Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Mala Mahendroo"'
Publikováno v:
STAR Protocols, Vol 4, Iss 4, Pp 102631- (2023)
Summary: A challenge in studying cervical epithelial cell biology at the single-cell level is that differentiated subtypes, in particular mucus-secreting goblet cells, are sensitive to disassociating enzymes making isolation of all epithelial subpopu
Externí odkaz:
https://doaj.org/article/e85d0dae22324ab99fb9e573c1d2f796
Autor:
Anne Cooley, ShanmugaPriyaa Madhukaran, Elizabeth Stroebele, Mariano Colon Caraballo, Lei Wang, Yucel Akgul, Gary C. Hon, Mala Mahendroo
Publikováno v:
iScience, Vol 26, Iss 2, Pp 105953- (2023)
Summary: The cervical epithelium undergoes changes in proliferation, differentiation, and function that are critical to ensure fertility and maintain pregnancy. Here, we identify cervical epithelial subtypes in non-pregnant, pregnant, and in labor mi
Externí odkaz:
https://doaj.org/article/609d96e72e6e46dd9c0bbf17838065f9
Autor:
Hee Ryung Lee, Ilyas Saytashev, Vinh Nguyen Du Le, Mala Mahendroo, Jessica Ramella-Roman, Tatiana Novikova
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Preterm birth risk is associated with early softening of the uterine cervix in pregnancy due to the accelerated remodeling of collagen extracellular matrix. Studies of mice model of pregnancy were performed with an imaging Mueller polarimete
Externí odkaz:
https://doaj.org/article/142d02fb78754b32994e37742b383e63
Autor:
Kyoko Yoshida, Hongfeng Jiang, MiJung Kim, Joy Vink, Serge Cremers, David Paik, Ronald Wapner, Mala Mahendroo, Kristin Myers
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112391 (2014)
The changes in the mechanical integrity of the cervix during pregnancy have implications for a successful delivery. Cervical collagens are known to remodel extensively in mice with progressing gestation leading to a soft cervix at term. During this p
Externí odkaz:
https://doaj.org/article/c722cf13d143474bb777367aaafbc01f
Autor:
Helene C D Østerholt, Ingrid Dannevig, Myra H Wyckoff, Jie Liao, Yucel Akgul, Mrithyunjay Ramgopal, Dan S Mija, Naeun Cheong, Christopher Longoria, Mala Mahendroo, Britt Nakstad, Ola D Saugstad, Rashmin C Savani
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38839 (2012)
BACKGROUND: Newborn resuscitation with 100% oxygen is associated with oxidative-nitrative stresses and inflammation. The mechanisms are unclear. Hyaluronan (HA) is fragmented to low molecular weight (LMW) by oxidative-nitrative stresses and can promo
Externí odkaz:
https://doaj.org/article/5bd74f24ffbc401588cc5cc0207dfe5e
Autor:
Shanmugasundaram Nallasamy, Kristin M. Myers, Mala Mahendroo, S.P. Madhukaran, Charles Jayyosi, Nicole Lee
Publikováno v:
Acta Biomaterialia. 135:414-424
The cervical remodeling process during pregnancy is characterized by progressive compositional and structural changes in the tissues extra-cellular matrix (ECM). Appropriately timed remodeling is critical for healthy gestation and prevention of prema
Autor:
Hector Palacios, Rohit Setlem, Marc K. Hellerstein, Shanmugasundaram Nallasamy, Kelvin W. Li, Mala Mahendroo, Mahalakshmi Shankaran, Edward Cao, Mariano Colon Caraballo
Publikováno v:
Biol Reprod
During gestation, the female reproductive tract must maintain pregnancy while concurrently preparing for parturition. Here, we explore the transitions in gene expression and protein turnover (fractional synthesis rates [FSR]) by which the cervix impl
Autor:
Anne Cooley, ShanmugaPriyaa Madhukaran, Elizabeth Stroebele, Mariano Colon Caraballo, Lei Wang, Gary C. Hon, Mala Mahendroo
The cervical epithelium undergoes continuous changes in proliferation, differentiation, and function that are critical before pregnancy to ensure fertility and during pregnancy to provide a physical and immunoprotective barrier for pregnancy maintena
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37117ec1c68b991b4cc249b7e9141bff
https://doi.org/10.1101/2022.07.26.501609
https://doi.org/10.1101/2022.07.26.501609
Publikováno v:
Annals of Biomedical Engineering. 49:1874-1887
Throughout the estrus cycle, the extracellular matrix (ECM) and cervical smooth muscle cells (cSMC) coordinate to accomplish normal physiologic function in the non-pregnant cervix. While previous uniaxial experiments provide fundamental knowledge abo
Autor:
Hee Ryung Lee, Ilyas Saytashev, Vinh Nguyen Du Le, Mala Mahendroo, Jessica C. Ramella-Roman, Tatiana Novikova
Publikováno v:
Polarized Light and Optical Angular Momentum for Biomedical Diagnostics 2022.