Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Malancha, Karmakar"'
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background Antimicrobial resistance develops following the accrual of mutations in the bacterial genome, and may variably impact organism fitness and hence, transmission risk. Classical representation of tuberculosis (TB) dynamics using a si
Externí odkaz:
https://doaj.org/article/fa86f3f72dbd409bb035017eae0caf18
Autor:
Malancha Karmakar, Vittoria Cicaloni, Carlos H.M. Rodrigues, Ottavia Spiga, Annalisa Santucci, David B. Ascher
Publikováno v:
Current Research in Structural Biology, Vol 4, Iss , Pp 271-277 (2022)
Alkaptonuria (AKU), a rare genetic disorder, is characterized by the accumulation of homogentisic acid (HGA) in the body. Affected individuals lack functional levels of an enzyme required to breakdown HGA. Mutations in the homogentisate 1,2-dioxygena
Externí odkaz:
https://doaj.org/article/09d4b2fbbc3e4c9c8c87bcee86a8dfe2
Autor:
Vittoria Cicaloni, Malancha Karmakar, Luisa Frusciante, Francesco Pettini, Anna Visibelli, Maurizio Orlandini, Federico Galvagni, Maurizio Mongiat, Michael Silk, Federica Nardi, David Ascher, Annalisa Santucci, Ottavia Spiga
Publikováno v:
Frontiers in Bioinformatics, Vol 2 (2022)
The transmembrane glycoprotein CD93 has been identified as a potential new target to inhibit tumor angiogenesis. Recently, Multimerin-2 (MMRN2), a pan-endothelial extracellular matrix protein, has been identified as a ligand for CD93, but the interac
Externí odkaz:
https://doaj.org/article/06e83d3eadc84805a034ceb8e0e899cd
Autor:
Debebe Shaweno, Malancha Karmakar, Kefyalew Addis Alene, Romain Ragonnet, Archie CA Clements, James M. Trauer, Justin T. Denholm, Emma S. McBryde
Publikováno v:
BMC Medicine, Vol 16, Iss 1, Pp 1-18 (2018)
Abstract Background Tuberculosis (TB) transmission often occurs within a household or community, leading to heterogeneous spatial patterns. However, apparent spatial clustering of TB could reflect ongoing transmission or co-location of risk factors a
Externí odkaz:
https://doaj.org/article/bb23a46be53f4f20bd592fbc032015a9
Autor:
Malancha Karmakar, Carlos H M Rodrigues, Kathryn E Holt, Sarah J Dunstan, Justin Denholm, David B Ascher
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0217169 (2019)
Clinical resistance against Bedaquiline, the first new anti-tuberculosis compound with a novel mechanism of action in over 40 years, has already been detected in Mycobacterium tuberculosis. As a new drug, however, there is currently insufficient clin
Externí odkaz:
https://doaj.org/article/f760139f04a74740bd4baa6c42129654
Autor:
Annalisa Santucci, Ottavia Spiga, David B. Ascher, Vittoria Cicaloni, Carlos H M Rodrigues, Malancha Karmakar
Publikováno v:
Current Research in Structural Biology. 4:271-277
Alkaptonuria (AKU), a rare genetic disorder, is characterized by the accumulation of homogentisic acid (HGA) in the body. Affected individuals lack enough functional levels of an enzyme required to breakdown HGA. Mutations in the HGD gene cause AKU a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98ef9d83331533d2001485885dd70fb1
https://doi.org/10.1016/j.crstbi.2022.08.001
https://doi.org/10.1016/j.crstbi.2022.08.001
Publikováno v:
Journal of Infection. 79:572-581
Summary Objectives The globally distributed “Beijing” lineage of Mycobacterium tuberculosis has been associated with outbreaks worldwide. Laboratory based studies have suggested that Beijing lineage may have increased fitness; however, it has not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17411f7c9abf1ec9ee781f7a2e99f200
https://doi.org/10.1016/j.jinf.2019.09.016
https://doi.org/10.1016/j.jinf.2019.09.016
BackgroundAntimicrobial resistance develops following the accrual of mutations in the bacterial genome, and may variably impact organism fitness and hence, transmission risk. Classical representation of tuberculosis (TB) dynamics using a single or tw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e4bf3a9880ded3c94685f1aebda70bf
https://doi.org/10.1101/2021.01.12.426461
https://doi.org/10.1101/2021.01.12.426461
Autor:
Michael Silk, Malancha Karmakar, Douglas E. V. Pires, Joicymara S Xavier, Pâmela M Rezende, Edward Airey, Hardik H Parate, Carlos H M Rodrigues, Raghad Al-Jarf, Yoochan Myung, Juliana Assis Geraldo, João P L Velloso, Anjali Garg, Lucy Barr, David B. Ascher, Stephanie Portelli
Publikováno v:
Methods in Molecular Biology ISBN: 9781071608258
Artificial Neural Networks, 3rd Edition
Artificial Neural Networks, 3rd Edition
Mutations in protein-coding regions can lead to large biological changes and are associated with genetic conditions, including cancers and Mendelian diseases, as well as drug resistance. Although whole genome and exome sequencing help to elucidate po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33e74ad996187af5ee59e0377b193722
https://doi.org/10.1007/978-1-0716-0826-5_1
https://doi.org/10.1007/978-1-0716-0826-5_1
Autor:
Edward, Airey, Stephanie, Portelli, Joicymara S, Xavier, Yoo Chan, Myung, Michael, Silk, Malancha, Karmakar, João P L, Velloso, Carlos H M, Rodrigues, Hardik H, Parate, Anjali, Garg, Raghad, Al-Jarf, Lucy, Barr, Juliana A, Geraldo, Pâmela M, Rezende, Douglas E V, Pires, David B, Ascher
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2190
Mutations in protein-coding regions can lead to large biological changes and are associated with genetic conditions, including cancers and Mendelian diseases, as well as drug resistance. Although whole genome and exome sequencing help to elucidate po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e2dc2f3e852ddbd0602e223284c53a18
https://pubmed.ncbi.nlm.nih.gov/32804359
https://pubmed.ncbi.nlm.nih.gov/32804359