Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Malcolm, Horne"'
Publikováno v:
IEEE Transactions on Neural Systems and Rehabilitation Engineering, Vol 31, Pp 4839-4850 (2023)
The assessment of speech in Cerebellar Ataxia (CA) is time-consuming and requires clinical interpretation. In this study, we introduce a fully automated objective algorithm that uses significant acoustic features from time, spectral, cepstral, and no
Externí odkaz:
https://doaj.org/article/2a91b7da244744b6a7f64fd9b136a3eb
Autor:
Thang Ngo, Dinh C. Nguyen, Pubudu N. Pathirana, Louise A. Corben, Martin B. Delatycki, Malcolm Horne, David J. Szmulewicz, Melissa Roberts
Publikováno v:
IEEE Transactions on Neural Systems and Rehabilitation Engineering, Vol 30, Pp 803-811 (2022)
Cerebellar ataxia (CA) is concerned with the incoordination of movement caused by cerebellar dysfunction. Movements of the eyes, speech, trunk, and limbs are affected. Conventional machine learning approaches utilizing centralised databases have been
Externí odkaz:
https://doaj.org/article/e318fbaa449245ca82344995a8cc048b
Publikováno v:
Clinical Parkinsonism & Related Disorders, Vol 8, Iss , Pp 100179- (2023)
Objectives: The feasibility of measuring bradykinesia and chorea in Huntington's Disease using a wearable sensor system (Parkinson’s Kinetigraph: PKG) developed for measuring bradykinesia and dyskinesia in Parkinson’s Disease was assessed. Method
Externí odkaz:
https://doaj.org/article/2a713896b93b4b3487190b47655c2fcf
Autor:
Stephan Klatt, James D. Doecke, Anne Roberts, Berin A. Boughton, Colin L. Masters, Malcolm Horne, Blaine R. Roberts
Publikováno v:
npj Parkinson's Disease, Vol 7, Iss 1, Pp 1-14 (2021)
Abstract Characterisation and diagnosis of idiopathic Parkinson’s disease (iPD) is a current challenge that hampers both clinical assessment and clinical trial development with the potential inclusion of non-PD cases. Here, we used a targeted mass
Externí odkaz:
https://doaj.org/article/881b06762bce4c4c9997ee283c5ce1c1
Publikováno v:
Journal of NeuroEngineering and Rehabilitation, Vol 18, Iss 1, Pp 1-17 (2021)
Abstract Background Fluctuations in motor function in Parkinson’s Disease (PD) are frequent and cause significant disability. Frequently device assisted therapies are required to treat them. Currently, fluctuations are self-reported through diaries
Externí odkaz:
https://doaj.org/article/81630454679f454da767e4d159440759
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
ObjectivesThere are concerns regarding the accuracy of step count in Parkinson’s disease (PD) when wearable sensors are used. In this study, it was predicted that providing the normal rhythmicity of walking was maintained, the autocorrelation funct
Externí odkaz:
https://doaj.org/article/c8a8d670198f46f6aee708d6f64ec053
Publikováno v:
IEEE Access, Vol 9, Pp 135343-135353 (2021)
Background: Accurate and reliable prediction of changes in the severity of cerebellar ataxia (CA) will be necessary for trials of disease-modifying therapies. Cerebellar dysarthria (CD) is a common feature of CA. This study demonstrated that objectiv
Externí odkaz:
https://doaj.org/article/71c932b2dcca468788e1f62d7c4fa5d1
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
ObjectivesThe aim was to examine the role of sensor measurement in identifying and managing fluctuations in bradykinesia of Parkinson’s Disease.MethodClinical scales and data from wearable sensors obtained before and after optimization of treatment
Externí odkaz:
https://doaj.org/article/61cd6799bb6f4b018664eecb19f1bebe
Autor:
Jade E. Kenna, Eng Guan Chua, Megan Bakeberg, Alfred Tay, Sarah McGregor, Anastazja Gorecki, Malcolm Horne, Barry Marshall, Frank L. Mastaglia, Ryan S. Anderton
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Background: There has been increasing recognition of the importance of the gut microbiome in Parkinson’s disease (PD), but the influence of geographic location has received little attention. The present study characterized the gut microbiota and as
Externí odkaz:
https://doaj.org/article/394bda038c6b4117bac8e9330fc90019
Publikováno v:
Journal of NeuroEngineering and Rehabilitation, Vol 16, Iss 1, Pp 1-15 (2019)
Abstract Background Cerebellar damage can often result in disabilities affecting the peripheral regions of the body. These include poor and inaccurate coordination, tremors and irregular movements that often manifest as disorders associated with bala
Externí odkaz:
https://doaj.org/article/b3cf2c2b033a4520b0be2c3ea065db00