Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Maksym Bobrovskyy"'
Autor:
Anustup Poddar, Muhammad S. Azam, Tunc Kayikcioglu, Maksym Bobrovskyy, Jichuan Zhang, Xiangqian Ma, Piyush Labhsetwar, Jingyi Fei, Digvijay Singh, Zaida Luthey-Schulten, Carin K. Vanderpool, Taekjip Ha
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Bacterial small RNA SgrS binds and regulates its primary target, ptsG mRNA. Here the authors employ Sort-Seq and super resolution imaging to investigate in vivo target recognition and rejection kinetics of SgrS.
Externí odkaz:
https://doaj.org/article/260d7031d6064787a1c0ef3b7e025390
Publikováno v:
Infection and Immunity. 91
Staphylococcus aureus bears a type 7b secretion system (T7bSS) that assembles in the bacterial envelope to promote the secretion of WXG-like proteins and toxic effectors bearing LXG domains. Cognate immunity proteins bind cytosolic effectors to mute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c637cb01dfc668bc49ca7d65a4fc2e9e
https://doi.org/10.1128/iai.00015-23
https://doi.org/10.1128/iai.00015-23
Publikováno v:
The Journal of biological chemistry. 298(9)
Secretion systems utilize ATPase activity to facilitate the translocation of proteins into and across membranes. In bacteria, the universally conserved SecA ATPase binds a large repertoire of preproteins and interacts with the SecYEG translocon. In c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b30936b63c7e5e32c3d5df2db2aa676
https://pubmed.ncbi.nlm.nih.gov/35921891
https://pubmed.ncbi.nlm.nih.gov/35921891
Autor:
Digvijay Singh, Piyush Labhsetwar, Zaida Luthey-Schulten, Carin K. Vanderpool, Muhammad S. Azam, Jichuan Zhang, Tunc Kayikcioglu, Jingyi Fei, Maksym Bobrovskyy, Xiangqian Ma, Anustup Poddar, Taekjip Ha
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Base-pairing interactions mediate many intermolecular target recognition events. Even a single base-pair mismatch can cause a substantial difference in activity but how such changes influence the target search kinetics in vivo is unknown. Here, we us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36337f4907ce931dd0db7c683da52c1f
https://pubmed.ncbi.nlm.nih.gov/33558533
https://pubmed.ncbi.nlm.nih.gov/33558533
Autor:
Digvijay Singh, Xiangqian Ma, Maksym Bobrovskyy, Jichuan Zhang, Muhammad S. Azam, Piyush Labhsetwar, Jingyi Fei, Carin K. Vanderpool, Anustup Poddar, Taekjip Ha, Tunc Kayikcioglu, Zaida Luthey-Schulten
Base-pairing interactions mediate intermolecular target recognition in many biological systems and applications, including DNA repair, CRISPR, microRNA, small RNA (sRNA) and antisense oligo therapies. Even a single base-pair mismatch can cause a subs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28e80da556499362e1552079b0ae20ec
https://doi.org/10.1101/2020.07.24.215095
https://doi.org/10.1101/2020.07.24.215095
Autor:
Xiangqian Ma, Tina M. Henkin, Anustup Poddar, Maksym Bobrovskyy, Jichuan Zhang, Jane K. Frandsen, Carin K. Vanderpool, Taekjip Ha, Muhammad S. Azam
Publikováno v:
Mol Microbiol
Small RNA (sRNA) regulators promote efficient responses to stress, but the mechanisms for prioritizing target mRNA regulation remain poorly understood. This study examines mechanisms underlying hierarchical regulation by the sRNA SgrS, found in enter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cb26232a046482e5f95363e743498e5
https://pubmed.ncbi.nlm.nih.gov/31340077
https://pubmed.ncbi.nlm.nih.gov/31340077
Publikováno v:
Journal of Bacteriology. 200
The ESAT-6-like secretion system (ESS) of Staphylococcus aureus is assembled in the bacterial membrane from core components that promote the secretion of WXG-like proteins (EsxA, EsxB, EsxC, and EsxD) and the EssD effector. Genes encoding the ESS sec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c2b5d0e03d9059ce327252f4788adab
https://doi.org/10.1128/jb.00268-18
https://doi.org/10.1128/jb.00268-18
Autor:
Maksym Bobrovskyy, Carin K. Vanderpool
Publikováno v:
Molecular Microbiology. 99:254-273
The Escherichia coli small RNA SgrS controls a metabolic stress response that occurs upon accumulation of certain glycolytic intermediates. SgrS base pairs with and represses translation of ptsG and manXYZ mRNAs, which encode sugar transporters, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc2eadd94c88e55991c0074cc8438ddd
https://doi.org/10.1111/mmi.13230
https://doi.org/10.1111/mmi.13230
Autor:
Tina M. Henkin, Jane K. Frandsen, Maksym Bobrovskyy, Carin K. Vanderpool, Jichuan Zhang, Anustup Poddar, Taekjip Ha, Muhammad S. Azam
The mechanisms by which small RNA (sRNA) regulators select and prioritize target mRNAs remain poorly understood, but serve to promote efficient responses to environmental cues and stresses. We sought to uncover mechanisms that establish regulatory hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a5ede33ea37937c7255171f6b40784a