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Asymptomatic HIV-infected Individuals on Antiretroviral Therapy Exhibit Impaired Lung CD4+ T-Cell Responses to Mycobacteria

Autor: Jambo, Kondwani C., Banda, Dominic H., Afran, Louise, Kankwatira, Anstead M., Malamba, Rose D., Allain, Theresa J., Gordon, Stephen B., Heyderman, Robert S., David Russell, Mwandumba, Henry C.

Publikováno v: ResearcherID

HIV-infected persons on antiretroviral therapy (ART) remain at higher risk of pulmonary tuberculosis (TB) than HIV-uninfected individuals. This increased susceptibility may be caused by impairment of alveolar macrophage (AM) function and/or mycobacte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c038cf845d4f7279909e8fb662b2dbd6
https://europepmc.org/articles/PMC4299580/

Asymptomatic HIV-infected Individuals on Antiretroviral Therapy Exhibit Impaired Lung CD4⁺ T-Cell Responses to Mycobacteria.

Autor: Jambo, Kondwani C., Banda, Dominic H., Afran, Louise, Kankwatira, Anstead M., Malamba, Rose D., Allain, Theresa J., Gordon, Stephen B., Heyderman, Robert S., Russell, David G., Mwandumba, Henry C.

Publikováno v: American Journal of Respiratory & Critical Care Medicine; 10/15/2014, Vol. 190 Issue 8, p938-947, 14p, 1 Chart, 7 Graphs

HIV-associated disruption of lung cytokine networks is incompletely restored in asymptomatic HIV-infected Malawian adults on antiretroviral therapy.

Autor: Jambo KC; Malawi-Liverpool-Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi.; Dept of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.; These authors contributed equally., Tembo DL; Dept of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.; These authors contributed equally., Kamng'ona AW; Malawi-Liverpool-Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi.; Dept of Biomedical Sciences, University of Malawi, College of Medicine, Blantyre, Malawi., Musicha P; Malawi-Liverpool-Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi.; Dept of Pathology, University of Malawi, College of Medicine, Blantyre, Malawi., Banda DH; Malawi-Liverpool-Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi., Kankwatira AM; Malawi-Liverpool-Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi., Malamba RD; Malawi-Liverpool-Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi., Allain TJ; Dept of Medicine, University of Malawi, College of Medicine, Blantyre, Malawi., Heyderman RS; Malawi-Liverpool-Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi.; Division of Infection and Immunity, University College London, London, UK., Russell DG; Dept of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA., Mwandumba HC; Malawi-Liverpool-Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi.; Dept of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.; Dept of Medicine, University of Malawi, College of Medicine, Blantyre, Malawi.

Publikováno v: ERJ open research [ERJ Open Res] 2017 Dec 14; Vol. 3 (4). Date of Electronic Publication: 2017 Dec 14 (Print Publication: 2017).