Zobrazeno 1 - 10
of 362
pro vyhledávání: '"Malalties neurodegeneratives"'
Autor:
Jordi Soriano Fradera
Publikováno v:
Biophysica; Volume 3; Issue 1; Pages: 181-202
Neuronal cultures are one of the most important experimental models in modern interdisciplinary neuroscience, allowing to investigate in a control environment the emergence of complex behavior from an ensemble of interconnected neurons. Here, I revie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::959a8907ca0cbcdfbdc9f450044bfd6f
https://doi.org/10.3390/biophysica3010012
https://doi.org/10.3390/biophysica3010012
Autor:
Lillo Márquez, Alejandro
[cat] Els receptors acoblats a proteïna G o GPCR conformen la major superfamília de proteïnes de membrana cel·lular en organismes eucariotes. De fet, en humans s'han descrit més de 800 tipus de GPCR diferents que suposen al voltant d'un 5% del t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______963::904097650f61fc755fd4fc87380c068f
http://hdl.handle.net/10803/688470
http://hdl.handle.net/10803/688470
The amyloid state is commonly associated with various neurodegenerative diseases, but there are also functional amyloids involved in biological processes. Amyloid fibers possess properties such as mechanical strength and self-assembly, which are of i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1404::56d8454f6386034af29d2b3bc7df0f0d
https://ddd.uab.cat/record/279461
https://ddd.uab.cat/record/279461
Chronic low-dose exposure to organophosphorus (OP) toxicants is correlated with an increase in the risk of impaired cognition and neurodegenerative diseases. A mechanism to explain this relationship is needed. We suggest that the formation of organop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f36bf00203482cc338ad3d32ffe8326a
http://hdl.handle.net/2445/193966
http://hdl.handle.net/2445/193966
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 24; Pages: 15940
Heterozygous hTau mice were used for the study of tau seeding. These mice express the six human tau isoforms, with a high predominance of 3Rtau over 4Rtau. The following groups were assessed: (i) non-inoculated mice aged 9 months (n = 4); (ii) Alzhei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de3e5070c43260983ee09587f9f2d2c4
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Universidad de Barcelona
Tauopathies are a group of neurodegenerative diseases characterized by the hyperphosphorylation and deposition of tau proteins in the brain. In Alzheimer’s disease, and other related tauopathies, the pattern of tau deposition follows a stereotypica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fc0957b1c7664dcae576240e9f7e39f
http://hdl.handle.net/2445/190159
http://hdl.handle.net/2445/190159
Protein tyrosine phosphatase 1B (PTP1B) as a potential therapeutic target for neurological disorders
Autor:
Jordi Olloquequi, Amanda Cano, Elena Sanchez-López, Marina Carrasco, Ester Verdaguer, Ana Fortuna, Jaume Folch, Mònica Bulló, Carme Auladell, Antoni Camins, Miren Ettcheto
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Protein tyrosine phosphatase 1B (PTP1B) is a typical member of the PTP family, considered a direct negative regulator of several receptor and receptor-associated tyrosine kinases. This widely localized enzyme has been involved in the pathophysiology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82c3b4f1ece3d4d6c2524de633ac5c14
http://hdl.handle.net/10261/280889
http://hdl.handle.net/10261/280889
Autor:
José Luis Molinuevo, Carolina Minguillon, José Maria González-de-Echávarri, Marta Milà-Alomà, Marc Suárez-Calvet, Maryline Simon, Eider M. Arenaza-Urquijo, Marta Crous-Bou, Henrik Zetterberg, Grégory Operto, Gonzalo Sánchez-Benavides, Juan Domingo Gispert, Oriol Grau-Rivera, Alfa Study, Aleix Sala-Vila, Karine Fauria, Kaj Blennow, Natalia Vilor-Tejedor, Gwendlyn Kollmorgen
Publikováno v:
Neurobiology of Aging, 104, 24-31. Elsevier Inc.
Dipòsit Digital de la UB
Universidad de Barcelona
Dipòsit Digital de la UB
Universidad de Barcelona
Neurofilament light chain (NfL) is an axonal protein that when measured in cerebrospinal fluid (CSF) serves as a biomarker of neurodegeneration. We aimed at investigating the association among CSF NfL, presence of Subjective Cognitive Decline (SCD) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::041e058734b05a73ba861bfe0f987131
http://www.scopus.com/inward/record.url?scp=85109354586&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85109354586&partnerID=8YFLogxK
Autor:
Foteini Vasilopoulou, Aina Bellver-Sanchis, Júlia Companys-Alemany, Júlia Jarne-Ferrer, Alba Irisarri, Verónica Palomera-Ávalos, Celia Gonzalez-Castillo, Daniel Ortuño-Sahagún, Coral Sanfeliu, Mercè Pallàs, Christian Griñán-Ferré
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Cells; Volume 11; Issue 16; Pages: 2603
Universidad de Barcelona
Cells; Volume 11; Issue 16; Pages: 2603
Behavioural and psychological symptoms of dementia (BPSD) are presented in 95% of Alzheimer’s Disease (AD) patients and are also associated with neurotrophin deficits. The molecular mechanisms leading to age-related diseases are still unclear; howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::016a4782230ae8ebaa5c103f72435f10
http://hdl.handle.net/2445/189685
http://hdl.handle.net/2445/189685
Autor:
Júlia Jarne-Ferrer, Christian Griñán-Ferré, Aina Bellver-Sanchis, Santiago Vázquez, Diego Muñoz-Torrero, Mercè Pallàs
Publikováno v:
Pharmaceuticals; Volume 15; Issue 8; Pages: 908
Dipòsit Digital de la UB
Universidad de Barcelona
Dipòsit Digital de la UB
Universidad de Barcelona
Alzheimer’s disease (AD) is a progressive neurological disorder with multifactorial and heterogeneous causes. AD involves several etiopathogenic mechanisms such as aberrant protein accumulation, neurotransmitter deficits, synaptic dysfunction and n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2676c47ad0276b8811b42e7e3edbb2e7