Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Makoto Shimozawa"'
Autor:
Kaori Kanemaru, Makoto Shimozawa, Manabu Kitamata, Rikuto Furuishi, Hinako Kayano, Yui Sukawa, Yuuki Chiba, Takatsugu Fukuyama, Junya Hasegawa, Hiroki Nakanishi, Takuma Kishimoto, Kazuya Tsujita, Kazuma Tanaka, Toshiki Itoh, Junko Sasaki, Takehiko Sasaki, Kiyoko Fukami, Yoshikazu Nakamura
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Epithelial cells provide cell-cell adhesion to maintain the integrity of multicellular organisms. Here the authors show that phospholipid phosphatidylinositol (4,5)-bisphosphate is critical for the maintenance of epithelial characteristics.
Externí odkaz:
https://doaj.org/article/7823ce0d20e645f189c00d1084489ae8
Autor:
Dina Medina-Vera, Hongjing Zhao, Erika Bereczki, Cristina Rosell-Valle, Makoto Shimozawa, Gefei Chen, Fernando Rodríguez de Fonseca, Per Nilsson, Simone Tambaro
Publikováno v:
Biology, Vol 12, Iss 6, p 805 (2023)
Background: The endocannabinoid system (ECS) and associated lipid transmitter-based signaling systems play an important role in modulating brain neuroinflammation. ECS is affected in neurodegenerative disorders, such as Alzheimer’s disease (AD). He
Externí odkaz:
https://doaj.org/article/97e68dfdb67d4382b3c85ca13d2c9f52
Autor:
Richeng Jiang, Makoto Shimozawa, Johanna Mayer, Simone Tambaro, Rakesh Kumar, Axel Abelein, Bengt Winblad, Nenad Bogdanovic, Per Nilsson
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Alzheimer’s disease (AD) is characterized by impaired protein homeostasis leading to amyloid-β peptide (Aβ) amyloidosis. Amyloid precursor protein (APP) knock-in mice exhibit robust Aβ pathology, providing possibilities to determine its effect o
Externí odkaz:
https://doaj.org/article/5bdec84212d44e5484c5d22672a15608
Autor:
Luana Naia, Catarina M. Pinho, Giacomo Dentoni, Jianping Liu, Nuno Santos Leal, Duarte M. S. Ferreira, Bernadette Schreiner, Riccardo Filadi, Lígia Fão, Niamh M. C. Connolly, Pontus Forsell, Gunnar Nordvall, Makoto Shimozawa, Elisa Greotti, Emy Basso, Pierre Theurey, Anna Gioran, Alvin Joselin, Marie Arsenian-Henriksson, Per Nilsson, A. Cristina Rego, Jorge L. Ruas, David Park, Daniele Bano, Paola Pizzo, Jochen H. M. Prehn, Maria Ankarcrona
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-21 (2021)
Abstract Background Mitochondrial dysfunction is a common feature of aging, neurodegeneration, and metabolic diseases. Hence, mitotherapeutics may be valuable disease modifiers for a large number of conditions. In this study, we have set up a large-s
Externí odkaz:
https://doaj.org/article/4aff891322844c2cbd9f607edd6e7c04
Autor:
Yuji Naito, Makoto Shimozawa, Hiroki Manabe, Masaaki Kuroda, Naoya Tomatsuri, Kazuhiko Uchiyama, Tomohisa Takagi, Norimasa Yoshida, Toshikazu Yoshikawa
Publikováno v:
Biological Research, Vol 37, Iss 2, Pp 231-238 (2004)
Red wine polyphenolic compounds have been demonstrated to possess antioxidant properties, and several studies have suggested that they might constitute a relevant dietary factor in the protection from coronary heart disease. The aim of the present st
Externí odkaz:
https://doaj.org/article/a9733c363e4f4f9eb206ad0a4eab620c
Autor:
Tambaro, Dina Medina-Vera, Hongjing Zhao, Erika Bereczki, Cristina Rosell-Valle, Makoto Shimozawa, Gefei Chen, Fernando Rodríguez de Fonseca, Per Nilsson, Simone
Publikováno v:
Biology; Volume 12; Issue 6; Pages: 805
Background: The endocannabinoid system (ECS) and associated lipid transmitter-based signaling systems play an important role in modulating brain neuroinflammation. ECS is affected in neurodegenerative disorders, such as Alzheimer’s disease (AD). He
Autor:
Luana Naia, Makoto Shimozawa, Erika Bereczki, Xidan Li, Jianping Liu, Richeng Jiang, Nuno Santos Leal, Catarina Moreira Pinho, Erik Berger, Victoria Lim Falk, Giacomo Dentoni, Maria Ankarcrona, Per Nilsson
Increased amyloid β-peptide (Aβ) level is one of the drivers of Alzheimer’s disease (AD). Amyloid precursor protein (App) knock-in mice recapitulate the human Aβ pathology, allowing the elucidation of the downstream effects of Aβ and their temp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfbd5fff7ae9a7942aea1145d6bbd7ad
https://doi.org/10.1101/2023.03.07.531542
https://doi.org/10.1101/2023.03.07.531542
Autor:
Helene Tigro, Makoto Shimozawa, Per Nilsson, Alexey Lyashkov, Mohammed Khadeer, Ivar Järving, Luigi Ferrucci, Ruth Shimmo, Jan Johansson, Ruin Moaddel
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 232:115465
Autor:
Jiesi Wang, Bai Lu, Wei Zhang, Xi Chen, Weiwen Wang, Bengt Winblad, Johanna Mayer, Ailing Yang, Simone Tambaro, Hua Han, Liu J, Zhengyi Yang, Man Li, Tianzi Jiang, Keliang Pang, Per Nilsson, Wei Guo, Richeng Jiang, Hang Liu, B. Zhang, Linlin Li, Makoto Shimozawa
Publikováno v:
Cell Research
A major obstacle in Alzheimer’s disease (AD) research is the lack of predictive and translatable animal models that reflect disease progression and drug efficacy. Transgenic mice overexpressing amyloid precursor protein (App) gene manifest non-phys
Autor:
Richeng, Jiang, Makoto, Shimozawa, Johanna, Mayer, Simone, Tambaro, Rakesh, Kumar, Axel, Abelein, Bengt, Winblad, Nenad, Bogdanovic, Per, Nilsson
Publikováno v:
Frontiers in aging neuroscience. 14
Alzheimer's disease (AD) is characterized by impaired protein homeostasis leading to amyloid-β peptide (Aβ) amyloidosis. Amyloid precursor protein (APP) knock-in mice exhibit robust Aβ pathology, providing possibilities to determine its effect on