Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Mala Mani"'
Autor:
Daniel R. Carrasco, Kenneth C. Anderson, Sanford D. Markowitz, Lois L. Myeroff, Monica Bertagnolli, Victor Pena-Cruz, Felipe Diaz-Griffero, Hiroshi Ikeda, Jui Dutta-Simmons, Moshe E. Gatt, Kohichi Takada, Yunyu Zhang, Daniel E. Carrasco, Mala Mani
Several components of the Wnt signaling cascade have been shown to function either as tumor suppressor proteins or as oncogenes in multiple human cancers, underscoring the relevance of this pathway in oncogenesis and the need for further investigatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c01ae47eed5506ca5d04031922634e2
https://doi.org/10.1158/0008-5472.c.6499085.v1
https://doi.org/10.1158/0008-5472.c.6499085.v1
Autor:
Daniel R. Carrasco, Kenneth C. Anderson, Sanford D. Markowitz, Lois L. Myeroff, Monica Bertagnolli, Victor Pena-Cruz, Felipe Diaz-Griffero, Hiroshi Ikeda, Jui Dutta-Simmons, Moshe E. Gatt, Kohichi Takada, Yunyu Zhang, Daniel E. Carrasco, Mala Mani
Supplementary Figures 1-8, Methods from BCL9 Promotes Tumor Progression by Conferring Enhanced Proliferative, Metastatic, and Angiogenic Properties to Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05acb617d1847dd9662fc510f590770e
https://doi.org/10.1158/0008-5472.22379003.v1
https://doi.org/10.1158/0008-5472.22379003.v1
Autor:
Alexei Protopopov, Moshe E. Gatt, Daniel E. Carrasco, Bart Barlogie, Daniel R. Carrasco, John D. Shaughnessy, Teru Hideshima, Olle Sangfelt, Elena Ivanova, Kohichi Takada, Mala Mani, Dan Grandér, Kenneth C. Anderson, Mikael Lerner, Marjorie Pick
Publikováno v:
British Journal of Haematology. 162:210-220
Multiple myeloma (MM) is an incurable neoplasm caused by proliferation of malignant plasma cells in the bone marrow (BM). MM is characterized frequently by a complete or partial deletion of chromosome 13q14, seen in more than 50% of patients at diagn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cbd60d2874ba1d2f3d57022ff1f35e1
https://doi.org/10.1111/bjh.12365
https://doi.org/10.1111/bjh.12365
Autor:
Karthikeyan Kandavelou, Vitali Alexeev, Joy Wu, Curt I. Civin, Srinivasan Chandrasegaran, Mala Mani, Sivaprakash Ramalingam, Viktoriya London
Publikováno v:
Biochemical and Biophysical Research Communications. 388:56-61
Targeted introduction of a double-stranded break (DSB) using designer zinc finger nucleases (ZFNs) in mammalian cells greatly enhances gene targeting - homologous recombination (HR) at a chosen endogenous target gene, which otherwise is limited by lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45010f93b6649f82fc91b5aca85f0722
https://doi.org/10.1016/j.bbrc.2009.07.112
https://doi.org/10.1016/j.bbrc.2009.07.112
Autor:
Monica M. Bertagnolli, Daniel E. Carrasco, Yunyu Zhang, Sanford D. Markowitz, Lois Myeroff, Moshe E. Gatt, Mala Mani, Daniel R. Carrasco, Hiroshi Ikeda, Kohichi Takada, Jui Dutta-Simmons, Kenneth C. Anderson, Felipe Diaz-Griffero, Victor Pena-Cruz
Publikováno v:
Cancer Research. 69:7577-7586
Several components of the Wnt signaling cascade have been shown to function either as tumor suppressor proteins or as oncogenes in multiple human cancers, underscoring the relevance of this pathway in oncogenesis and the need for further investigatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a494c9896a951f6c24fd9ac139e1f444
https://doi.org/10.1158/0008-5472.can-09-0773
https://doi.org/10.1158/0008-5472.can-09-0773
Autor:
Daniel R. Carrasco, Yunyu Zhang, Moshe E. Gatt, Kohichi Takada, Gullu Gorgun, Anthony Letai, Teru Hideshima, Jui Dutta-Simmons, Kenneth C. Anderson, Mala Mani, Noopur Raje, Daniel E. Carrasco, Nicole Carlson, Yu-Tzu Tai
Publikováno v:
Blood. 114:2699-2708
Multiple myeloma (MM) is a cancer of plasma cells with complex molecular characteristics that evolves from monoclonal gammopathy of undetermined significance, a highly prevalent premalignant condition. MM is the second most frequent hematologic cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ac0d2df529362e83f1b5acd92843954
https://doi.org/10.1182/blood-2008-12-194290
https://doi.org/10.1182/blood-2008-12-194290
Autor:
Kumar Sukhdeo, Yunyu Zhang, Mei Zheng, Melissa Rooney, Haiying He, Daniel R. Carrasco, Jui Dutta, Daniel E. Carrasco, Constantine S. Mitsiades, Kenneth C. Anderson, Mala Mani, Hiroshi Yasui, Yu-Tzu Tai
Publikováno v:
Proceedings of the National Academy of Sciences. 104:7516-7521
Multiple myeloma (MM) is an invariably fatal form of cancer characterized by clonal proliferation of malignant plasma cells in the bone marrow. The canonical Wnt signaling pathway is activated in MM cells through constitutively active β-catenin, a m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a7b5ddb1a0ff5591cc0797daa86f54
https://doi.org/10.1073/pnas.0610299104
https://doi.org/10.1073/pnas.0610299104
Autor:
Jeremy M Berg, Srinivasan Chandrasegaran, Mala Mani, Jeffrey S. Smith, Karthikeyan Kandavelou
Publikováno v:
Biochemical and Biophysical Research Communications. 334:1191-1197
Custom-designed zinc finger nucleases (ZFNs) are becoming powerful tools in gene targeting-the process of replacing a gene within a genome by homologous recombination. Here, we have studied the DNA cleavage by one such ZFN, DeltaQNK-FN, in order to g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::641527a8b26550f68efee7e61b8e8cdd
https://doi.org/10.1016/j.bbrc.2005.07.021
https://doi.org/10.1016/j.bbrc.2005.07.021
Autor:
Ramesh A. Shivdasani, Di Zhu, Nikhil C. Munshi, Andrew L. Kung, Daniel R. Carrasco, Madeleine E. Lemieux, Jeremy Ryan, Daniel E. Carrasco, Gregory H. Bird, Kohichi Takada, David Horst, Wenqing Xu, Mala Mani, Loren D. Walensky, Jianjun Zhao, Kumar Sukhdeo, Mariateresa Fulciniti
Publikováno v:
Science translational medicine. 4(148)
Deregulated Wnt/β-catenin signaling underlies the pathogenesis of a broad range of human cancers, yet the development of targeted therapies to disrupt the resulting aberrant transcription has proved difficult because the pathway comprises large prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80c021febb9c22d9f29d16cf7d007401
https://pubmed.ncbi.nlm.nih.gov/22914623
https://pubmed.ncbi.nlm.nih.gov/22914623
Autor:
Daniel R. Carrasco, Ito S, KC Anderson, Pena-Cruz, Mendez G, Kumar Sukhdeo, Mala Mani, Kohichi Takada, Teru Hideshima
Publikováno v:
Leukemia. 26(5)
β-catenin is dynamically stored and cleared in multiple myeloma by the proteasome–aggresome–autophagosome–lysosome pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc47187d22e3f38f4227df0acf94e2be
https://pubmed.ncbi.nlm.nih.gov/22051532
https://pubmed.ncbi.nlm.nih.gov/22051532