Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Maksym A. Dedushko"'
Publikováno v:
Inorg Chem
Superoxide (O(2)(•−)) is a toxic radical, generated via the adventitious reduction of dioxygen (O(2)), which has been implicated in a number of human disease states. Nonheme iron enzymes, superoxide reductase (SOR) and superoxide dismutase (SOD),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::287397507116b7144219b54003d58f9b
https://doi.org/10.1021/acs.inorgchem.1c00336
https://doi.org/10.1021/acs.inorgchem.1c00336
Publikováno v:
J Am Chem Soc
Herein, we examine the electronic and geometric structural properties of O(2)-derived aliphatic thiolate-ligated Feperoxo, Fe-hydroxo, and Fe(IV) oxo compounds. The latter cleaves strong C–H bonds (96 kcal mol(−1)) on par with the valine C–H bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31a35d9a3d5cbaa01b0aba09a4717d9b
https://pubmed.ncbi.nlm.nih.gov/35522532
https://pubmed.ncbi.nlm.nih.gov/35522532
Autor:
Julie A. Kovacs, Dirk Schweitzer, Rodney D. Swartz, Maksym A. Dedushko, Maike N. Blakely, Werner Kaminsky
Publikováno v:
J Biol Inorg Chem
In order to shed light on metal-dependent mechanisms for O-O bond cleavage, and its microscopic reverse, we compare herein the electronic and geometric structures of O(2)-derived binuclear Co(III)- and Mn(III)-peroxo compounds. Binuclear metal peroxo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::876961a91850bdc30e58f86d3224eb41
https://doi.org/10.1007/s00775-019-01686-x
https://doi.org/10.1007/s00775-019-01686-x
Autor:
Julie A. Kovacs, Maike N. Blakely, Gloria Villar-Acevedo, Penny Chaau Yan Poon, Maksym A. Dedushko
Publikováno v:
Journal of the American Chemical Society. 141:1867-1870
Herein, we describe an alkyl thiolate-ligated iron complex that reacts with dioxygen to form an unprecedented example of an iron superoxo (O2•–) intermediate, [FeIII(S2Me2N3(Pr,Pr))(O2)] (4), which...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e323a9fec8f59f162c9c2e8ca8f55e38
https://doi.org/10.1021/jacs.8b12670
https://doi.org/10.1021/jacs.8b12670
Autor:
Julian A. Rees, Stefan Stoll, Guang Yang, Xianru Sun, Marc C. Piquette, Maksym A. Dedushko, Ellen C. Hayes, Julie A. Kovacs, Audra Johansen, Elena V. Rybak-Akimova, Santiago Toledo, Penny Chaau Yan Poon
Publikováno v:
Journal of the American Chemical Society. 141(38)
Herein we quantitatively investigate how metal ion Lewis acidity and steric properties influence the kinetics and thermodynamics of dioxygen binding versus release from structurally analogous Mn–O2...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68cdf405b05bf128b8f786307964c346
https://pubmed.ncbi.nlm.nih.gov/31480847
https://pubmed.ncbi.nlm.nih.gov/31480847
Autor:
Maike N, Blakely, Maksym A, Dedushko, Penny Chaau, Yan Poon, Gloria, Villar-Acevedo, Julie A, Kovacs
Publikováno v:
Journal of the American Chemical Society. 141(5)
Herein, we describe an alkyl thiolate-ligated iron complex that reacts with dioxygen to form an unprecedented example of an iron superoxo (O(2)(•−)) intermediate, [Fe(III)(S(2)(Me2)N(3)(Pr,Pr))(O(2))] (4), which is capable of cleaving strong C–
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::76ee1e9518735d969b4bb39b2f52f4d3
https://pubmed.ncbi.nlm.nih.gov/30661357
https://pubmed.ncbi.nlm.nih.gov/30661357