Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Malayannan, Subramaniam"'
Autor:
Kirsten G. M. Aspros, Jodi M. Carter, Tanya L. Hoskin, Vera J. Suman, Malayannan Subramaniam, Michael J. Emch, Zhenqing Ye, Zhifu Sun, Jason P. Sinnwell, Kevin J. Thompson, Xiaojia Tang, Esther P. B. Rodman, Xiyin Wang, Adam W. Nelson, Igor Chernukhin, Feda H. Hamdan, Elizabeth S. Bruinsma, Jason S. Carroll, Martin E. Fernandez-Zapico, Steven A. Johnsen, Krishna R. Kalari, Haojie Huang, Roberto A. Leon-Ferre, Fergus J. Couch, James N. Ingle, Matthew P. Goetz, John R. Hawse
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-15 (2022)
Abstract Triple Negative Breast Cancer (TNBC) accounts for 15–20% of all breast cancer cases, yet is responsible for a disproportionately high percentage of breast cancer mortalities. Thus, there is an urgent need to identify novel biomarkers and t
Externí odkaz:
https://doaj.org/article/cb14a3f8cc2f47efa372c800d589e31a
Autor:
Kirsten G. M. Aspros, Michael J. Emch, Xiyin Wang, Malayannan Subramaniam, Megan L. Hinkle, Esther P. B. Rodman, Matthew P. Goetz, John R. Hawse
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Triple negative breast cancer (TNBC) is an aggressive sub-type of the disease which accounts for a disproportionately high percentage of breast cancer morbidities and mortalities. For these reasons, a better understanding of TNBC biology is required
Externí odkaz:
https://doaj.org/article/02caffd096eb485c9156f9741c54c9a7
Autor:
Anthony A Ruberto, Aline Gréchez-Cassiau, Sophie Guérin, Luc Martin, Johana S Revel, Mohamed Mehiri, Malayannan Subramaniam, Franck Delaunay, Michèle Teboul
Publikováno v:
eLife, Vol 10 (2021)
The mammalian circadian timing system and metabolism are highly interconnected, and disruption of this coupling is associated with negative health outcomes. Krüppel-like factors (KLFs) are transcription factors that govern metabolic homeostasis in v
Externí odkaz:
https://doaj.org/article/fa08fc0906c94393808804c0ab741b9b
Autor:
Nadine Baroukh, Nathan Canteleux, Antoine Lefèvre, Camille Dupuy, Cécile Martias, Antoine Presset, Malayannan Subramaniam, John R. Hawse, Patrick Emond, Philippe Pouletaut, Sandrine Morandat, Sabine F. Bensamoun, Lydie Nadal-Desbarats
Publikováno v:
Metabolites, Vol 12, Iss 6, p 556 (2022)
The transcription factor Krüppel-like factor 10 (Klf10), also known as Tieg1 for TGFβ (Inducible Early Gene-1) is known to control numerous genes in many cell types that are involved in various key biological processes (differentiation, proliferati
Externí odkaz:
https://doaj.org/article/df3452c8521d491aae4c8884357bf112
Autor:
Shivani N Mann, Niran Hadad, Molly Nelson Holte, Alicia R Rothman, Roshini Sathiaseelan, Samim Ali Mondal, Martin-Paul Agbaga, Archana Unnikrishnan, Malayannan Subramaniam, John Hawse, Derek M Huffman, Willard M Freeman, Michael B Stout
Publikováno v:
eLife, Vol 9 (2020)
Metabolic dysfunction underlies several chronic diseases, many of which are exacerbated by obesity. Dietary interventions can reverse metabolic declines and slow aging, although compliance issues remain paramount. 17α-estradiol treatment improves me
Externí odkaz:
https://doaj.org/article/1b1546f66bc7437c80062d0bfab7f142
Autor:
Steven A. Johnsen, John R. Hawse, Volker Ellenrieder, Florian Wegwitz, Sankari Nagarajan, Ryan M. Naylor, Simon J. Baumgart, Kevin S. Pitel, Vijayalakshmi Kari, Malayannan Subramaniam, Vivek Kumar Mishra
TGFβ–SMAD signaling exerts a contextual effect that suppresses malignant growth early in epithelial tumorigenesis but promotes metastasis at later stages. Longstanding challenges in resolving this functional dichotomy may uncover new strategies to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2ea93e2aec49e7b5b8f0b925f2408da
https://doi.org/10.1158/0008-5472.c.6509624.v1
https://doi.org/10.1158/0008-5472.c.6509624.v1
Autor:
Steven A. Johnsen, John R. Hawse, Volker Ellenrieder, Florian Wegwitz, Sankari Nagarajan, Ryan M. Naylor, Simon J. Baumgart, Kevin S. Pitel, Vijayalakshmi Kari, Malayannan Subramaniam, Vivek Kumar Mishra
Description of Supplementary Figures 1-3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd7ee0d27b274efcb52f19c273a60287
https://doi.org/10.1158/0008-5472.22416707.v1
https://doi.org/10.1158/0008-5472.22416707.v1
Autor:
Steven A. Johnsen, John R. Hawse, Volker Ellenrieder, Florian Wegwitz, Sankari Nagarajan, Ryan M. Naylor, Simon J. Baumgart, Kevin S. Pitel, Vijayalakshmi Kari, Malayannan Subramaniam, Vivek Kumar Mishra
Supplementary Figure S1 KLF10 is recruited to, and suppresses the expression of the FOSB gene. Supplementary Figure S2 ChIP analysis of KLF10 occupancy on the SNAI2 gene upon in control and TGFβ-stimulated Panc1 cells. Supplementary Figure S3 Heatma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aaa4886c8d4fb5a086a981ed7f4559b
https://doi.org/10.1158/0008-5472.22416704
https://doi.org/10.1158/0008-5472.22416704
Autor:
Steven A. Johnsen, John R. Hawse, Volker Ellenrieder, Florian Wegwitz, Sankari Nagarajan, Ryan M. Naylor, Simon J. Baumgart, Kevin S. Pitel, Vijayalakshmi Kari, Malayannan Subramaniam, Vivek Kumar Mishra
Supplemental table S1 Primers for gene expression and ChIP analysis (5'-3' orientation)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d423ea880bb0873a95d7df6ce865b8
https://doi.org/10.1158/0008-5472.22416710.v1
https://doi.org/10.1158/0008-5472.22416710.v1
Autor:
Malek Kammoun, Lydie Nadal-Desbarats, Sandra Même, Aude Lafoux, Corinne Huchet, Géraldine Meyer-Dilhet, Julien Courchet, Frédéric Montigny, Frédéric Szeremeta, William Même, Vladimir Veksler, Jérôme Piquereau, Philippe Pouletaut, Malayannan Subramaniam, J. Hawse, Jean-Marc Constans, S Bensamoun
Publikováno v:
Journal of Biomedical Science and Engineering. 15:140-156
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::055766e1da6ba4ad00b36af328e4057c
https://doi.org/10.4236/jbise.2022.155014
https://doi.org/10.4236/jbise.2022.155014