Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Makoto Kakitani"'
Autor:
Shin-ichiro Takayanagi, Sayaka Chuganji, Masahiro Tanaka, Bo Wang, Saki Hasegawa, Ken Fukumoto, Nariaki Wasano, Makoto Kakitani, Nakaba Ochiai, Yohei Kawai, Tatsuki Ueda, Akihiro Ishikawa, Yuko Kurimoto, Asami Fukui, Sanae Kamibayashi, Eri Imai, Atsushi Kunisato, Hajime Nozawa, Shin Kaneko
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Memory T cells demonstrate superior in vivo persistence and antitumor efficacy. However, methods for manufacturing less differentiated T cells are not yet well-established. Here, we show that producing chimeric antigen receptor (CAR)-T cells
Externí odkaz:
https://doaj.org/article/43fa49bb478a41ba978179bcffcbdba4
Autor:
Dong-Hee Kang, Fiona Louis, Hao Liu, Hiroshi Shimoda, Yasutaka Nishiyama, Hajime Nozawa, Makoto Kakitani, Daisuke Takagi, Daijiro Kasa, Eiji Nagamori, Shinji Irie, Shiro Kitano, Michiya Matsusaki
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Mammalian cell-based cultured meat has mostly been unstructured, leaving a demand for artificial steak-like meat. Here the authors present an assembled steak-like tissue of bovine skeletal muscle, adipose tissue, and blood capillary tissue fabricated
Externí odkaz:
https://doaj.org/article/b5e29c0b88854bbbbad989dd8f2ac9df
Autor:
Makoto Kakitani, Takagi Daisuke, Daijiro Kasa, Michiya Matsusaki, Hiroshi Shimoda, Yasutaka Nishiyama, Hao Liu, Dong-Hee Kang, Shiro Kitano, Hajime Nozawa, Fiona Louis, Shinji Irie, Eiji Nagamori
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications
Nature Communications
With the current interest in cultured meat, mammalian cell-based meat has mostly been unstructured. There is thus still a high demand for artificial steak-like meat. We demonstrate in vitro construction of engineered steak-like tissue assembled of th
Autor:
Kengo Yamawaki, Shinobu Ueda, Tsutomu Okada, Takeshi Oshima, Makoto Kakitani, Takashi Kato, Kazuma Tomizuka
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e78076 (2013)
Bone morphogenetic proteins (BMPs)/growth differentiation factors (GDFs), which belong to the TGF-beta superfamily, are pleiotropic factors that play a role in regulating the embryonic development and postnatal homeostasis of various organs and tissu
Externí odkaz:
https://doaj.org/article/b279ef89ebb6451799678c6a48928aa8
Engineered Whole Cut Meats Assembled of Cell Fibers Constructed by Tendon-Gel Integrated Bioprinting
Autor:
Daijiro Kasa, Michiya Matsusaki, Hajime Nozawa, Takagi Daisuke, Hiroshi Shimoda, Fiona Louis, Hao Liu, Dong-Hee Kang, Shinji Irie, Yasutaka Nishiyama, Makoto Kakitani, Shiro Kitano, Eiji Nagamori
With the current interest in artificial meat, mammalian cell-based cultured meat has mostly been in minced form. There is thus still a high demand for artificial steak-like meat. Herein, we demonstrate in vitro construction of engineered steak-like m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c323d6118494b93ea97f7543f7153ab
https://doi.org/10.21203/rs.3.rs-91978/v1
https://doi.org/10.21203/rs.3.rs-91978/v1
Autor:
Kenji Oritani, Takao Sudo, Daisuke Okuzaki, Yuzuru Kanakura, Eiichi Morii, Akihiko Shimono, Kentaro Fukushima, Kengo Yamawaki, Paul W. Kincade, Makoto Kakitani, Kazuma Tomizuka, Takafumi Yokota, Michiko Ichii, Yukiko Doi, Tomohiko Ishibashi, Yoko Habuchi
Publikováno v:
European Journal of Immunology. 45:1390-1401
Mammals have evolved to protect their offspring during early fetal development. Elaborated mechanisms induce tolerance in the maternal immune system for the fetus. Female hormones, mainly estrogen, play a role in suppressing maternal lymphopoiesis. H
Autor:
Kazuma Tomizuka, Takeyoshi Yamashita, Motoo Takahashi, Yuri Shibasaki, Kazunori Hanaoka, Nobuaki Etoh, Makoto Kakitani, Michiko Hayasaka
Publikováno v:
Biochemical and Biophysical Research Communications. 381:482-486
NaPi-IIb encodes a Na(+)-dependent Pi co-transporter, which is expressed in various adult tissues and mediates transport of extracellular Pi ions coupling with Na(+) ion. To define the role of NaPi-IIbin vivo, NaPi-IIb gene deficient mice were genera
Autor:
Makoto Kakitani, Tsutomu Okada, Kazuma Tomizuka, Kengo Yamawaki, Takeshi Oshima, Yuichiro Kondo
Publikováno v:
Scientific Reports
Bone morphogenetic proteins (BMPs) are multi-functional growth factors that belong to the TGF-beta superfamily. Recently, several soluble BMP receptors, such as ActRIIA-Fc, ActRIIB-Fc and ALK1-Fc, are undergoing clinical trials. Both BMPRIA and BMPRI
Autor:
Natsuko Fujita, Michiko Ichii, Kengo Yamawaki, Yuzuru Kanakura, Tetsuo Maeda, Makoto Kakitani, Kazuma Tomizuka, Kenji Oritani, Norimitsu Saitoh, Takafumi Yokota
Publikováno v:
Experimental hematology. 43(11)
Recent studies have revealed the crucial role of the niche which supports B-lymphocyte differentiation from hematopoietic stem cells. In this study, we aimed to identify a novel regulator of B lymphopoiesis secreted in the specific niche using the si
Autor:
Kazuma Tomizuka, Makoto Kakitani, Kaori Ono, Takeshi Oshima, Takeyoshi Yamashita, Seiji Fukumoto, Takashi Shimada, Yamazaki Yuji, Toshiro Fujita, Itaru Urakawa, Motoo Takahashi, Hisashi Hasegawa
Publikováno v:
American Journal of Physiology-Renal Physiology. 289:F1088-F1095
FGF23 suppresses both serum phosphate and 1,25-dihydroxyvitamin D [1,25D] levels in vivo. Because 1,25D itself is a potent regulator of phosphate metabolism, it has remained unclear whether FGF23-induced changes in phosphate metabolism were caused by