Zobrazeno 1 - 10 of 23 pro vyhledávání: '"Makoto Ogino"'
1
Differences in Transactivation between Rat CYP3A1 and Human CYP3A4 Genes by Human Pregnane X Receptor
Autor: Yasushi Yamazoe, Miki Shimada, Makoto Ogino, Tomonari Takada, Masaaki Miyata, Kiyoshi Nagata
Publikováno v: Drug Metabolism and Pharmacokinetics. 19:103-113
In an assay system using a human CYP3A4 reporter constructed with the promoter (+11 nt to -362 nt) and enhancer (-7.2 knt to -7.8 knt) regions including everted repeat separated by six nucleotides (ER-6) and direct repeat separated by three nucleotid
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13c5f5b5a074ccd7b51b72091a65ac90
https://doi.org/10.2133/dmpk.19.103
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2
Adenovirus Vector-Mediated Reporter System forIn Vivo Analyses of Human CYP3A4 GeneActivation
Autor: Miki Shimada, Toru Yamazaki, Kiyoshi Nagata, Takayuki Okubo, Yasushi Yamazoe, Masayuki Furukawa, Makoto Ogino
Publikováno v: Journal of Biochemistry. 131:71-78
The use of cultured mammalian cells and artificial promoters for analyses of gene regulation gives results that are sometimes inconsistent with in vivo events and thus inconclusive. To understand the in vivo mechanism of chemically mediated CYP3A4 ge
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ae328c00f1803def6917c4a59871bdf
https://doi.org/10.1093/oxfordjournals.jbchem.a003079
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3
Molecular Mechanism of Human CYP3A4 Induction
Autor: Kiyoshi Nagata, Yasushi Yamazoe, Takayuki Ohkubo, Tomonari Takada, Toru Yamasaki, Makoto Ogino, Masayuki Furukawa
Publikováno v: Drug Metabolism and Pharmacokinetics. 16:485-490
Cytochrome P450s included in CYP3A subfamily are involved in metabolism of numbers of clinically relevant drugs as well as numerous endogenous compounds. CYP3A forms are induced by treatment with various drugs, but clear differences are observed on i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::03af2ba25fcd36b648e0d5b2eb633a6f
https://doi.org/10.2133/dmpk.16.485
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6
Hepatocyte Nuclear Factor 4-Mediated Activation of Rat CYP3A1 Gene and Its Modes of Modulation by Apolipoprotein AI Regulatory Protein I and v-ErbA-Related Protein 3
Autor: Makoto Ogino, Masaaki Miyata, Kiyoshi Nagata, Yasushi Yamazoe
Publikováno v: Archives of Biochemistry and Biophysics. 362:32-37
CYP3A1 gene (P450/6betaB) encodes testosterone 6beta-hydroxylase (EC 1.14.14.1) in rats. The promoter region of CYP3A1 gene contains three binding sites for nuclear factors: 6betaB-A (-105 to -86), 6betaB-B (-139 to -118), and 6betaB-C (-164 to -145)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06b92d3de721c14d138a241d0bc3fb8b
https://doi.org/10.1006/abbi.1998.1012
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7
Molecular Cloning, Expression, and Enzymatic Characterization of Rabbit Hydroxysteroid Sulfotransferase AST-RB2 (ST2A8)
Autor: Ken Ichi Fujita, Miki Shimada, Rika Ueda, Takehisa Hata, Kazuhide Iwasaki, Kiyoshi Nagata, Kouichi Yoshinari, Toshifumi Shiraga, Yasushi Yamazoe, Makoto Ogino
Publikováno v: Journal of Biochemistry. 123:740-746
Cytosolic sulfotransferases, which consist of at least three gene families, play a major role in activation and detoxification of both endogenous and exogenous chemicals. We recently purified a rabbit sulfotransferase, AST-RB2, showing high activitie
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e8905657b5140606b0088d1719086c50
https://doi.org/10.1093/oxfordjournals.jbchem.a021999
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8
Molecular Cloning and Expression of an Amine Sulfotransferase cDNA: A New Gene Family of Cytosolic Sulfotransferases in Mammals
Autor: Kiyoshi Nagata, Kouichi Yoshinari, Makoto Ogino, Kazuhide Iwasaki, Toshifumi Shiraga, Takehisa Hata, Yasushi Yamazoe, Ken Ichi Fujita
Publikováno v: Journal of Biochemistry. 123:479-486
A cDNA of amine sulfotransferase-RB1 (AST-RB1), which efficiently catalyzes 4-phenyl-1,2,3,6-tetrahydropyridine (PTHP) sulfation, has been isolated by immunoscreening of a rabbit liver cDNA library. The cDNA consisted of 1,117 base pairs and encoded
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56afd8acd304a7e39ce99593a1fbacf3
https://doi.org/10.1093/oxfordjournals.jbchem.a021961
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9
Characterization of nodules induced by bioactive glass on cultured periodontal-ligament fibroblasts
Autor: Takeshi Sueda, Makoto Ogino, Tetsuro Kamada, Kohji Kubo, Mayumi Uehara, Takashi Matsuyama, Motoo Kitano, Yuichi Izumi, Nobuyuki Tsukasa
Publikováno v: Journal of Biomedical Materials Research. 29:503-509
We previously reported that materials leached from bioactive glass (BG) and vitamin D3 induced the formation of nodules on cultured periodontal-ligament fibroblasts (PLF). In this study, we have investigated the relationship between the conditions of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a581f5ca7f2547758445551b76da38ab
https://doi.org/10.1002/jbm.820290410
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10
Selective suppressions of human CYP3A forms, CYP3A5 and CYP3A7, by troglitazone in HepG2 cells
Autor: Yasushi Yamazoe, Kiyoshi Nagata, Makoto Ogino
Publikováno v: Drug metabolism and pharmacokinetics. 17(1)
Troglitazone is an insulin sensitizer and also known as an agonist of peroxisome proliferator-activated receptor-gamma (PPARgamma). In the present study, we have studied the influence of troglitazone on CYP3A form expressions in HepG2 cells for a mod
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c67dc35b964de9c40d7b6cd609b1230c
https://pubmed.ncbi.nlm.nih.gov/15618651
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