Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Makoto Monnai"'
Autor:
Daiko Wakita, Makoto Monnai, Kaname Yamamoto, Chinami Masuda, Masamichi Sugimoto, Keigo Yorozu, Mitsue Kurasawa, Osamu Kondoh, Ryo Nakamura, Chisako Ishimaru, Mari Kinoshita
Publikováno v:
Clinical & Experimental Metastasis
Brain metastases are common in patients with non-small-cell lung cancer (NSCLC). The efficacy of bevacizumab, an anti-vascular endothelial growth factor (VEGF) humanized antibody, has been demonstrated in patients with nonsquamous NSCLC. We establish
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65472fe8bff38367ac06cb54e27c0198
http://europepmc.org/articles/PMC7007905
http://europepmc.org/articles/PMC7007905
Autor:
Masami Suzuki, Shumpei Ishikawa, Etsuko Fujii, Chisako Ishimaru, Yoshie Kuroiwa, Daisuke Komura, Takashi Nishizawa, Kiyotaka Nakano, Hiroyuki Aburatani, Makoto Monnai
Publikováno v:
Oncology Reports
Ras homolog family member A (RHOA) mutations are driver genes in diffuse-type gastric cancers (DGCs), and we previously revealed that RHOA mutations contribute to cancer cell survival and cell migration through their dominant negative effect on Rho-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7fbfeabbd12f0bbde21304cde49e1d8
https://doi.org/10.3892/or.2019.7300
https://doi.org/10.3892/or.2019.7300
Autor:
Zen Itoh, Hiroyasu Muramatsu, Kenshi Kamei, Satoshi Ōmura, Hisanori Takanashi, Saori Matsuo, Kenji Yogo, Mitsu Onoma, Yoshiki Kawabe, Shuji Hayashi, Makoto Monnai, Masami Suzuki, Toshihiko Shiga, Ken-ichi Ozaki
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 35:788-796
SUMMARY 1 The aim of the present study was to evaluate the effects of mitemcinal (GM-611), an orally active motilin receptor agonist, on delayed gastric emptying in a canine model of diabetic gastroparesis and to compare these effects with those of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8146dd98527bfd2a59327add60966222
https://doi.org/10.1111/j.1440-1681.2008.04924.x
https://doi.org/10.1111/j.1440-1681.2008.04924.x
Autor:
Tamao Ono, Makoto Murakami, Junji Kuroda, Shin-ichi Muto, Kiyoshi Matsumoto, Makoto Monnai, Yuji Okuhara
Publikováno v:
Immunology. 116:373-380
Summary The Matsumoto Eosinophilic Shinshu (MES) rat is an inbred mutant strain that spontaneously develops systemic hypereosinophilia with eosinophilic inflammatory lesions similar to those associated with hypereosinophilic syndrome in humans and ot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71cc139c4ec7f810ac154b464013093a
https://doi.org/10.1111/j.1365-2567.2005.02237.x
https://doi.org/10.1111/j.1365-2567.2005.02237.x
Autor:
Yoshitaka Miyakawa, Masashi Tomisawa, Yasuyuki Ohnishi, Yasuo Ikeda, Yoshito Ueyama, Kanoko Kohmura, Makoto Monnai, Masahiro Kizaki, Mamoru Ito, Masato Nakamura
Publikováno v:
Biochemical and Biophysical Research Communications. 313:258-262
We developed a new experimental animal model of human multiple myeloma using immunodeficient NOD/SCID/gammac(null) (NOG) mice. A human myeloma cell line, U266, was intravenously inoculated into 20 NOG mice, all of which developed hind leg paralysis a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caa792e8b0cc2712c459cf8593752f0e
https://doi.org/10.1016/j.bbrc.2003.11.120
https://doi.org/10.1016/j.bbrc.2003.11.120
Autor:
Masato Nakamura, Kenji Kawai, Makoto Monnai, Tomoko Mizushima, Ikumi Katano, Hiroshi Suemizu, Mitsuru Murata, Takehiro Yamamoto, Nobuhito Goda, Chiyoko Nishime, Makoto Suematsu, Masatoshi Wakui
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 195(4)
Immunodeficient hosts exhibit high acceptance of xenogeneic or neoplastic cells mainly due to lack of adaptive immunity, although it still remains to be elucidated how innate response affects the engraftment. IL-2R common γ-chain (IL-2Rγc) signalin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c291e2dd31fddb1959541fdd9a14ef00
https://pubmed.ncbi.nlm.nih.gov/26170385
https://pubmed.ncbi.nlm.nih.gov/26170385
Publikováno v:
Nihon Chikusan Gakkaiho. 71:197-207
Bovine κ-casein produced cytotoxic activity toward mouse spleen cells when it was digested with bovine trypsin or chymotrypsin. The cytotoxic activity reached a maximum when the casein was digested with the trypsin at 45°C for 5h and was observed w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26a5c2287694bada68f38de40ca98be8
https://doi.org/10.2508/chikusan.71.197
https://doi.org/10.2508/chikusan.71.197
Autor:
Masami Hasegawa, Mamoru Ito, Masato Nakamura, Gary Peltz, Hiroshi Suemizu, Kenji Taniguchi, Makoto Monnai, Kenji Kawai, Tetsuya Mitsui, Masatoshi Wakui, Makoto Suematsu
To overcome the limitations of existing models, we developed a novel experimental in vivo platform for replacing mouse liver with functioning human liver tissue. To do this, a herpes simplex virus type 1 thymidine kinase (HSVtk) transgene was express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f273851b92174e73c8b9daee4bbf654c
https://europepmc.org/articles/PMC3648850/
https://europepmc.org/articles/PMC3648850/
Autor:
Hajime Otani, Makoto Monnai
Publikováno v:
Food and Agricultural Immunology. 5:219-229
The inhibitory effects of bovine milk κ‐casein and its enzymatic digests on the proliferative responses of mouse spleen lymphocytes induced or not induced by mitogens were studied with a colorimetric assay using 3‐(4,5‐dimethylthiazol‐2‐yl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57735178b287429045d17e98ac1dd57a
https://doi.org/10.1080/09540109309354801
https://doi.org/10.1080/09540109309354801
Autor:
Makoto Suematsu, Tomoko Mizushima, Mitsuyo Ohmura, Kenji Kawai, Takako Hishiki, Kyoji Ogoshi, Masahiro Matsuyama, Hiroshi Suemizu, Hiroyasu Makuuchi, Mitsuru Murata, Masatoshi Wakui, Daisuke Furukawa, Makoto Monnai, Tsuyoshi Chijiwa, Chiyoko Nishime, Masato Nakamura
Liver metastases of colorectal cancers significantly affect the prognoses of patients. To further understand the biological aspects of the metastatic phenotypes, we established the highly liver-metastatic human colorectal cancer cell subline SW48LM2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1d446b9d927a4fe2f0ae198aed4f049
https://europepmc.org/articles/PMC3436221/
https://europepmc.org/articles/PMC3436221/