Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Maksym, Misyura"'
Autor:
Ozge Ceyhan-Birsoy, Elise Fiala, Satshil Rana, Margaret Sheehan, Jennifer Kennedy, Zarina Yelskaya, Vikas Rai, Yirong Li, Ciyu Yang, Donna Wong, Ivelise Rijo, Jacklyn Casanova, Joshua Somar, Nikita Mehta, Hyeonjin Park, Silvana Ostafi, Kanika Arora, Angelika Padunan, Mark D. Ewalt, Umut Aypar, Panieh Terraf, Maksym Misyura, Sofia Haque, Gerald G. Behr, Tamanna Haque, Maria Sulis, Mark B. Geyer, Christopher Forlenza, Meghan C. Thompson, Maria Carlo, Alicia Latham, Ying Liu, Ahmet Zehir, Rose Brannon, Michael Berger, Luis A Diaz Jr, Ahmet Dogan, Marc Ladanyi, Kseniya Petrova-Drus, Khedoudja Nafa, Kenneth Offit, Maria Arcila, Zsofia K. Stadler, Michael F. Walsh, Diana Mandelker
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Not available.
Externí odkaz:
https://doaj.org/article/f666218e110145a987b006840114e720
Autor:
Diana Mandelker, Antonio Marra, Nikita Mehta, Pier Selenica, Zarina Yelskaya, Ciyu Yang, Joshua Somar, Miika Mehine, Maksym Misyura, Olca Basturk, Alicia Latham, Maria Carlo, Michael Walsh, Zsofia K. Stadler, Kenneth Offit, Chaitanya Bandlamudi, Meera Hameed, Ping Chi, Jorge S. Reis-Filho, Ozge Ceyhan-Birsoy
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-6 (2023)
Abstract Traditional genetic testing for patients with gastrointestinal stromal tumors (GISTs) focus on those with syndromic features. To assess whether expanded genetic testing of GIST patients could identify hereditary cancer predisposition, we ana
Externí odkaz:
https://doaj.org/article/8ed49bc9d2174d23ac73af0621960d66
Autor:
Ozge Ceyhan-Birsoy, Gowtham Jayakumaran, Yelena Kemel, Maksym Misyura, Umut Aypar, Sowmya Jairam, Ciyu Yang, Yirong Li, Nikita Mehta, Anna Maio, Angela Arnold, Erin Salo-Mullen, Margaret Sheehan, Aijazuddin Syed, Michael Walsh, Maria Carlo, Mark Robson, Kenneth Offit, Marc Ladanyi, Jorge S. Reis-Filho, Zsofia K. Stadler, Liying Zhang, Alicia Latham, Ahmet Zehir, Diana Mandelker
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-13 (2022)
Abstract Background Genetic testing (GT) for hereditary cancer predisposition is traditionally performed on selected genes based on established guidelines for each cancer type. Recently, expanded GT (eGT) using large hereditary cancer gene panels unc
Externí odkaz:
https://doaj.org/article/b27ebc51933945dda60cc3917da9b260
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 11, Iss 2, Pp n/a-n/a (2023)
Abstract Background Germline variants in the DNA mismatch repair (MMR) genes (MLH1, MSH2, MSH6, and PMS2) cause Lynch syndrome, an autosomal dominant hereditary cancer susceptibility syndrome. The risk for endometrial cancer is significantly higher i
Externí odkaz:
https://doaj.org/article/5f5b5db9029c43c68562281eb0dd665e
Autor:
Sushmita Gordhandas, Eric Rios-Doria, Karen A Cadoo, Amanda Catchings, Anna Maio, Yelena Kemel, Margaret Sheehan, Megha Ranganathan, Dina Green, Anjali Aryamvally, Angela G Arnold, Erin Salo-Mullen, Beryl Manning-Geist, Tiffany Sia, Pier Selenica, Arnaud Da Cruz Paula, Chad Vanderbilt, Maksym Misyura, Mario M Leitao, Jennifer J Mueller, Vicky Makker, Maria Rubinstein, Claire F Friedman, Qin Zhou, Alexia Iasonos, Alicia Latham, Maria I Carlo, Yonina R Murciano-Goroff, Marie Will, Michael F Walsh, Shirin Issa Bhaloo, Lora H Ellenson, Ozge Ceyhan-Birsoy, Michael F Berger, Mark E Robson, Nadeem Abu-Rustum, Carol Aghajanian, Kenneth Offit, Zsofia Stadler, Britta Weigelt, Diana L Mandelker, Ying L Liu
Publikováno v:
JNCI: Journal of the National Cancer Institute. 115:560-569
Background We sought to determine the prevalence of germline pathogenic variants (gPVs) in unselected patients with endometrial cancer (EC), define biallelic gPVs within tumors, and describe their associations with clinicopathologic features. Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec9f316b2b3f5be8abdd95005032897d
https://doi.org/10.1093/jnci/djad016
https://doi.org/10.1093/jnci/djad016
Autor:
Tony El Jabbour, Maksym Misyura, Darren Cowzer, Michal Zimmermann, Victoria Rimkunas, Antonio Marra, Fatemeh Derakhshan, Pier Selenica, Megan Parilla, Jeremy S Setton, Ozge Ceyhan-Birsoy, Yelena Kemel, Amanda Catchings, Megha Ranganathan, Geoffrey Y Ku, Yelena Y Janjigian, Michael Zinda, Maria Koehler, Zsofia Stadler, Jinru Shia, Jorge S Reis-Filho, Diana Mandelker
Publikováno v:
JNCI: Journal of the National Cancer Institute. 114:761-770
Background Gastroesophageal junction (GEJ) adenocarcinoma is a rare cancer associated with poor prognosis. The genetic factors conferring predisposition to GEJ adenocarcinoma have yet to be identified. Methods We analyzed germline testing results fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b85ad2a13b42b7896a45a3e66f90a566
https://doi.org/10.1093/jnci/djac024
https://doi.org/10.1093/jnci/djac024
Autor:
Jorge S. Reis-Filho, Pamela Drullinsky, Maksym Misyura, Liying Zhang, Vikas Rai, Edaise M da Silva, Britta Weigelt, Jinru Shia, Hong Zhang, Edi Brogi, Joshua Z. Drago, Mark E. Robson, Antonio Marra, Christopher J Schwartz, Pedram Razavi, Hannah Y Wen, Andrea Gazzo, Diana Mandelker, Pier Selenica, Timothy M. D'Alfonso, Fresia Pareja
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research, vol 28, iss 2
Purpose: Lynch syndrome is defined by germline pathogenic mutations involving DNA mismatch repair (MMR) genes and linked with the development of MMR-deficient colon and endometrial cancers. Whether breast cancers developing in the context of Lynch sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a05be915840cecaa209162dce7dea1a8
https://doi.org/10.1158/1078-0432.ccr-21-2027
https://doi.org/10.1158/1078-0432.ccr-21-2027
Autor:
Hong Zhang, Jorge S. Reis-Filho, Jinru Shia, Britta Weigelt, Liying Zhang, Hannah Y. Wen, Joshua Z. Drago, Mark E. Robson, Pedram Razavi, Pamela Drullinsky, Edi Brogi, Timothy M. D'Alfonso, Maksym Misyura, Fresia Pareja, Diana Mandelker, Vikas K. Rai, Pier Selenica, Andrea M. Gazzo, Antonio Marra, Edaise M. da Silva, Christopher J. Schwartz
Supplementary Figure 1. Comparison of tumor mutational burden, dominant mutational signatures and MSISensor scores of Lynch syndrome BC cohort to control-matched BC cohort using MSK-IMPACT targeted sequencing.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b26cfd94978536f620e96061187e5a1
https://doi.org/10.1158/1078-0432.22482035.v1
https://doi.org/10.1158/1078-0432.22482035.v1
Autor:
Hong Zhang, Jorge S. Reis-Filho, Jinru Shia, Britta Weigelt, Liying Zhang, Hannah Y. Wen, Joshua Z. Drago, Mark E. Robson, Pedram Razavi, Pamela Drullinsky, Edi Brogi, Timothy M. D'Alfonso, Maksym Misyura, Fresia Pareja, Diana Mandelker, Vikas K. Rai, Pier Selenica, Andrea M. Gazzo, Antonio Marra, Edaise M. da Silva, Christopher J. Schwartz
Supplementary Legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2921032a7c70c4891b9d8d45ae1d5c3b
https://doi.org/10.1158/1078-0432.22482032
https://doi.org/10.1158/1078-0432.22482032
Autor:
David B. Solit, Angela G. Arnold, Mark E. Robson, Diana Mandelker, Michael F. Berger, Shweta S. Chavan, Maksym Misyura, Michael Walsh, Anna Maio, Sarah R. Kane, Karen Cadoo, Yelena Kemel, Preethi Srinivasan, Ying Liu, Jinru Shia, Kenneth Offit, Kelsey Breen, Jennifer Kennedy, Margaret Sheehan, Semanti Mukherjee, Caitlin Bourque, Chaitanya Bandlamudi, Zalak Patel, Maria I. Carlo, Zsofia K. Stadler, Amanda Catchings, Erin E. Salo-Mullen, Arnold J. Markowitz, Barry S. Taylor, Prince Rainier Tejada, Rosalba Sacca, Vanessa Marcell, Alicia Latham, Ozge Ceyhan-Birsoy, Mark T.A. Donoghue, Kimberly Amoroso, Megha Ranganathan
Publikováno v:
JCO Precision Oncology. :455-465
PURPOSE NTHL1 and MSH3 have been implicated as autosomal recessive cancer predisposition genes. Although individuals with biallelic NTHL1 and MSH3 pathogenic variants (PVs) have increased cancer and polyposis risk, risks for monoallelic carriers are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ba859253338af25f8aa87589967d494
https://doi.org/10.1200/po.20.00443
https://doi.org/10.1200/po.20.00443