Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Malcolm Boyce"'
Autor:
Ellen James, David Erritzoe, Tiffanie Benway, Zelah Joel, Christopher Timmermann, Meghan Good, Claudio Agnorelli, Brandon M. Weiss, Tommaso Barba, Graham Campbell, Michelle Baker Jones, Charlotte Hughes, Helen Topping, Malcolm Boyce, Carol Routledge
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2024)
BackgroundDue to their potential impact on mood and wellbeing there has been increasing interest in the potential of serotonergic psychedelics such as N,N-dimethyltryptamine (DMT) in the treatment of major depressive disorder (MDD).AimThe aim of Part
Externí odkaz:
https://doaj.org/article/cbee5c85655e4709bea07b04421d3db3
Autor:
Helen M. Reid, Mark Maginn, C. Michael Perkins, Eamon P. Mulvaney, Malcolm Boyce, Takahiro Yamamoto, B. Therese Kinsella
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: The thromboxane receptor (TP) antagonist NTP42 is in clinical development for treatment of cardiopulmonary diseases, such as pulmonary arterial hypertension. In this randomized, placebo-controlled Phase I clinical trial, NTP42, administer
Externí odkaz:
https://doaj.org/article/0f5c039ae81d445b8dcc7e543d329485
Autor:
Amandine Bernard, Mohamad Mroué, Sylvie Bourthoumieu, Malcolm Boyce, Laurence Richard, Franck Sturtz, Claire Demiot, Aurore Danigo
Publikováno v:
Pharmaceuticals, Vol 17, Iss 2, p 144 (2024)
Among the vinca-alkaloid class, vincristine is a potent chemotherapeutic agent with significant neurotoxic effects and is employed to address a wide spectrum of cancer types. Recently, the therapeutic potential of the cholecystokinin type 2 receptor
Externí odkaz:
https://doaj.org/article/0e39ca0e5f31463e81bc1e2f6a015c0f
Autor:
Katie A. Lloyd, Bryony N. Parsons, Michael D. Burkitt, Andrew R. Moore, Stamatia Papoutsopoulou, Malcolm Boyce, Carrie A. Duckworth, Klaire Exarchou, Nathan Howes, Lucille Rainbow, Yongxiang Fang, Claus Oxvig, Steven Dodd, Andrea Varro, Neil Hall, D. Mark Pritchard
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 1, Pp 113-132 (2020)
Background & Aims: In patients with autoimmune atrophic gastritis and achlorhydria, hypergastrinemia is associated with the development of type 1 gastric neuroendocrine tumors (gNETs). Twelve months of treatment with netazepide (YF476), an antagonist
Externí odkaz:
https://doaj.org/article/fa9e77fa8ab04349aa617d5d954be8d7
Autor:
Gary Burgess, Malcolm Boyce, Margaret Jones, Lars Larsson, Mark J. Main, Frazer Morgan, Peter Phillips, Alison Scrimgeour, Foteini Strimenopoulou, Pavan Vajjah, Miren Zamacona, Roger Palframan
Publikováno v:
EBioMedicine, Vol 35, Iss , Pp 67-75 (2018)
Background: Interleukin-13 (IL-13) is a key mediator of T-helper-cell-type-2 (Th-2)-driven asthma, the inhibition of which may improve treatment outcomes. We examined the safety, pharmacokinetics, pharmacodynamics, and immunogenicity of VR942, a dry-
Externí odkaz:
https://doaj.org/article/4112209b44a549208dede8f273b97447
Autor:
Andrew R Moore, Malcolm Boyce, Islay A Steele, Fiona Campbell, Andrea Varro, D Mark Pritchard
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76462 (2013)
INTRODUCTION:Autoimmune chronic atrophic gastritis (CAG) causes hypochlorhydria and hypergastrinaemia, which can lead to enterochromaffin-like (ECL) cell hyperplasia and gastric neuroendocrine tumours (type 1 gastric NETs). Most behave indolently, bu
Externí odkaz:
https://doaj.org/article/0286970c132c4b0e80f448babc93b471
Autor:
Andrew R. Moore, Malcolm Boyce, Islay A. Steele, Fiona Campbell, Andrea Varro, D. Mark Pritchard
Publikováno v:
PLoS ONE, Vol 8, Iss 11 (2013)
Externí odkaz:
https://doaj.org/article/ab672e535e7940b8be286fdde9c81769
Publikováno v:
Journal of Neuroendocrinology.
Autor:
Nina Stojcheva, Stacy Gladman, Marianne Soergel, Christof Zitt, Roxana Drake, Tony Lockett, Carine Marchand, Pierre Fustier, Vaia Stavropoulou, Elena Fernandez, Nathana Lopes Pettigiani, Kate Watkins, Adeep Puri, Randall Watson, Philippe Legenne, Michael T. Stumpp, Malcolm Boyce
Publikováno v:
British Journal of Clinical Pharmacology.