Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Malcolm Brenner"'
Autor:
Nirali Shah, Lili Yang, Kasia Bourcier, Antoni Ribas, Pawel Kalinski, Ke Liu, Phil Greenberg, Carl June, Marcela Maus, Steven Rosenberg, Madhav Dhodapkar, Irina Tiper, Chantale Bernatchez, Michael Hudecek, Stanley Riddell, Stephen Gottschalk, Crystal Mackall, Lisa Butterfield, Greg Delgoffe, Michael Nishimura, Terry Fry, Marc S. Ernstoff, Christopher Klebanoff, Elad Sharon, Malcolm Brenner, Cliona Rooney, Christine Brown, Marc S Ernstoff, Tonya Webb, Magdalena Thurin, Wendell Lim, David Stroncek, Catherine Bollard, Helen Chen, Cameron Turtle, Christian Hinrichs, Laura K Fogli, Rosemarie Aurigemma, Connie L Sommers, Steven Albelda, Renier Brentjens, Yvonne Chen, Laronna Colbert, Kenneth Cornetta, Jason Cristofaro, Thomas Finn, Laura K Fogli Hunter, Alyssa Galaro, Ananda Goldrath, Ray Harris, Lori Henderson, Yuxia Jia, Dan Kaufman, Bruce Levine, Lawrence Lum, Samantha Maragh, Alex Marson, Raj Puri, Jake Reder, Isabelle Riviere, Kole Roybal, Rachelle Salomon, Tal Salz, Barbra Sasu, Andrea Schietinger, Connie L. Sommers, Minkyung Song, Fyodor Urnov, Anthony Welch, Travis Young, Jason Yovandich
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)
Cell-based immunotherapies have had remarkable success in the clinic, specifically in the treatment of hematologic malignancies. However, these strategies have had limited efficacy in patients with solid tumors. To better understand the challenges in
Externí odkaz:
https://doaj.org/article/f4500c9773db47d7abfb74eccac2d857
Autor:
Kenneth Cornetta, Jing Yao, Kimberley House, Lisa Duffy, Prasad S. Adusumilli, Rachel Beyer, Claire Booth, Malcolm Brenner, Kevin Curran, Bambi Grilley, Helen Heslop, Christian S. Hinrichs, Rosandra N. Kaplan, Hans-Peter Kiem, James Kochenderfer, Donald B. Kohn, Sham Mailankody, Scott M. Norberg, Roisin E. O'Cearbhaill, Jennifer Pappas, Jae Park, Carlos Ramos, Antonio Ribas, Isabelle Rivière, Steven A. Rosenberg, Craig Sauter, Nirali N. Shah, Susan F. Slovin, Adrian Thrasher, David A. Williams, Tsai-Yu Lin
Publikováno v:
Molecular Therapy. 31:801-809
The clinical impact of any therapy requires the product be safe and effective. Gammaretroviral vectors pose several unique risks, including inadvertent exposure to replication competent retrovirus (RCR) that can arise during vector manufacture. The U
Autor:
Premal D. Lulla, Malcolm Brenner
Publikováno v:
The Cancer Journal. 29:20-27
Publikováno v:
Holland‐Frei Cancer Medicine. :1-11
Autor:
Masataka Suzuki, Malcolm Brenner, Stephen Gottschalk, Bhakti Rana, Caroline Porter, Norihiro Watanabe, Amanda Rosewell Shaw, Kiyonori Tanoue
Supplemental Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd7aa0f2bf5927a38da08bcd558dc138
https://doi.org/10.1158/0008-5472.22416062.v1
https://doi.org/10.1158/0008-5472.22416062.v1
Autor:
Masataka Suzuki, Malcolm Brenner, Stephen Gottschalk, Bhakti Rana, Caroline Porter, Norihiro Watanabe, Amanda Rosewell Shaw, Kiyonori Tanoue
Supplemental Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f144d941554600dfc9bd2220af7a94c
https://doi.org/10.1158/0008-5472.22416065
https://doi.org/10.1158/0008-5472.22416065
Autor:
Masataka Suzuki, Malcolm Brenner, Stephen Gottschalk, Bhakti Rana, Caroline Porter, Norihiro Watanabe, Amanda Rosewell Shaw, Kiyonori Tanoue
Anti-PD-L1 antibody and PD-L1 mini-body enhance HER2.CAR T-cell proliferation in vitro.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f6fe3cf798e0e1f6797212bb3a71b48
https://doi.org/10.1158/0008-5472.22416077.v1
https://doi.org/10.1158/0008-5472.22416077.v1
Autor:
Masataka Suzuki, Malcolm Brenner, Stephen Gottschalk, Bhakti Rana, Caroline Porter, Norihiro Watanabe, Amanda Rosewell Shaw, Kiyonori Tanoue
PD-L1 mini-body is expressed at tumor site 10 days post-injection of HER2.CAR T-cells, but minimally impacts CD4+ T-cell phenotype long-term.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::498de7115f3e72e863d6a9c717d713dc
https://doi.org/10.1158/0008-5472.22416071.v1
https://doi.org/10.1158/0008-5472.22416071.v1
Autor:
Masataka Suzuki, Malcolm Brenner, Stephen Gottschalk, Bhakti Rana, Caroline Porter, Norihiro Watanabe, Amanda Rosewell Shaw, Kiyonori Tanoue
Chimeric antigen receptor–modified T cells (CAR T cells) produce proinflammatory cytokines that increase expression of T-cell checkpoint signals such as PD-L1, which may inhibit their functionality against solid tumors. In this study, we evaluated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ec227d82abb90c37da3cfe4b88b4b09
https://doi.org/10.1158/0008-5472.c.6509453
https://doi.org/10.1158/0008-5472.c.6509453
Autor:
Masataka Suzuki, Malcolm Brenner, Stephen Gottschalk, Bhakti Rana, Caroline Porter, Norihiro Watanabe, Amanda Rosewell Shaw, Kiyonori Tanoue
LD50 of Onc.Ad, HDAd or CAd-VEC in each cell line.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c45d779d2806ed48becf7ae7326cadc
https://doi.org/10.1158/0008-5472.22416059.v1
https://doi.org/10.1158/0008-5472.22416059.v1