Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Malak Alannan"'
Publikováno v:
Cells, Vol 11, Iss 24, p 4132 (2022)
Metabolic rewiring and defective immune responses are considered to be the main driving forces sustaining cell growth and oncogenesis in many cancers. The atypical enzyme, proprotein convertase subtilisin/kexin type 9 (PCSK9), is produced by the live
Externí odkaz:
https://doaj.org/article/9c5976d44e174a8e867906085340e64d
Autor:
Malak Alannan, Hala Fatrouni, Véronique Trézéguet, Franziska Dittrich-Domergue, Patrick Moreau, Géraldine Siegfried, Benjamin Liet, Abdel-Majid Khatib, Christophe F. Grosset, Bassam Badran, Hussein Fayyad-Kazan, Aksam J. Merched
Publikováno v:
Cells, Vol 12, Iss 1, p 62 (2022)
Deregulated lipid metabolism is a common feature of liver cancers needed to sustain tumor cell growth and survival. We aim at taking advantage of this vulnerability and rewiring the oncogenic metabolic hub by targeting the key metabolic player pro-pr
Externí odkaz:
https://doaj.org/article/4663be7435534a34a53819485f818f91
Autor:
Malak Alannan, Véronique Trézéguet, Nivea Dias Amoêdo, Rodrigue Rossignol, Walid Mahfouf, Hamid Reza Rezvani, Franziska Dittrich-Domergue, Patrick Moreau, Sabrina Lacomme, Etienne Gontier, Christophe F. Grosset, Bassam Badran, Hussein Fayyad-Kazan, Aksam J. Merched
Publikováno v:
Cancers, Vol 15, Iss 1, p 3 (2022)
Alterations in lipid handling are an important hallmark in cancer. Our aim here is to target key metabolic enzymes to reshape the oncogenic lipid metabolism triggering irreversible cell breakdown. We targeted the key metabolic player proprotein conve
Externí odkaz:
https://doaj.org/article/c8f46b1e53a741589da3b2de512778b4
Publikováno v:
Biochemistry
Biochemistry, American Chemical Society, 2020, 59 (41), pp.3951-3964. ⟨10.1021/acs.biochem.0c00477⟩
Biochemistry, 2020, 59 (41), pp.3951-3964. ⟨10.1021/acs.biochem.0c00477⟩
Biochemistry, American Chemical Society, 2020, 59 (41), pp.3951-3964. ⟨10.1021/acs.biochem.0c00477⟩
Biochemistry, 2020, 59 (41), pp.3951-3964. ⟨10.1021/acs.biochem.0c00477⟩
International audience; Cancer cells are highly dependent on different metabolic pathways for sustaining their survival, growth, and proliferation. Lipid metabolism not only provides the energetic needs of the cells but also provides the raw material
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::529e77c58f4481749fb0c3d96e128e16
https://hal.archives-ouvertes.fr/hal-03373099/document
https://hal.archives-ouvertes.fr/hal-03373099/document
Autor:
Bassam Badran, Redouane Rouas, Philippe Martiat, Arsène Burny, Luc Vanhamme, Rim ElDirani, Eva Hamade, Mehdi Najar, Makram Merimi, Malak Alannan, Aksam Merched, Walid Rachidi, Philippe Lewalle, Mohammad Fayyad-Kazan, Nizar Bitar, Hussein Fayyad-Kazan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7eb7425dbd3b27a0994b421e6459f12e
https://doi.org/10.37247/imcac.1.2020.1
https://doi.org/10.37247/imcac.1.2020.1