Zobrazeno 1 - 10
of 245
pro vyhledávání: '"Makoto Usami"'
Publikováno v:
Biochemistry and Biophysics Reports, Vol 38, Iss , Pp 101681- (2024)
Myeloid differentiation factor 88 (MyD88), which is a key regulator of nuclear factor kappa B (NF-κB), plays an important role in tumorigenesis in lymphoid malignancies such as Waldenstrom's macroglobulinemia (WM). However, its biological function i
Externí odkaz:
https://doaj.org/article/6dc3db066b764e5284bcecac4dca5e4f
Autor:
Michihiro Ono, Yuki Ikeda, Ginji Ohmori, Yohei Arihara, Ryo Shibuya, Atsushi Uesugi, Shutaro Oiwa, Ryo Ito, Makoto Usami, Michiko Yamada, Tomoyuki Abe, Masahiro Maeda
Publikováno v:
DEN Open, Vol 4, Iss 1, Pp n/a-n/a (2024)
Abstract Endoscopic ultrasound‐guided gallbladder drainage for patients with cholecystitis and high surgical risk is commonly performed by dilating the fistula before inserting the delivery sheath; however, this carries an increased risk of periton
Externí odkaz:
https://doaj.org/article/037a92fc7321423eaa56d71968b6a9a4
Autor:
Hajime Nakamura, Aika Shionoya, Yohei Arihara, Naotaka Hayasaka, Tomohiro Kubo, Makoto Usami, Shintaro Sugita, Hisashi Uhara, Kohichi Takada
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Ipilimumab plus nivolumab therapy is approved for patients with unresectable advanced esophageal squamous cell carcinoma (ESCC). Although a combination of immune checkpoint inhibitors (ICIs), compared to conventional chemotherapy, can improve overall
Externí odkaz:
https://doaj.org/article/a32a04531e6a4771a5e78302cc7dbcb6
Publikováno v:
Journal of Pharmacological Sciences, Vol 150, Iss 4, Pp 233-243 (2022)
N-Methyl-D-aspartate receptors (NMDARs) in the brain are influenced by psychoactive drugs such as 2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one (ketamine) and its analog 2-(ethylamino)-2-(3-methoxyphenyl)-cyclohexanone (methoxetamine). The recre
Externí odkaz:
https://doaj.org/article/fc93e92edd564969b33ee9c3eb0669f2
Publikováno v:
Chemical Engineering Transactions, Vol 89 (2021)
Da Nang is a city with rapid growth and expansion, along with it is pressure for municipal solid waste treatment. Within a decade, waste generation from commercial and service activities increased significantly at a rate of 9 %/y and reached 1.073 t/
Externí odkaz:
https://doaj.org/article/4ed7aa4c36d145a098e8eb5de20023db
Autor:
Atsuko Miyajima, Yukie Kuroda, Kazue Sakemi-Hoshikawa, Makoto Usami, Katsuyoshi Mitsunaga, Tomohiko Irie, Yasuo Ohno, Momoko Sunouchi
Publikováno v:
Toxicology Reports, Vol 7, Iss , Pp 979-985 (2020)
Effects of 4-methyl-2-mercaptobenzimidazole (4-MeMBI) and 5-methyl-2- mercaptobenzimidazole (5-MeMBI) on cytochrome P450 (CYP) activity were examined in primary cultured rat hepatocytes. Hepatocytes from male Wistar rats were cultured in the presence
Externí odkaz:
https://doaj.org/article/2baa9904a5d44238b2664d345c8d630b
Autor:
Yuka Koga, Noriaki Maeshige, Hiroto Tabuchi, Mikiko Uemura, Michiko Aoyama-Ishikawa, Makoto Miyoshi, Chikako Katakami, Makoto Usami
Publikováno v:
International Journal of Ophthalmology, Vol 10, Iss 9, Pp 1337-1343 (2017)
AIM: To evaluate the antifibrogenic effects of butyrate or phenylbutyrate, a chemical derivative of butyrate, in human pterygium fibroblasts. METHODS: Human pterygium fibroblasts obtained from patient pterygium tissue were treated with butyrate or p
Externí odkaz:
https://doaj.org/article/6dedc92272464ee984852f89aeb06e0f
Autor:
Kazuhiro Torii, Noriaki Maeshige, Michiko Aoyama-Ishikawa, Makoto Miyoshi, Hiroto Terashi, Makoto Usami
Publikováno v:
Anais Brasileiros de Dermatologia, Vol 92, Iss 2, Pp 184-190 (2017)
Abstract: Background: A single, effective therapeutic regimen for keloids has not been established yet, and the development of novel therapeutic approaches is expected. Butyrate, a short-chain fatty acid, and docosahexaenoic acid (DHA), a ω-3 polyun
Externí odkaz:
https://doaj.org/article/52037dde83f244babd776ad1512d678d
Autor:
Yutaka Okagawa, Kohichi Takada, Yohei Arihara, Shohei Kikuchi, Takahiro Osuga, Hajime Nakamura, Yusuke Kamihara, Naotaka Hayasaka, Makoto Usami, Kazuyuki Murase, Koji Miyanishi, Masayoshi Kobune, Junji Kato
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0168355 (2016)
The prognosis of advanced hepatocellular carcinoma (HCC) is dismal, underscoring the need for novel effective treatments. The α1,6-fucosyltransferase (fucosyltransferase 8, FUT8) has been reported to accelerate malignant potential in HCC. Our study
Externí odkaz:
https://doaj.org/article/acd7f4c323864e468acf96834d1a4e46
Autor:
Hikaru Nishida, Ayaka Ikegami, Chiaki Kaneko, Hitomi Kakuma, Hisano Nishi, Noriko Tanaka, Michiko Aoyama, Makoto Usami, Yasuhiko Okimura
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128805 (2015)
Branched-chain amino acids (BCAAs) and IGF-I, the secretion of which is stimulated by growth hormone (GH), prevent muscle atrophy. mTOR plays a pivotal role in the protective actions of BCAA and IGF-1. The pathway by which BCAA activates mTOR is diff
Externí odkaz:
https://doaj.org/article/e9e48f37651e439baab46481d177ac34