Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Malate dehydrogenase 1"'
Autor:
Govind S. Gill, Michael C. Schultz
Publikováno v:
FASEB BioAdvances, Vol 4, Iss 11, Pp 709-723 (2022)
Abstract In solid organs, cells of the same “type” can vary in their molecular phenotype. The basis of this state variation is being revealed by characterizing cell features including the expression pattern of mRNAs and the internal distribution
Externí odkaz:
https://doaj.org/article/589e792984f7456bbe21df775c0f0f37
Akademický článek
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Autor:
Cristina Ortega-Ferrusola, Fernando J. Peña, Gemma Gaitskell-Phillips, Eva da Silva-Álvarez, María Concepción Robles Gil, J. Masot, Eloy Redondo, Francisco E. Martín-Cano, José M. Ortiz-Rodríguez
Publikováno v:
Theriogenology. 177:34-41
Seminal plasma proteins have important roles in sperm functionality, and different mechanisms including micro-vesicle transport of proteins are involved in the regulation of sperm biology. Due to the role of seminal plasma, we hypothesized that speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df3ae1ed17878c996d8485d6b827ba44
https://doi.org/10.1016/j.theriogenology.2021.10.007
https://doi.org/10.1016/j.theriogenology.2021.10.007
Autor:
Piet Borst
Publikováno v:
Iubmb Life
This article presents a personal and critical review of the history of the malate–aspartate shuttle (MAS), starting in 1962 and ending in 2020. The MAS was initially proposed as a route for the oxidation of cytosolic NADH by the mitochondria in Ehr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3c3cde61f1fea8a1d39f040a8e497d7
https://doi.org/10.1002/iub.2367
https://doi.org/10.1002/iub.2367
Akademický článek
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Autor:
Rajiv Bajracharya, Jae Geun Song, Kshitis Chandra Baral, Hyo-Kyung Han, Kyeong Lee, Minkyoung Kim, Godesi Sreenivasulu, Sang Hoon Lee
Publikováno v:
Pharmaceutics
Volume 13
Issue 8
Pharmaceutics, Vol 13, Iss 1142, p 1142 (2021)
Volume 13
Issue 8
Pharmaceutics, Vol 13, Iss 1142, p 1142 (2021)
AC1497 is an effective dual inhibitor of malate dehydrogenase 1 and 2 targeting cancer metabolism. However, its poor aqueous solubility results in low bioavailability, limiting its clinical development. This study was conducted to develop an effectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c723ecee41b4d5be76c2e6b06b673a20
Autor:
Lili Sun, Xiulan Deng, Dingnan Wang, Zhili Zheng, Xianggen Zhong, Shaohua Shi, Han Yu, Xinghua Shi, Zongying Xu, Dou Dou, Yunzhou Li
Publikováno v:
Experimental and Therapeutic Medicine
The therapeutic effects of melatonin on cholestatic liver injury have received widespread attention recently. The aim of the present study was to investigate the mechanisms of the anti-cholestatic effects of melatonin against α-naphthyl isothiocyana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06b93969c4ee5af38c3b32b5693b131d
http://europepmc.org/articles/PMC8343461
http://europepmc.org/articles/PMC8343461
Autor:
Guo Xiaohong, Wanfeng Zhang, Cao Guoqing, Gao Pengfei, Meng Li, Baoyu Le, Li Bugao, Pengkang Song, Cheng Zhimin, Zhang Ningfang
Publikováno v:
Asian-Australasian Journal of Animal Sciences, Vol 32, Iss 8, Pp 1084-1094 (2019)
Asian-Australasian Journal of Animal Sciences
Asian-Australasian Journal of Animal Sciences
OBJECTIVE The aim of this study was to select the candidate genes affecting meat quality and preliminarily explore the related molecular mechanisms in the Mashen pig. METHODS The present study explored genetic factors affecting meat quality in the Ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6852dc33505b7590f7ce1c0176486504
http://www.ajas.info/upload/pdf/ajas-18-0718.pdf
http://www.ajas.info/upload/pdf/ajas-18-0718.pdf
Publikováno v:
Environmental and Experimental Botany. 161:312-333
Stress leads to production of reactive oxygen species (ROS) and reactive nitrogen species (RNS). Among the RNS, nitric oxide (NO) is an important signaling molecule that mediates its effect majorly via a reversible post-translational modification (PT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cf0df2012e1cbbc492e121d929d3551
https://doi.org/10.1016/j.envexpbot.2018.10.010
https://doi.org/10.1016/j.envexpbot.2018.10.010
Autor:
Rebecca E. Saunders, Joana Cerveira, Sharon A. Tooze, Tamas Korcsmaros, Michael Howell, Axel Behrens, Ming Jiang, Tim Van Acker, Jaclyn S. Long, Harold B.J. Jefferies, Victoria M.-Y. Wang, Kevin M. Ryan, Jun-ichi Sakamaki, Padhmanand Sudhakar, Maria New
Publikováno v:
Cancer Research. 79:1884-1898
Pancreatic ductal adenocarcinoma (PDAC) is driven by metabolic changes in pancreatic cells caused by oncogenic mutations and dysregulation of p53. PDAC cell lines and PDAC-derived xenografts grow as a result of altered metabolic pathways, changes in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b051263b2cee80987e62d37b8198a670
https://doi.org/10.1158/0008-5472.can-18-2553
https://doi.org/10.1158/0008-5472.can-18-2553