Výsledky vyhledávání - "Makoto Kamezawa"

Black carrot extract protects against hepatic injury through epigenetic modifications

Autor: Atsuko Kitano, Toshio Norikura, Isao Matsui‐Yuasa, Hiromi Shimakawa, Makoto Kamezawa, Akiko Kojima‐Yuasa

Publikováno v: Journal of Food Biochemistry. 46

We studied the epigenetic regulation of how black carrot extract (BCE) protects against ethanol-induced hepatic damage. We have shown that the butanol-extracted fraction of BCE (BCE-BuOH) increased intracellular cyclic adenosine monophosphate (cAMP)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67659ee174ca0e4037e318c8633b04cf
https://doi.org/10.1111/jfbc.14292

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Chemoenzymatic Synthesis of (R)-(+)-Patulolide A, a Macrolide Antibiotic Isolated from Penicillium urticae

Autor: Masaya Kitamura, Makoto Kamezawa, Takehiko Ohtani, Hiroyuki Nagaoka, Yoshinobu Naoshima, Hojun Tachibana

Publikováno v: Liebigs Annalen. 1996:167-170

(R)-(+)-Patulolide A [(R)-1] was synthesized with an enantiomeric purity of almost 100% e.e. by a two-step lipase-catalyzed enantioselective hydrolysis of racemic thioketal acetate (±)-11.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::96356c9b67694be0e397378bda2cb0cf
https://doi.org/10.1002/jlac.199619960204

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An efficient novel synthesis of β-(azuleno[1,2-b]benzothienyl)- and β-(azuleno[2,1-b]benzothienyl)-α,β-unsaturated ketones by the tropylium ion-mediated intramolecular furan ring-opening reaction and X-ray investigation of methyl ketone derivative1

Autor: Masao Hashimoto, Makoto Kamezawa, Kimiaki Yamamura, Takatomo Kimura, Takehiko Otani, Yuuko Houda

Publikováno v: Org. Biomol. Chem.. 2:1413-1418

Intramolecular reaction of 2-tropylio-3-(5-substituted 2-furyl)benzothiophenes (3), prepared from the corresponding 2-cycloheptatrienyl-3-(5-substituted 2-furyl)benzothiophenes (2), afforded the β-(azuleno[1,2-b]benzothienyl)-α,β-unsaturated keton

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6011b89c575d92a1882fe0fa8859c304
https://doi.org/10.1039/b401579g

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Chemoenzymatic synthesis of (+)-docosa-4,15-dien-1-yn-3-ol, a component of the marine sponge Cribrochalina vasculum, and confirmation of the structure and absolute configuration of the acetylenic alcohol, by lipase-catalysed biotransformations

Autor: Kiyoshi Morishita, Yoshinobu Naoshima, Makoto Kamezawa, Midori Kishimoto, Mayumi Kawase, Takehiko Ohtani, Hojun Tachibana

Publikováno v: Journal of the Chemical Society, Perkin Transactions 1. :513-518

The (4E,15Z)- and (4E,15E)-isomers of (+)-docosa-4,15-dien-1-yn-3-ol 1, isolated from the marine sponge Cribrochalina vasculum, were synthesized in highly enantiomerically pure form by lipase-mediated biotransformation with Novozym 435, and the struc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b5030b820427c8735a1dccc4e05772da
https://doi.org/10.1039/a807681b

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Enantioselectivity of Candida antarctica lipase for some synthetic substrates including aliphatic secondary alcohols

Autor: Takehiko Ohtani, Hojun Tachibana, Hiroki Nakatsukasa, Yoshinobu Naoshima, Makoto Kamezawa

Publikováno v: Journal of Molecular Catalysis B: Enzymatic. 4:53-60

Candida antarctica lipase (Novozym 435) showed good to high enantioselectivity in the acylation of aliphatic and aromatic secondary alcohols ( E = 38−166), and higher enantioselectivity in the hydrolysis of their corresponding acetates than other l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::16c563cd68a11b135aaf11ed04bc6632
https://doi.org/10.1016/s1381-1177(97)00021-0

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Biocatalytic synthesis of (S)-2-tridecanyl acetate and (S)-2-pentadecanyl acetate, aggregation pheromone components ofDrosophila mulleri andD. busckii, by enantioselective hydrolysis with lipase

Autor: Makoto Kamezawa, Hojun Tachibana, Takehiko Ohtani, Yoshinobu Naoshima

Publikováno v: Journal of Chemical Ecology. 20:1057-1061

The two chiral pheromone acetates, (S)-2-tridecanyl acetate and (S)-2-pentadecanyl acetate, were synthesized with an enantiomeric excess (e.e.) of almost 100% byPseudomonas cepacia lipase-catalyzed hydrolysis of their corresponding racemic acetates i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68da6b09e1b55afc60963358bad6b2e3
https://doi.org/10.1007/bf02059742

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