Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Maksim Sorokin"'
Autor:
Aleksey Drobyshev, Alexander Modestov, Maria Suntsova, Elena Poddubskaya, Alexander Seryakov, Aleksey Moisseev, Maksim Sorokin, Victor Tkachev, Galina Zakharova, Aleksander Simonov, Marianna A. Zolotovskaia, Anton Buzdin
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
The TERT gene encodes the reverse transcriptase subunit of telomerase and is normally transcriptionally suppressed in differentiated human cells but reactivated in cancers where its expression is frequently associated with poor survival prognosis. He
Externí odkaz:
https://doaj.org/article/3dc19069f31e4c6d85a36102e9c4f88d
Autor:
Annamaria Salvati, Carlo Ferravante, Jessica Lamberti, Teresa Rocco, Elena Alexandrova, Ylenia D’Agostino, Maksim Sorokin, Victor Efimov, Anton Buzdin, Oriana Strianese, Giovanni Nassa, Roberta Tarallo, Alessandro Weisz, Francesca Rizzo, Giorgio Giurato
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-6 (2023)
Abstract The ongoing COVID-19 pandemic caused by SARS-CoV-2 has affected millions of people worldwide and has significant implications for public health. Host transcriptomics profiling provides comprehensive understanding of how the virus interacts w
Externí odkaz:
https://doaj.org/article/91fe694c20ef40d6a40d21a5214d6443
Autor:
Maksim Sorokin, Anton A. Buzdin, Anastasia Guryanova, Victor Efimov, Maria V. Suntsova, Marianna A. Zolotovskaia, Elena V. Koroleva, Marina I. Sekacheva, Victor S. Tkachev, Andrew Garazha, Kristina Kremenchutckaya, Aleksey Drobyshev, Aleksander Seryakov, Alexander Gudkov, Irina V. Alekseenko, Olga Rakitina, Maria B. Kostina, Uliana Vladimirova, Aleksey Moisseev, Dmitry Bulgin, Elena Radomskaya, Viktor Shestakov, Vladimir P. Baklaushev, Vladimir Prassolov, Petr V. Shegay, Xinmin Li, Elena V. Poddubskaya, Nurshat Gaifullin
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 3964-3986 (2023)
Normal tissues are essential for studying disease-specific differential gene expression. However, healthy human controls are typically available only in postmortal/autopsy settings. In cancer research, fragments of pathologically normal tissue adjace
Externí odkaz:
https://doaj.org/article/bf4fa9cc991740c98706b792903a2914
Author Correction: Host nasopharyngeal transcriptome dataset of a SARS-CoV-2 positive Italian cohort
Autor:
Annamaria Salvati, Carlo Ferravante, Jessica Lamberti, Teresa Rocco, Elena Alexandrova, Ylenia D’Agostino, Maksim Sorokin, Victor Efimov, Anton Buzdin, Oriana Strianese, Giovanni Nassa, Roberta Tarallo, Alessandro Weisz, Francesca Rizzo, Giorgio Giurato
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/9196279123a0441a9f4525359e2d665c
Autor:
Dmitri Kamashev, Nina Shaban, Timofey Lebedev, Vladimir Prassolov, Maria Suntsova, Mikhail Raevskiy, Nurshat Gaifullin, Marina Sekacheva, Andrew Garazha, Elena Poddubskaya, Maksim Sorokin, Anton Buzdin
Publikováno v:
Cells, Vol 12, Iss 16, p 2022 (2023)
Regardless of the presence or absence of specific diagnostic mutations, many cancer patients fail to respond to EGFR-targeted therapeutics, and a personalized approach is needed to identify putative (non)responders. We found previously that human per
Externí odkaz:
https://doaj.org/article/cc171a525c3147a3bb34a7b594038ae2
Autor:
Maksim Sorokin, Elizaveta Rabushko, Julian Markovich Rozenberg, Tharaa Mohammad, Aleksander Seryakov, Marina Sekacheva, Anton Buzdin
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 14 (2022)
Mechanistically, chimeric genes result from DNA rearrangements and include parts of preexisting normal genes combined at the genomic junction site. Some rearranged genes encode pathological proteins with altered molecular functions. Those which can a
Externí odkaz:
https://doaj.org/article/bbab0c6157444c219d2d71368a0cbd7d
Autor:
Galina Zakharova, Alexander Modestov, Polina Pugacheva, Rijalda Mekic, Ekaterina Savina, Anastasia Guryanova, Anastasia Rachkova, Semyon Yakushov, Andrei Alimov, Elizaveta Kulaeva, Elena Fedoseeva, Artem Kleyman, Kirill Vasin, Victor Tkachev, Andrew Garazha, Marina Sekacheva, Maria Suntsova, Maksim Sorokin, Anton Buzdin, Marianna A. Zolotovskaia
Publikováno v:
Cells, Vol 12, Iss 9, p 1299 (2023)
The evolution of protein-coding genes has both structural and regulatory components. The first can be assessed by measuring the ratio of non-synonymous to synonymous nucleotide substitutions. The second component can be measured as the normalized pro
Externí odkaz:
https://doaj.org/article/5f431455d424499cbdaf6d370bea8919
Autor:
Alexander Gudkov, Valery Shirokorad, Kirill Kashintsev, Dmitriy Sokov, Daniil Nikitin, Andrey Anisenko, Nicolas Borisov, Marina Sekacheva, Nurshat Gaifullin, Andrew Garazha, Maria Suntsova, Elena Koroleva, Anton Buzdin, Maksim Sorokin
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Sorafenib is a tyrosine kinase inhibitory drug with multiple molecular specificities that is approved for clinical use in second-line treatments of metastatic and advanced renal cell carcinomas (RCCs). However, only 10–40% of RCC patients respond o
Externí odkaz:
https://doaj.org/article/11eb036dc7a1466a8a58577ee04938d9
Autor:
Maksim Sorokin, Elizaveta Rabushko, Victor Efimov, Elena Poddubskaya, Marina Sekacheva, Alexander Simonov, Daniil Nikitin, Aleksey Drobyshev, Maria Suntsova, Anton Buzdin
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Microsatellite instability (MSI) is an important diagnostic and prognostic cancer biomarker. In colorectal, cervical, ovarian, and gastric cancers, it can guide the prescription of chemotherapy and immunotherapy. In laboratory diagnostics of suscepti
Externí odkaz:
https://doaj.org/article/acc6c406b73b4c85a65a3ca797d6170a
Autor:
Galina Zakharova, Victor Efimov, Mikhail Raevskiy, Pavel Rumiantsev, Alexander Gudkov, Oksana Belogurova-Ovchinnikova, Maksim Sorokin, Anton Buzdin
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 157 (2022)
In 2021, the fifth edition of the WHO classification of tumors of the central nervous system (WHO CNS5) was published. Molecular features of tumors were directly incorporated into the diagnostic decision tree, thus affecting both the typing and stagi
Externí odkaz:
https://doaj.org/article/285549f8cfbe40048b8245d83f644bd6