Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Makoto Kawaguchi"'
Autor:
Yoshihiro Miyashita, MD, Yosuke Hirotsu, PhD, Yuki Nagakubo, MS, Hiroaki Kobayashi, MD, Makoto Kawaguchi, MD, Koki Hata, MD, Ryota Saito, MD, Yumiko Kakizaki, MD, Toshiharu Tsutsui, PhD, Toshio Oyama, MD, Masao Omata, MD
Publikováno v:
JTO Clinical and Research Reports, Vol 5, Iss 6, Pp 100679- (2024)
Introduction: NSCLC is a leading cause of cancer-related mortality worldwide. Specific genetic alterations, such as MET exon 14 (METex14) skipping, have been identified in NSCLC, allowing targeted therapy. Tepotinib, a highly selective MET inhibitor,
Externí odkaz:
https://doaj.org/article/02b007faf1354427b6783f95d8c35a84
Autor:
Toshiharu Tsutsui, Koki Hata, Makoto Kawaguchi, Hiroaki Kobayashi, Yumiko Kakizaki, Yoshihiro Miyashita
Publikováno v:
Thoracic Cancer, Vol 14, Iss 23, Pp 2310-2313 (2023)
Abstract Cytokine release syndrome (CRS) is a severe and life‐threatening toxicity typically reported in chimeric antigen receptor T cell therapy and is rarely reported in immune checkpoint inhibitor (ICI) therapy. This study reports the case of a
Externí odkaz:
https://doaj.org/article/11ecdeb4035c47c5a54ff48734bc68bb
Autor:
Yosuke Hirotsu, Yumiko Kakizaki, Akitoshi Saito, Toshiharu Tsutsui, Syunya Hanawa, Haruna Yamaki, Syuichiro Ide, Makoto Kawaguchi, Hiroaki Kobayashi, Yoshihiro Miyashita, Masao Omata
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-10 (2023)
Hirotsu, Kakizaki et al. assess the presence of pneumonia and pathogenesis during infection with different SARS-CoV-2 variants. The prevalence of pneumonia differs depending on the infectious variant, with the lowest prevalence and mild lung pathogen
Externí odkaz:
https://doaj.org/article/8084e50cd55a4111ae8f7d5a4de3d95b
Autor:
Eriko Nakamura, Kenji Hata, Yoshifumi Takahata, Hiroshi Kurosaka, Makoto Abe, Takaya Abe, Miho Kihara, Toshihisa Komori, Sachi Kobayashi, Tomohiko Murakami, Toshihiro Inubushi, Takashi Yamashiro, Shiori Yamamoto, Haruhiko Akiyama, Makoto Kawaguchi, Nobuo Sakata, Riko Nishimura
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Nakamura et al. used expression studies to identify an enrichment of Zfhx4 in cartilage and revealed through global gene knock-down that it is required for proper endochondral ossification in mice. They further demonstrated a physical and genetic int
Externí odkaz:
https://doaj.org/article/c38c2a6d2d8844b3af9e0bfa858e2f81
Autor:
Shun Shibata, Akiko Kuwahara, Masayo Sakaki-Yumoto, Makoto Kawaguchi, Tsuyoshi Ishii, Yoichi Honma
Publikováno v:
Heliyon, Vol 8, Iss 1, Pp e08729- (2022)
Allergic contact dermatitis (ACD) and atopic dermatitis (AD) are inflammatory eczematous skin diseases caused by various factors. Here, we report that topical application of the dipeptide, L-glutamic acid-L-tryptophan (L-Glu-L-Trp), improved symptoms
Externí odkaz:
https://doaj.org/article/3c582183a4a34eb6beb0f0e23372b1f5
Autor:
Hideharu Mikami, Makoto Kawaguchi, Chun-Jung Huang, Hiroki Matsumura, Takeaki Sugimura, Kangrui Huang, Cheng Lei, Shunnosuke Ueno, Taichi Miura, Takuro Ito, Kazumichi Nagasawa, Takanori Maeno, Hiroshi Watarai, Mai Yamagishi, Sotaro Uemura, Shinsuke Ohnuki, Yoshikazu Ohya, Hiromi Kurokawa, Satoshi Matsusaka, Chia-Wei Sun, Yasuyuki Ozeki, Keisuke Goda
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
High throughput imaging flow cytometry suffers from trade-offs between throughput, sensitivity and spatial resolution. Here the authors introduce a method to virtually freeze cells in the image acquisition window to enable 1000 times longer signal in
Externí odkaz:
https://doaj.org/article/970eb547b4534e9b8248827dc2f21c9b
Autor:
Makoto Kawaguchi, Masayuki Nakayama, Masashi Bando, Shu Hisata, Naoko Mato, Takuji Suzuki, Tamiko Takemura, Koichi Hagiwara
Publikováno v:
Respiratory Medicine Case Reports, Vol 31, Iss , Pp 101279- (2020)
A 65-year-old woman had a ground glass nodule, which was suspicious for lung cancer, in her right lung S6 by chest computed tomography. For diagnosis, video-assisted thoracoscopic surgery was performed, and the specimen showed a pathological pattern
Externí odkaz:
https://doaj.org/article/d6fdba6ca4f5444db00559d68ab53af3
Autor:
Masayuki Sakiyama, Hirotaka Matsuo, Hirofumi Nakaoka, Yusuke Kawamura, Makoto Kawaguchi, Toshihide Higashino, Akiyoshi Nakayama, Airi Akashi, Jun Ueyama, Takaaki Kondo, Kenji Wakai, Yutaka Sakurai, Ken Yamamoto, Hiroshi Ooyama, Nariyoshi Shinomiya
Publikováno v:
BMC Medical Genetics, Vol 19, Iss 1, Pp 1-6 (2018)
Abstract Background Gout is a common disease resulting from hyperuricemia which causes acute arthritis. A recent genome-wide association study (GWAS) of gout identified three new loci for gout in Han Chinese: regulatory factor X3 (RFX3), potassium vo
Externí odkaz:
https://doaj.org/article/3fdd0a2def0c4ba9a6ed1afd843b8632
Autor:
Yusuke Kawamura, Akiyoshi Nakayama, Seiko Shimizu, Yu Toyoda, Yuichiro Nishida, Asahi Hishida, Sakurako Katsuura-Kamano, Kenichi Shibuya, Takashi Tamura, Makoto Kawaguchi, Satoko Suzuki, Satoko Iwasawa, Hiroshi Nakashima, Rie Ibusuki, Hirokazu Uemura, Megumi Hara, Kenji Takeuchi, Tappei Takada, Masashi Tsunoda, Kokichi Arisawa, Toshiro Takezaki, Keitaro Tanaka, Kimiyoshi Ichida, Kenji Wakai, Nariyoshi Shinomiya, Hirotaka Matsuo
Publikováno v:
Biomedicines, Vol 9, Iss 8, p 1012 (2021)
Background: Renal hypouricemia (RHUC) is characterized by a low serum uric acid (SUA) level and high fractional excretion of uric acid (FEUA). Further studies on FEUA in hypouricemic individuals are needed for a more accurate diagnosis of RHUC. Metho
Externí odkaz:
https://doaj.org/article/374df1a21f18430bb1805654d36a9794
Autor:
Masayuki Sakiyama, Hirotaka Matsuo, Airi Akashi, Seiko Shimizu, Toshihide Higashino, Makoto Kawaguchi, Akiyoshi Nakayama, Mariko Naito, Sayo Kawai, Hiroshi Nakashima, Yutaka Sakurai, Kimiyoshi Ichida, Toru Shimizu, Hiroshi Ooyama, Nariyoshi Shinomiya
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-6 (2017)
Abstract Gout is caused by hyperuricemia, with alcohol consumption being an established risk factor. Alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) are crucial enzymes for alcohol metabolism. We recently performed a genome-wide associa
Externí odkaz:
https://doaj.org/article/fc32a65889214026935183695432fcf6