Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Makoto Take"'
Autor:
Makoto Take1 makoto-take@jbrc.johas.go.jp, Tetsuya Takeuchi1, Shigeyuki Hirai1, Kenji Takanobu1, Michiharu Matsumoto1, Shoji Fukushima1, Jun Kanno1
Publikováno v:
Journal of Toxicological Sciences. Apr2017, Vol. 42 Issue 2, p121-128. 8p.
Autor:
Shoji Fukushima, Makoto Take, Tomoki Takeda, Hiroaki Ishikawa, Michiharu Matsumoto, Kasuke Nagano
Publikováno v:
Journal of environmental science and health. Part A, Toxic/hazardous substancesenvironmental engineering. 55(14)
For human risk assessment of toxic chemicals, especially volatile organic compounds (VOCs), the Ministry of the Environment, Government of Japan, has called for the interconversion of inhalation-dose and oral-dose data, two common exposure routes. To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5469f3268e03640944bfa1523d484580
https://pubmed.ncbi.nlm.nih.gov/33054527
https://pubmed.ncbi.nlm.nih.gov/33054527
Autor:
Takashi Mine, Makoto Take, Michiharu Matsumoto, Hideki Senoh, Shoji Fukushima, Taku Katagiri, Kenji Takanobu, Misae Saito, Shigetoshi Aiso, Hiroaki Ishikawa, Naoki Ikawa, Mitsuru Haresaku, Yumi Umeda
Publikováno v:
SANGYO EISEIGAKU ZASSHI. 57:85-96
INTRODUCTION We investigated the 2-year survival rate and incidence of spontaneous tumors in F344/DuCrlCrlj rats used in carcinogenicity studies of chemical substances. Records for animals used in the control groups of carcinogenicity studies which w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f722ce9dedd495d24f40ff0ff168a2d8
https://doi.org/10.1539/sangyoeisei.e14006
https://doi.org/10.1539/sangyoeisei.e14006
Autor:
Shoji Fukushima, Kenji Takanobu, Shigeyuki Hirai, Jun Kanno, Michiharu Matsumoto, Tetsuya Takeuchi, Makoto Take
Publikováno v:
The Journal of toxicological sciences. 42(2)
The present investigation was undertaken to determine the distribution of 1,2-dichloropropane (DCP) in the blood, liver, kidney, lung, and abdominal fat of rats after oral administration. Male rats were orally administered 62 or 125 mg/kg body weight
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ce29f8937248510ad36c4ff59192170
https://pubmed.ncbi.nlm.nih.gov/28321038
https://pubmed.ncbi.nlm.nih.gov/28321038
Distribution of blood and tissue concentrations in rats by inhalation exposure to 1,2-dichloroethane
Autor:
Seigo Yamamoto, Kasuke Nagano, Tetsuya Takeuchi, Michiharu Matsumoto, Shoji Fukushima, Kenji Takanobu, Mitsuru Haresaku, Makoto Take
Publikováno v:
Journal of Environmental Science and Health, Part A. 48:1031-1036
The compound 1,2-dichloroethane (DCE) is a ubiquitous environmental contaminant. The primary route of exposure of humans to DCE is inhalation of its vapor. The present investigation was undertaken to determine the distribution and accumulation of DCE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7ee922a10f82362a771b068209c3007
https://doi.org/10.1080/10934529.2013.773765
https://doi.org/10.1080/10934529.2013.773765
Publikováno v:
Inhalation Toxicology. 25:435-443
The subchronic toxicity and carcinogenicity of 1,2-dichloropropane (DCP) in male and female B6D2F1 mice exposed to DCP by inhalation for 13 weeks or for 2 years was investigated. The DCP concentrations used were 50, 100, 200, 300 or 400 ppm (v/v) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d10fadf4668aa46ed8edc8738e4fd04f
https://doi.org/10.3109/08958378.2013.800618
https://doi.org/10.3109/08958378.2013.800618
Autor:
Takashi Hirota, Makoto Ohnishi, Makoto Take, Seigo Yamamoto, Shoji Fukushima, Michiharu Matsumoto, Kasuke Nagano
Publikováno v:
Journal of Environmental Science and Health, Part A. 45:1616-1624
The present investigation was undertaken to determine the distribution and accumulation of chloroform in the blood, liver, kidney and abdominal fat of rats after simultaneous exposure by two routes, inhalation and oral. To distinguish the contributio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::455d0f3b90b5c2e6394f58b000266bbe
https://doi.org/10.1080/10934529.2010.506121
https://doi.org/10.1080/10934529.2010.506121
Publikováno v:
The Journal of Toxicological Sciences. 34:233-237
Oral administration of 2,4-dichloro-1-nitrobenzene (2,4-DCNB) causes kidney tumors in the rat. The objective of the present study was to identify the chemical structure of 2,4-DCNB metabolites in urine. Urine from 2,4-DCNB fed rats was more yellow th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc5c963a759c65a5b084368994a581be
https://doi.org/10.2131/jts.34.233
https://doi.org/10.2131/jts.34.233
Design and performance of a system for blood collection of rats under whole-body inhalation exposure
Publikováno v:
The Journal of Toxicological Sciences. 34:221-226
In order to obtain basic risk assessment data on human health exposure to volatile organic compound (VOC) vapor by inhalation, a whole-body inhalation exposure system which allows blood collection during the exposure period was designed. The system w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd9eade4cac4356b8c1118a5a2dfcf16
https://doi.org/10.2131/jts.34.221
https://doi.org/10.2131/jts.34.221
Autor:
Shoji Fukushima, Michiharu Matsumoto, Tatsuya Kasai, Hideki Senoh, Shigetoshi Aiso, Makoto Take, Yumi Umeda
Publikováno v:
Inhalation toxicology. 26(8)
The carcinogenicity of inhaled dichloromethane (DCM) was examined by exposing groups of 50 F344/DuCrj rats and 50 Crj: BDF1 mice of both sexes to 0, 1000, 2000, or 4000 ppm (w/w) DCM-containing aerosol for 2 years. Inhalation of DCM resulted in incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b67a3dfd0f553180b054191d1f27120
https://pubmed.ncbi.nlm.nih.gov/24909451
https://pubmed.ncbi.nlm.nih.gov/24909451