCN), a retinorecipient circadian oscillator. PRV Bartha infection of a limited number of re
Publikováno v:
Journal of Biological Rhythms. 18:145-158
Serotonin (5-HT) is thought to play a role in regulating nonphotic phase shifts and modulating photic phase shifts of the mammalian circadian system, but results with different species (rats vs. hamsters) and techniques (in vivo vs. in vitro; systemi
Publikováno v:
Journal of Biological Rhythms. 17:428-437
Serotonin (5-HT) can act presynaptically at 5-HT1B receptors on retinal terminals in the suprachiasmatic nucleus (SCN) to inhibit glutamate release, thereby modulating the effects of light on circadian behavior. 5-HT1B receptor agonists (1) inhibit l
Autor:
Susan S. Margulies, Allan I. Pack, Michael J. Brennick, Luke Hiller, Malcolm D. Ogilvie, Warren B. Gefter
Publikováno v:
Journal of Applied Physiology. 85:1884-1897
Upper airway compliance indicates the potential of the airway to collapse and is relevant to the pathogenesis of obstructive sleep apnea. We hypothesized that compliance would vary over the rostral-to-caudal extent of the pharyngeal airway. In a para
Publikováno v:
NeuroReport. 7:1245-1248
Induced changes in the level of daily activity can alter the period of the mammalian circadian clock. In this report, we examined the period of the circadian rhythm of wheel-running activity in a transgenic neurological mouse mutant, Wocko. Wocko mic
Publikováno v:
NeuroReport. 7:529-533
We hypothesize that sleep homeostasis involves, at least in part, the immune system modulator interleukin-1 beta (IL-1 beta). Using the reverse transcription-polymerase chain reaction, IL-1 beta mRNA levels in the rat CNS were evaluated after a perio
Publikováno v:
Neural Computation. 6:56-68
To help evaluate the hypothesis that the central respiratory rhythm is generated by a network of interacting neurons, a network model of respiratory rhythmogenesis is formulated and examined computationally. The neural elements of the network are dri