Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Makoto Hamanoue"'
Publikováno v:
Stem Cell Research, Vol 14, Iss 1, Pp 68-78 (2015)
Neural stem/progenitor cells (NPCs) express a variety of asparagine-linked oligosaccharide chains, called N-glycans, on the cell surface, and mainly produce hybrid-type and complex-type N-glycans. However, the expression profiles and roles of N-acety
Externí odkaz:
https://doaj.org/article/9c4e5d4cda1f4f0b9280a10a81a777a4
Publikováno v:
Neuroscience Letters. 699:115-121
p38 mitogen-activated protein (MAP) kinase (p38) is a member of the MAP kinase family. Previous reports using p38 chemical inhibitors have suggested that its activation contributes to hippocampal neuronal cell death rather than cell survival. In this
Autor:
Chie Fujisawa, Makoto Hamanoue, Yayoi Kawano, Daiki Murata, Yuri Akishima-Fukasawa, Tetsuya Okaneya, Takeo Minematsu, Hiromi Sanada, Kayo Tsuburaya, Takuma Isshiki, Tetsuo Mikami, Takehisa Hanawa, Yoshikiyo Akasaka
Publikováno v:
Journal of Investigative Dermatology. 142:1990-2002.e4
As a candidate microRNA antifibrotic effector in skin wounds, miR-146b-5p was upregulated by basic FGF, and PDGFRα was identified as a direct target of miR-146b-5p in fibroblasts. The treatment of fibroblasts with a miR-146b-5p mimic markedly downre
Autor:
Seisuke Hattori, Yasuhiro Terasaki, Ikuroh Ohsawa, Masumi Iketani, Suzuki Tetsuya, Yusuke Kajimoto, Kozue Tonaki, Naomi Kuwahara, Mika Terasaki, Akira Shimizu, Makoto Hamanoue, Mayumi Takahashi, Hideo Kawaguchi, Jumi Ohsiro
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 99(6)
Although inhibition of epidermal growth factor receptor (EGFR)-mediated cell signaling by the EGFR tyrosine kinase inhibitor gefitinib is highly effective against advanced non-small cell lung cancer, this drug might promote severe acute interstitial
Publikováno v:
Pediatrics international : official journal of the Japan Pediatric Society. 61(4)
Background Menkes disease (MNK; MIN 309400) is an X-linked recessive lethal disorder of copper metabolism caused by mutations in ATP7A (MIM 300011), which encodes a transmembrane copper-transporting P-type ATPase. This study assessed mutations in ATP
Publikováno v:
Neurochemical research. 43(2)
The responses of inhibitory neurons/synapses to motoneuron injury in the cranial nervous system remain to be elucidated. In this study, we analyzed GABAA receptor (GABAAR) and GABAergic neurons at the protein level in the transected rat facial nucleu
Publikováno v:
Biochemical and Biophysical Research Communications. 429:142-147
Hippocalcin (Hpca) is a Ca 2+ -binding protein that is expressed in neurons and contributes to neuronal plasticity. We purified a 48 kDa Hpca-associated protein from rat brain and identified it to be the creatine kinase B (CKB) subunit, which constit
Autor:
Makoto Hamanoue, Ikuroh Ohsawa, Yoshikiyo Akasaka, Kayo Tsuburaya, Toru Ogata, Tetsuo Mikami, Keiko Ohsawa, Kazuhito Morioka, Masaaki Kobayashi, Ken Takamatsu
Publikováno v:
Scientific reports, vol 6, iss 1
Scientific Reports
Scientific Reports
Endogenous neural stem/progenitor cells (NPCs) can migrate toward sites of injury, but the migration activity of NPCs is insufficient to regenerate damaged brain tissue. In this study, we showed that p38 MAP kinase (p38) is expressed in doublecortin-
Autor:
Makoto Hamanoue, Hideyuki Okano
Publikováno v:
Journal of Cellular Physiology. 226:1433-1438
The isolation of neural stem cells (NSCs) has been hampered by the lack of valid cell-surface antigens on NSCs, and novel valuable markers have been proposed. Glycan (oligosaccharide chain) is a potential candidate as a marker to isolate NSCs, becaus
Publikováno v:
Journal of Neuroscience Research. 86:2179-2189
The p38 mitogen-activated protein kinase (MAPK) is induced in response to environmental stress. Although p38 MAPK has been implicated in diverse cellular processes, including cell proliferation, differentiation, and survival of differentiated cells i