Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Mala L, Radhakrishnan"'
Publikováno v:
ACS Omega, Vol 8, Iss 37, Pp 33701-33711 (2023)
Externí odkaz:
https://doaj.org/article/ddf8d194889f45aab453ae0ee64d559f
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract We formulate a mathematical model of a rolling “molecular wheelbarrow”—a two-wheeled nanoscale molecular machine—informed by experiments on molecular machines recently synthesized in labs. The model is a nonholonomic system (briefly,
Externí odkaz:
https://doaj.org/article/dd01ba56c1cd423290416af8f705adf4
Autor:
Donald E. Elmore, Mala L. Radhakrishnan, Mona L. Hall, Adam G. W. Matthews, Melissa A. Beers, John W. Goss, Elizabeth S. C. Oakes
Publikováno v:
Biochemistry and Molecular Biology Education. 49:859-869
We describe a first-semester, integrated, introductory biology and chemistry course for undergraduates at Wellesley College in Wellesley, MA, USA. Our vision was to create a supportive learning community in which students could comfortably make conne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50e1b5c580295464342f4f51b08120ee
https://doi.org/10.1002/bmb.21565
https://doi.org/10.1002/bmb.21565
Autor:
Elizabeth S. C. Oakes, Donald E. Elmore, Akila Weerapana, Pamela L. Taylor, Sarah Pociask, Adam G. W. Matthews, Mala L. Radhakrishnan
Publikováno v:
Biochemistry and Molecular Biology Education. 49:737-747
In the Fall of 2016, we created an integrated introductory biology/chemistry course for first-semester students at Wellesley College. This course was designed to meaningfully integrate chemistry and molecular cell biology while also building communit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b36f6dba39bd40fc8810cf2bd9da82b9
https://doi.org/10.1002/bmb.21555
https://doi.org/10.1002/bmb.21555
Publikováno v:
The Journal of Physical Chemistry B. 123:10718-10734
The cell is a crowded place, and it may be crucial at times to account for the local environment when studying determinants of molecular recognition. In this work, we use continuum electrostatics calculations on snapshots extracted from molecular dyn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51f609ddbf2de5cba1779c655257cb69
https://doi.org/10.1021/acs.jpcb.9b09478
https://doi.org/10.1021/acs.jpcb.9b09478
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98618 (2014)
Macromolecular crowding within the cell can impact both protein folding and binding. Earlier models of cellular crowding focused on the excluded volume, entropic effect of crowding agents, which generally favors compact protein states. Recently, othe
Externí odkaz:
https://doaj.org/article/14109fb2cd384b44a1a5cf8f64e82ea1
Autor:
Patrick Flaherty, Mala L Radhakrishnan, Tuan Dinh, Robert A Rebres, Tamara I Roach, Michael I Jordan, Adam P Arkin
Publikováno v:
PLoS Computational Biology, Vol 4, Iss 9, p e1000185 (2008)
Macrophage cells that are stimulated by two different ligands that bind to G-protein-coupled receptors (GPCRs) usually respond as if the stimulus effects are additive, but for a minority of ligand combinations the response is synergistic. The G-prote
Externí odkaz:
https://doaj.org/article/67020bd7c4b647a4a7b7ede15a237b85
Autor:
Mala L. Radhakrishnan, Rachel Kim
Publikováno v:
The Journal of Chemical Physics. 154:225101
The crowded cellular environment can affect biomolecular binding energetics, with specific effects depending on the properties of the binding partners and the local environment. Often, crowding effects on binding are studied on particular complexes,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e164f7f104bdb64e9badbaa871a90bc6
https://doi.org/10.1063/5.0042082
https://doi.org/10.1063/5.0042082
Autor:
Mala L. Radhakrishnan, Oscar Fernandez
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
We formulate a mathematical model of a rolling “molecular wheelbarrow”—a two-wheeled nanoscale molecular machine—informed by experiments on molecular machines recently synthesized in labs. The model is a nonholonomic system (briefly, a system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c6a519b2096824f7a27b3fbe7edd483
http://europepmc.org/articles/PMC6173740
http://europepmc.org/articles/PMC6173740
Autor:
Alyssa J. Kranc, Mala L. Radhakrishnan
Publikováno v:
Biophysical Journal. 116:561a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c1720645610af99a6574975e7290b1b
https://doi.org/10.1016/j.bpj.2018.11.3017
https://doi.org/10.1016/j.bpj.2018.11.3017