Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Makoto Rembutsu"'
Autor:
Shuhei Kanagaki, Yusuke Tsutsui, Naoki Kobayashi, Takashi Komine, Minoru Ito, Yunike Akasaka, Michiaki Nagasawa, Tomohiro Ide, Naoki Omae, Kazuhisa Nakao, Makoto Rembutsu, Maki Iwago, Aki Yonezawa, Yusei Hosokawa, Tetsuya Hosooka, Wataru Ogawa, Koji Murakami
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106293- (2023)
Summary: 5′-Adenosine monophosphate-activated protein kinase (AMPK) is a potential therapeutic target for various medical conditions. We here identify a small-molecule compound (RX-375) that activates AMPK and inhibits fatty acid synthesis in cultu
Externí odkaz:
https://doaj.org/article/a92b50733fa44d83b46f3299ab983040
Autor:
Marc P.M. Soutar, Martin Balastik, Lidy van Aalten, Adam R. Cole, Makoto Rembutsu, Hilary McLauchlan, C. James Hastie, Mark Peggie, Calum Sutherland, Kun Ping Lu
Publikováno v:
Journal of Biological Chemistry. 283:18227-18237
Collapsin response mediator protein 2 (CRMP2) binds to microtubules and regulates axon outgrowth in neurons. This action is regulated by sequential phosphorylation by the kinases cyclin-dependent kinase 5 (Cdk5) and glycogen synthase kinase 3 (GSK3)
Autor:
Lidy van Aalten, Marc P.M. Soutar, and Adam R. Cole, Hilary McLauchlan, C. James Hastie, Calum Sutherland, Robert Gourlay, Makoto Rembutsu, Nicholas A. Morrice
Publikováno v:
Biochemistry. 47(7)
The identification of phosphorylation state-dependent interacting proteins provides clues as to the function of the phosphorylation. Techniques such as yeast two hybrid and co-immunoprecipitation do not employ a single species of fully phosphorylated