Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Maksymilian Marek Zegota"'
Autor:
Astrid Johanna Heck, Tao Wang, Lutz Nuhn, Tanja Weil, Seah Ling Kuan, Dominik Schauenburg, Marco Raabe, David Y. W. Ng, Siska Führer, Michaela Pieszka, Maksymilian Marek Zegota
Publikováno v:
Macromolecular Bioscience
With the advent of chemical strategies that allow the design of smart bioconjugates, peptide- and protein-drug conjugates are emerging as highly efficient therapeutics to overcome limitations of conventional treatment, as exemplified by antibody-drug
Autor:
Marco Raabe, David Y. W. Ng, Seah Ling Kuan, Maksymilian Marek Zegota, Astrid Johanna Heck, Michaela Pieszka, Lutz Nuhn, Tao Wang, Tanja Weil
With the advent of chemical strategies that allow the design of smart bioconjugates, peptide- and protein-drug conjugates are emerging as highly efficient therapeutics to overcome limitations of conventional treatment, as exemplified by antibody-drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21883adf2fae1b1331e36f1197c4f8ee
https://doi.org/10.33774/chemrxiv-2021-5hvgc
https://doi.org/10.33774/chemrxiv-2021-5hvgc
Autor:
Pierpaolo Moscariello, Bellinda Lantzberg, Jaime A. S. Coelho, David Y. W. Ng, Seah Ling Kuan, Manfred Wagner, Michael Müller, Pedro M. P. Gois, Maksymilian Marek Zegota, Tanja Weil, María Martínez-Negro, Gönül Kizilsavas, Svenja Morsbach
Publikováno v:
Journal of the American Chemical Society
Dynamic covalent chemistry (DCvC) has emerged as a versatile synthetic tool for devising stable, stimuli-responsive linkers or conjugates. The interplay of binding affinity, association and dissociation constants exhibits a strong influence on the se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4172420a038d397f7884ccf329171c6f
https://doi.org/10.33774/chemrxiv-2021-8gznz
https://doi.org/10.33774/chemrxiv-2021-8gznz
Autor:
Seah Ling Kuan, Lujuan Xu, Tanja Weil, João C. F. Nogueira, Vijay Chudasama, Marco Raabe, Maksymilian Marek Zegota
Publikováno v:
Organic & Biomolecular Chemistry
An inverse electron demand Diels–Alder reaction between tetrazine and trans-cyclooctene (TCO) holds great promise for protein modification and manipulation. Herein, we report the design and synthesis of a tetrazine-based disulfide rebridging reagen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a5bcfb90b046dd0d006e0beb76df6ec
https://hdl.handle.net/21.11116/0000-0005-B073-221.11116/0000-0005-B075-0
https://hdl.handle.net/21.11116/0000-0005-B073-221.11116/0000-0005-B075-0
Autor:
Vijay P.S. Rawat, Stefanie Sieste, Anne Stumper, Naidu M. Vegi, Christian Buske, Tanja Weil, Michaela Feuring-Buske, Maksymilian Marek Zegota, Seah Ling Kuan, Sabyasachi Chakrabortty, Sven Rau
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Acute myeloid leukemia (AML) is characterized by relapse and treatment resistance in a major fraction of patients, underlining the need of innovative AML targeting therapies. Here we analysed the therapeutic potential of an innovative biohybrid consi
Autor:
Thorsten Lückerath, Tanja Weil, Maksymilian Marek Zegota, Pedro M. P. Gois, Jaime A. S. Coelho, Michaela Pieszka, Manfred Wagner, David Y. W. Ng, Andreas Riegger, Marco Hebel, Gönül Kizilsavas, Jasmina Gačanin
Publikováno v:
Journal of the American Chemical Society
The development of a synthetic code that enables a sequence programmable feature like DNA represents a key aspect toward intelligent molecular systems. We developed herein the well-known dynamic covalent interaction between boronic acids (BAs) and ca
Autor:
Andreas Riegger, Manfred Wagner, Maksymilian Marek Zegota, Jaime A. S. Coelho, Tanja Weil, David Y. W. Ng, Michaela Pieszka, Pedro M. P. Gois, Thorsten Lückerath, Jasmina Gačanin, Marco Hebel, Gönül Kizilsavas
Publikováno v:
Journal of the American Chemical Society
The development of a synthetic code that enables a sequence programmable feature like DNA represents a key aspect toward intelligent molecular systems. We developed herein the well-known dynamic covalent interaction between boronic acids (BAs) and ca
Autor:
Tao Wang, Tanja Weil, David Y. W. Ng, Christiane Seidler, Maksymilian Marek Zegota, Seah Ling Kuan
Publikováno v:
Bioconjugate Chemistry
The development of small protein tags that exhibit bioorthogonality, bond stability, and reversibility, as well as biocompatibility, holds great promise for applications in cellular environments enabling controlled drug delivery or for the constructi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96f6045e7501448b43f3c023a77dc264
https://hdl.handle.net/21.11116/0000-0002-0634-D21.11116/0000-0002-805F-3
https://hdl.handle.net/21.11116/0000-0002-0634-D21.11116/0000-0002-805F-3
Autor:
Tanja Weil, Marco Raabe, Christiane Seidler, Maksymilian Marek Zegota, David Y. W. Ng, Seah Ling Kuan
Publikováno v:
Chemistry – An Asian Journal
Chemistry, an Asian Journal
Chemistry-An Asian Journal
Chemistry, an Asian Journal
Chemistry-An Asian Journal
Dynamic covalent chemistry is a versatile and powerful tool that integrates both stable chemical bonds and stimulus responsiveness into the construction of smart biotherapeutics. With minimalistic molecular design, a dynamic covalent protein assembly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab2d5c835561ac99ff64e85afc1b1e60
https://hdl.handle.net/21.11116/0000-0002-97A5-921.11116/0000-0005-4E80-3
https://hdl.handle.net/21.11116/0000-0002-97A5-921.11116/0000-0005-4E80-3